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The protein encoded by IMPG2 binds chondroitin sulfate and hyaluronan and is a proteoglycan. Additionally we are shipping Interphotoreceptor Matrix Proteoglycan 2 Antibodies (6) and Interphotoreceptor Matrix Proteoglycan 2 Kits (4) and many more products for this protein.
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IMPG1 (show IMPG1 Proteins) and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families.
Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life.
identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa
IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival
The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.
interphotoreceptor matrix proteoglycan 2
, sialoprotein associated with cones and rods proteoglycan
, IPM 200
, interphotoreceptor matrix proteoglycan IPM 200
, interphotoreceptor matrix proteoglycan of 200 kDa