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Inverted Formin, FH2 and WH2 Domain Containing Proteins (INF2)

INF2 represents a member of the formin family of proteins. Additionally we are shipping INF2 Antibodies (43) and INF2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
INF2 64423 Q27J81
INF2 70435 Q0GNC1
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Top INF2 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

INF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Inverted Formin, FH2 and WH2 Domain Containing (INF2) Interaction Partners

Human Inverted Formin, FH2 and WH2 Domain Containing (INF2) interaction partners

  1. The authors propose Spire1C isoform cooperates with INF2 to regulate actin assembly at endoplasmic reticulum-mitochondrial contacts.

  2. Report novel mutations in the inverted formin 2 gene of Chinese families contributing to focal segmental glomerulosclerosis.

  3. Assembly and turnover of short actin filaments by the formin (show FMN1 Proteins) INF2 and profilin (show PFN1 Proteins).

  4. INF2 mutations are associated with focal segmental glomerulosclerosis.

  5. this study identifed three novel mutations of INF (show GIF Proteins) likely efect hereditary neuropathy with glomerulopathy.

  6. actin monomer binding to the DAD of INF2 competes with the DID/DAD interaction, thereby activating actin polymerization

  7. INF2 mutation was detected both father and his son

  8. This study showed that INF2 mutations in Charcot-Marie-Tooth disease complicated with focal segmental glomerulosclerosis.

  9. In podocytes, INF2 appears to be an important modulator of actin-dependent behaviors that are under the control of Rho/mDia signaling.

  10. INF2 mutations were found in 2 of 281 individuals with sporadicfocal and segmental glomerulosclerosis

Mouse (Murine) Inverted Formin, FH2 and WH2 Domain Containing (INF2) interaction partners

  1. The perinuclear actin rim structure colocalized with INF2 on stimulation, and INF2 depletion resulted in attenuation of the rim formation.

  2. INF2 plays a role in controlling morphological, but not compositional maturation of focal adhesions

  3. Splice variant-specific cellular function of the formin (show FMN1 Proteins) INF2 in maintenance of Golgi architecture.

  4. Data suggest a role for INF1 in microtubule modification and potentially in coordinating microtubule and F-actin structure.

INF2 Protein Profile

Protein Summary

This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

Gene names and symbols associated with INF2

  • inverted formin, FH2 and WH2 domain containing (INF2)
  • inverted formin, FH2 and WH2 domain containing (Inf2)
  • 2610204M08Rik protein
  • AA589465 protein
  • AW125550 protein
  • C14orf151 protein
  • C14orf173 protein
  • CMTDIE protein
  • EG629699 protein
  • FSGS5 protein
  • pp9484 protein

Protein level used designations for INF2

HBEAG-binding protein 2 binding protein C , HBEBP2-binding protein C , inverted formin-2 , formin, inverted

GENE ID SPECIES
64423 Homo sapiens
70435 Mus musculus
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