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Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. Additionally we are shipping Involucrin Antibodies (191) and Involucrin Kits (31) and many more products for this protein.
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Together, these results suggest that GR modulates involucrin expression of keratinocytes by regulating the intracellular signaling network in a ligand-independent manner.
over-expression of Nnat (show NNAT Proteins) was evident along with involucrin and cytokeratin1 expression
involucrin is up-regulated in psoriatic keratinocytes
KLF4 (show KLF4 Proteins) is part of a multiprotein complex that interacts that the hINV promoter distal regulatory region to drive differentiation-dependent hINV gene expression in epidermis.
Compared with the control, the level of expression of the IVL gene in NCTC 2544 cells was increased after 8 h of treatment with hyaluronic acid or Plantaricin A preparations.
Therefore, together with trichohyalin, the cross-linking due to involucrin is also responsible for the mechanical resistance of the corneous trabeculae present among the empty spaces of the medulla of the human hair.
The authors found that HPV 16 E6 but not E7 repressed IVL promoter activity in proliferating human foreskin keratinocyte cells.
expression of the epidermal differentiation complex genes filaggrin (show FLG Proteins) and involucrin was strongly decreased directly by IL-13 (show IL13 Proteins).
Transcriptional activation of the involucrin gene by calcium in keratinocytes.
involucrin gene contains distinct regulatory elements that regulate expression during epidermal differentiation
The Inv (show INVS Proteins)-Cldn6 (show CLDN6 Proteins)-CDelta206 transgenic mice displayed a developmental delay in epidermal permeability barrier formation, as shown by the expression of keratins and Cldns, and by X-Gal (show GAL Proteins) penetration assays.
the normally robust injury response mechanism of the epidermis is lost in the aging Involucrin-Cldn6 (show CLDN6 Proteins)-CDelta196 transgenic epidermis
analysis of evolutionary relations of the mouse based on repeats at a precise location in the coding region of the involucrin gene
Skin biopsies from STAT6 (show STAT6 Proteins) transgenic mice were deficient in the expression and production of loricrin (show LOR Proteins) and involucrin.
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.