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Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) Proteins (ISCA2)

The protein encoded by ISCA2 is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. Additionally we are shipping Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ISCA2 122961 Q86U28
Rat ISCA2 ISCA2 500694  
ISCA2 74316 Q9DCB8
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Top Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,317.33
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ISCA2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) (ISCA2) Interaction Partners

Human Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) (ISCA2) interaction partners

  1. We identified a homoallelic missense founder mutation in ISCA2 leading to mitochondrial depletion and reduced complex I activity as well as decreased ISCA2, ISCA1 (show ISCA1 Proteins) and IBA57 (show IBA57 Proteins) expression in fibroblasts.

  2. The structural plasticity of the dimeric state of the [2Fe-2S] bound form of human GRX5 (show GLRX5 Proteins) is the crucial factor that allows an efficient cluster transfer to the partner proteins human ISCA1 (show ISCA1 Proteins) and ISCA2 by a specific protein-protein recognition mechanism.

  3. ISCA1 (show ISCA1 Proteins), ISCA2, and IBA57 (show IBA57 Proteins) were depleted by RNA interference. Depleted cells contained massively swollen and enlarged mitochondria that were virtually devoid of cristae membranes, demonstrating the importance of these proteins for mitochondrial biogenesis.

Mouse (Murine) Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) (ISCA2) interaction partners

  1. Data suggest that miR (show MLXIP Proteins)-210 induced repression of ISCU1/2 may contribute to HIF-1alpha (show HIF1A Proteins)-triggered alterations in neuronal energy metabolism after nickel exposure.

Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) (ISCA2) Protein Profile

Protein Summary

The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ISCA2

  • iron-sulfur cluster assembly 2 (ISCA2)
  • iron-sulfur cluster assembly 2 (Isca2)
  • iron-sulfur cluster assembly 2 homolog (S. cerevisiae) (ISCA2)
  • iron-sulfur cluster assembly 2 homolog (S. cerevisiae) (Isca2)
  • 0710001C05Rik protein
  • 5730594E03Rik protein
  • c14_5557 protein
  • Hbld1 protein
  • ISA2 protein
  • RGD1563216 protein

Protein level used designations for ISCA2

HESB-like domain-containing protein 1 , iron-sulfur cluster assembly 2 homolog, mitochondrial , HESB like domain containing 1 , iron-sulfur cluster assembly 2 homolog

GENE ID SPECIES
122961 Homo sapiens
500694 Rattus norvegicus
490783 Canis lupus familiaris
613290 Bos taurus
74316 Mus musculus
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