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Isocitrate Dehydrogenase 3 (NAD+) alpha Proteins (IDH3A)

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Additionally we are shipping Isocitrate Dehydrogenase 3 (NAD+) alpha Antibodies (41) and Isocitrate Dehydrogenase 3 (NAD+) alpha Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IDH3A 3419 P50213
IDH3A 67834 Q9D6R2
IDH3A 114096 Q99NA5
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Top Isocitrate Dehydrogenase 3 (NAD+) alpha Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,143.17
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IDH3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) Interaction Partners

Human Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) interaction partners

  1. The silencing of IDH3a significantly delayed tumor growth by suppressing the HIF-1 (show HIF1A Proteins)-mediated Warburg effect and angiogenesis.

  2. for IDH (show IDH1 Proteins), a normal alpha subunit (show POLG Proteins) is required for catalytic activity and alpha-Arg88 likely participates in the isocitrate site, whereas the beta and gamma subunits have roles in the nucleotide functions of this allosteric enzyme

  3. active sites of the human NAD-IDH are shared between alpha and gamma subunits and between alpha and beta subunits

  4. Asp181 is essential for nicotinamide-adenine dinucleotide (NAD)-specific IDH (show IDH1 Proteins) alpha subunit (show POLG Proteins) catalysis and may also facilitate the binding of substrates.

Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) Protein Profile

Protein Summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Gene names and symbols associated with IDH3A

  • isocitrate dehydrogenase 3 (NAD+) alpha (idh3a)
  • isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A)
  • isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a)
  • 1110003P10Rik protein
  • 1500012E04Rik protein
  • AA407078 protein
  • AI316514 protein
  • BG1 protein
  • IDH3A protein
  • MGC76128 protein
  • zgc:56380 protein
  • zgc:85631 protein

Protein level used designations for IDH3A

isocitrate dehydrogenase 3 (NAD+) alpha , isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial , mitochondrial isocitrate dehydrogenase (nad) subunit alpha , H-IDH alpha , NAD(+)-specific ICDH subunit alpha , NAD(H)-specific isocitrate dehydrogenase alpha subunit , NAD+-specific ICDH , isocitrate dehydrogenase (NAD+) alpha chain , isocitric dehydrogenase subunit alpha , isocitrate dehydrogenase subunits 3/4

GENE ID SPECIES
394979 Xenopus (Silurana) tropicalis
453565 Pan troglodytes
677715 Macaca mulatta
100528472 Ictalurus punctatus
393926 Danio rerio
444419 Xenopus laevis
415362 Gallus gallus
3419 Homo sapiens
479066 Canis lupus familiaris
282446 Bos taurus
67834 Mus musculus
114096 Rattus norvegicus
100157242 Sus scrofa
100172089 Pongo abelii
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