You are viewing an incomplete version of our website. Please click to reload the website as full version.

Jumonji, AT Rich Interactive Domain 2 Proteins (JARID2)

JARID2 encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. Additionally we are shipping JARID2 Antibodies (56) and JARID2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
JARID2 16468 Q62315
JARID2 3720 Q92833
Rat JARID2 JARID2 681740  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top JARID2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

JARID2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Jumonji, AT Rich Interactive Domain 2 (JARID2) Interaction Partners

Mouse (Murine) Jumonji, AT Rich Interactive Domain 2 (JARID2) interaction partners

  1. ESCs (show NR2E3 Proteins) lacking Jarid2 show constitutive Nanog (show NANOG Proteins) expression, reduced PCP (show BMP1 Proteins)/Wnt (show WNT2 Proteins) signaling and form more than one ICM upon injection to E3.5 mouse blastocysts.

  2. Jarid2 is a novel player in iNKT cell maturation that regulates PLZF (show ZBTB16 Proteins) expression by modulating H3K9 methylation

  3. Jarid2 is an important component of PRC2 that has a central role in coordinating hematopoietic stem and progenitor cell function

  4. miR (show MLXIP Proteins)-155 regulates the fate of Th17 and Treg cells and miR (show MLXIP Proteins)-155 contributes to Th17 cell function by suppressing the inhibitory effects of Jarid2.

  5. Data indicate that upon stimulation of muscle cells with IFN-gamma (show IFNG Proteins), JARID2 and other members of the Polycomb (show CBX2 Proteins) repressive complex 2 (PRC2) were recruited to promoters to repress myogenesis.

  6. Jarid2 exhibits nucleosome-binding activity that contributes to PRC2 stimulation

  7. Jarid2 (Jumonji, AT rich interactive domain 2) regulates NOTCH1 (show NOTCH1 Proteins) expression via histone modification in the developing heart.

  8. these studies identify JARID2, MTF2 (show MTF2 Proteins), and esPRC2p48 as important regulatory subunits of PRC2 in ES cells and reveal critical functions of these subunits

  9. Jarid2 is required for the scheduled proliferation of epidermal stem and progenitor cells necessary to maintain epidermal homeostasis.

  10. Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 (show NOTCH1 Proteins) expression

Human Jumonji, AT Rich Interactive Domain 2 (JARID2) interaction partners

  1. Data further strengthen the conclusion that JARID2 polymorphisms are associated with NSOC susceptibility.

  2. JARID2 inhibits leukemia cell proliferation by regulating CCND1 (show CCND1 Proteins) expression

  3. TGF-ss-dependent expression changes of EMT (show ITK Proteins)-related genes were inhibited by JARID2 knockdown and enhanced by JARID2 overexpression.

  4. Results suggest a regulation loop where Jarid2 protein methylation fine-tunes polycomb (show CBX2 Proteins) repressive complex 2 (PRC2) activity depending on the chromatin context.

  5. Jarid2 is an important component of PRC2 that has a central role in coordinating hematopoietic stem and progenitor cell function

  6. Decreased miRNA-940 affects the proliferation and migration of the progenitor cells of the secondary heart field by targeting JARID2.

  7. miR (show MLXIP Proteins)-155 regulates the fate of Th17 and Treg cells and miR (show MLXIP Proteins)-155 contributes to Th17 cell function by suppressing the inhibitory effects of Jarid2.

  8. The interaction of JARID2 at these promoters is dependent on EED (show EED Proteins).

  9. Jarid2 is an important mediator of Xist-induced PRC2 targeting.

  10. The presence of long noncoding RNAs stimulated JARID2-EZH2 (show EZH2 Proteins) interactions in vitro and JARID2-mediated recruitment of PRC2 to chromatin.

JARID2 Protein Profile

Protein Summary

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Gene names and symbols associated with JARID2

  • jumonji, AT rich interactive domain 2 (JARID2)
  • jumonji, AT rich interactive domain 2a (jarid2a)
  • jumonji, AT rich interactive domain 2 (jarid2)
  • jumonji, AT rich interactive domain 2 (LOC100230783)
  • jumonji, AT rich interactive domain 2 (Jarid2)
  • jarid2 protein
  • JMJ protein
  • jumonji protein

Protein level used designations for JARID2

jumonji, AT rich interactive domain 2 , jumonji, AT rich interactive domain 2 protein , protein Jumonji-like , jumonji/ARID domain-containing protein 2 , protein Jumonji , jumonji homolog , jumonji-like protein

GENE ID SPECIES
462450 Pan troglodytes
100007426 Danio rerio
100025851 Monodelphis domestica
100051819 Equus caballus
100217357 Xenopus (Silurana) tropicalis
100230783 Taeniopygia guttata
100435999 Pongo abelii
16468 Mus musculus
3720 Homo sapiens
478729 Canis lupus familiaris
100524569 Sus scrofa
528253 Bos taurus
681740 Rattus norvegicus
420839 Gallus gallus
Selected quality suppliers for JARID2 Proteins (JARID2)
Did you look for something else?