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anti-K(lysine) Acetyltransferase 5 (KAT5) Antibodies

The protein encoded by KAT5 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. Additionally we are shipping K(lysine) Acetyltransferase 5 Proteins (12) and K(lysine) Acetyltransferase 5 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KAT5 10524 Q92993
KAT5 81601 Q8CHK4
KAT5 192218 Q99MK2
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Top anti-K(lysine) Acetyltransferase 5 Antibodies at antibodies-online.com

Showing 10 out of 156 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-HTATIP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: THP-1 cell lysate WB Suggested Anti-HTATIP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HTATIP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: COLO205 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-HTATIP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-HTATIP Pab (ABIN387933) in Jurkat cell line lysates (35 µg/lane). HTATIP(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-HTATIP Pab(ABIN387933) in mouse liver tissue lysate (35 µg/lane). HTATIP(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-HTATIP Pab (ABIN387934) in CEM cell line tissue lysate (35 µg/lane).HTATIP(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using TIP60 (Phospho-Ser86) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using Tip60 (Phospho-Ser90) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TIP60 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

KAT5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-K(lysine) Acetyltransferase 5 Antibodies

  1. Human Polyclonal KAT5 Primary Antibody for EIA, WB - ABIN356624 : Legube, Linares, Tyteca, Caron, Scheffner, Chevillard-Briet, Trouche: Role of the histone acetyl transferase Tip60 in the p53 pathway. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN356624

  2. Human Polyclonal KAT5 Primary Antibody for EIA, WB - ABIN356625 : Patel, Du, Ard, Phillips, Carella, Chen, Rakowski, Chatterjee, Lieberman, Lane, Blobel, McMahon: The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. in Molecular and cellular biology 2004 (PubMed)
    Show all 3 references for ABIN356625

  3. Human Polyclonal KAT5 Primary Antibody for IHC, ELISA - ABIN1532173 : Kamine, Elangovan, Subramanian, Coleman, Chinnadurai: Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. in Virology 1996 (PubMed)
    Show all 2 references for ABIN1532173

  4. Human Polyclonal KAT5 Primary Antibody for IF, IHC - ABIN1532534 : Legube, Trouche: Identification of a larger form of the histone acetyl transferase Tip60. in Gene 2003 (PubMed)
    Show all 2 references for ABIN1532534

  5. Human Polyclonal KAT5 Primary Antibody for WB - ABIN387933 : Cai, Jin, Florens, Swanson, Kusch, Li, Workman, Washburn, Conaway, Conaway: The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN387933

  6. Chicken Polyclonal KAT5 Primary Antibody for WB - ABIN2779678 : Hejna, Holtorf, Hines, Mathewson, Hemphill, Al-Dhalimy, Olson, Moses: Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway. in The Journal of biological chemistry 2008 (PubMed)

  7. Chicken Polyclonal KAT5 Primary Antibody for IHC, WB - ABIN2780772 : Murr, Loizou, Yang, Cuenin, Li, Wang, Herceg: Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. in Nature cell biology 2006 (PubMed)

More Antibodies against K(lysine) Acetyltransferase 5 Interaction Partners

Fruit Fly (Drosophila melanogaster) K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. Heat Shock Factor recruits the dTip60 complex to the hsp70 loci in cells treated with salicylate, which triggers chromatin remodeling at these loci without transcription activation.

  2. Excess Tip60 exerts a neuroprotective role in axonal transport and functional locomotion defects in an animal model of Alzheimer's disease.

  3. a novel mechanism for Tip60 mediated sleep-wake regulation via control of axonal growth and PDF levels within the small ventrolateral neurons-encompassing neural network

  4. a functional interaction between Tip60 and APP (show APP Antibodies) in mediating nervous system development and apoptotic neuronal cell death

  5. The role of Tip60 HAT (show HAT Antibodies) activity in transcriptional control during multicellular development in vivo, was investigated.

  6. Ubiquitous dTip60 knock-down in flies was lethal, whereas knock-down in the wing imaginal disk led to developmental defects.

  7. demonstrated that the dTip60 chromatin-remodeling complex acetylates nucleosomal phospho-H2Av (show H2AFV Antibodies) and exchanges it with an unmodified H2Av (show H2AFV Antibodies); both the histone acetyltransferase (show HAT Antibodies) dTip60 and the atpase (show DNAH8 Antibodies) Domino/p400 (show EP400 Antibodies) catalyze the exchange of phospho-H2Av (show H2AFV Antibodies)

  8. TIP60 complex can promote the generation of silent chromatin.

  9. TIP60 is differentially expressed during Drosophila development, with transcript levels significantly peaking during embryogenesis, and is essential for multicellular development.

Human K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. Data suggest the combination of histone acetyltransferase TIP60 and microRNA miR (show MLXIP Antibodies)-22 as prognostic indicator of breast cancer progression.

  2. Colony-formation assays and soft agar assays show that gain of function of TIP60 or depletion of EDD1 in HPV-positive cervical cancer cells significantly inhibits cell growth in vitro

  3. We demonstrate for the first time that tumor suppressor Tip60 down-regulates cell adhesion and MT1-MMP (show MMP14 Antibodies) expression and thereby invasion of glioblastoma cells

  4. TIP60 relocalization to the chromatin to acetylates histone H4K16 and prevents the binding of 53BP1 (show TP53BP1 Antibodies) to its docking site.Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 (show TP53BP1 Antibodies) and RAP80 (show UIMC1 Antibodies) in Fanconi anemia (show PALB2 Antibodies).

  5. Our results revealed a major role of the KAT5-ATM (show ATM Antibodies) axis in protection of replicating chromatin against damage by the endogenous carcinogen FA.

  6. the acetylation-dependent NBS1 (show NBN Antibodies) turnover by TIP60 on damaged chromatin restricts the dispersal of NBS1 (show NBN Antibodies) foci from the sites of DNA damage.

  7. The stress-responsive gene ATF3 (show ATF3 Antibodies) regulates the histone acetyltransferase Tip60 stability by promoting USP7 (show USP7 Antibodies)-mediated deubiquitination of Tip60.

  8. Putative novel MYC (show MYC Antibodies) interactors include components of the STAGA/KAT5 and SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) chromatin remodeling complexes

  9. TIP60 interacted with H3K4me3 in response to TNF-alpha (show TNF Antibodies) signaling.

  10. Results establish that Tip60-T158 phosphorylation by p38 (show CRK Antibodies) plays an essential role in stimulating Tip60 activity required for inducing the p53 (show TP53 Antibodies)-PUMA (show BBC3 Antibodies) pathway that ultimately leads to apoptosis in response to DNA damage.

Mouse (Murine) K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. these results identify a new compaction pathway of mammalian pericentric heterochromatin relying on Tip60 that might be dependent on BRD2 (show BRD2 Antibodies) recruitment by H4K12 acetylation.

  2. The expression of putative SOX4 target genes during myoblast differentiation is specifically regulated by the molecular switching of the co-activator KAT5 and the co-repressor HDAC1 on SOX4 transcriptional activation.

  3. TIP60 K327 acetylation allows TIP60 to switch binding partners. conditional knockout in Treg cells results in autoimmune disease.

  4. Allele compensation in tip60+/- mice rescues white adipose tissue function in vivo.

  5. Tip60 hyperacetylates histone H4 in Ras-transformed cells.Tip60 coordinates histone acetylation at both local and global levels to facilitate Ras-induced transformation.

  6. RGS6 (show RGS6 Antibodies) suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 (show DNMT1 Antibodies) degradation and promoting apoptosis

  7. Early adipogenesis is regulated through USP7 (show USP7 Antibodies)-mediated deubiquitination of the histone acetyltransferase TIP60.

  8. SLX2 interacts with synaptonemal complex central element protein 2 (SYCE2 (show SYCE2 Antibodies)) and histone acetyltransferase TIP60.

  9. these results suggest that Tip60 binds with Pax6 (show PAX6 Antibodies) and that this physical interaction leads to the full-transcriptional activation of Pax6 (show PAX6 Antibodies) during retina development.

  10. Tip60 may function in a tumor suppressor pathway(s) to maintain adult cardiomyocytes in replicative senescence.

K(lysine) Acetyltransferase 5 (KAT5) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with KAT5

  • zgc:92510 (zgc:92510) antibody
  • K(lysine) acetyltransferase 5 (LOC100340634) antibody
  • CG6121 gene product from transcript CG6121-RA (Tip60) antibody
  • histone acetyltransferase Tip60 (Tip60) antibody
  • tip60 (AaeL_AAEL014072) antibody
  • tip60 (Smp_053140) antibody
  • HIV-1 tat interactive protein, homolog (human) (htatip) antibody
  • K(lysine) acetyltransferase 5 (KAT5) antibody
  • K(lysine) acetyltransferase 5 (Kat5) antibody
  • 6121 antibody
  • AI839539 antibody
  • CG6121 antibody
  • CPLA2 antibody
  • DmEG0007.7 antibody
  • Dmel/TIP60 antibody
  • Dmel\\CG6121 antibody
  • Dmel\\TIP60 antibody
  • dmHAG405 antibody
  • dTip60 antibody
  • EG0007.7 antibody
  • EG:EG0007.7 antibody
  • ESA1 antibody
  • Htatip antibody
  • Htatip1 antibody
  • im:6908768 antibody
  • PLIP antibody
  • TIP antibody
  • Tip55 antibody
  • Tip60 antibody
  • wu:fb55b08 antibody
  • ZC2HC5 antibody
  • zgc:110752 antibody

Protein level used designations for KAT5

K(lysine) acetyltransferase 5 , CG6121-PA , CG6121-PB , CG6121-PC , Tat-interactive protein , Tip60-PA , Tip60-PB , Tip60-PC , histone acetyltransferase Tip60 , tip60 , HIV-1 tat interactive protein , 60 kDa Tat-interactive protein , HIV-1 Tat interactive protein, 60kDa , K-acetyltransferase 5 , Tat interacting protein, 60kDa , cPLA(2)-interacting protein , cPLA2 interacting protein , histone acetyltransferase HTATIP , histone acetyltransferase KAT5 , HIV-1 tat interactive protein 1, 60 kDa homolog , HIV-1 tat interactive protein 1, homolog , Tat-interactive protein-60 , lysine acetyltransferase 5 , HIV-1 Tat interacting protein, 60kDa , HIV-1 Tat interactive protein 60 kD , HIV-1 Tat interactive protein, 60 kD , HIV-1 tat interactive protein, homolog , Histone acetyltransferase HTATIP

GENE ID SPECIES
436638 Danio rerio
100340634 Oryctolagus cuniculus
31362 Drosophila melanogaster
413101 Apis mellifera
5579231 Aedes aegypti
8344228 Schistosoma mansoni
503731 Danio rerio
10524 Homo sapiens
81601 Mus musculus
483728 Canis lupus familiaris
505619 Bos taurus
192218 Rattus norvegicus
451329 Pan troglodytes
100174410 Pongo abelii
Selected quality suppliers for anti-K(lysine) Acetyltransferase 5 (KAT5) Antibodies
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