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KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 Proteins (KDELR1)

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Additionally we are shipping KDELR1 Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KDELR1 10945 P24390
KDELR1 68137 Q99JH8
Rat KDELR1 KDELR1 361577 Q569A6
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Top KDELR1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KDELR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1) Interaction Partners

Human KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1) interaction partners

  1. KDELR protein mediated the intracellular trafficking of Japanese encephalitis virus particles.

  2. A Golgi-based KDELR-dependent signalling pathway controls invadopodia-dependent extracellular matrix degradation.

  3. We propose a model whereby in analogy to previous findings (e.g., the RAS-RAF (show RAF1 Proteins) signalling pathway), PHB (show PHB Proteins) can act as a signalling scaffold protein (show HOMER1 Proteins) to assist in KDELR-dependent Src (show SRC Proteins) activation

  4. It discuss the particular role of KDEL receptor signaling in the regulation of important pathways involved in the maintenance of the homeostasis of the transport apparatus, and in particular, of the Golgi complex.

  5. KDEL receptor activates CREB1 (show CREB1 Proteins) and other transcription factors that upregulate transport-related genes

  6. These findings reveal an unexpected GPCR-like mode of action of the KDEL-R and shed light on a core molecular control mechanism of intra-Golgi traffic.

  7. our data provide evidence that KDELR, as a novel inducer of autophagy, participates in the degradation of misfolded neurodegenerative disease-related proteins.

  8. Cystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors.

  9. the KDEL receptor participates in the ER stress response not only by its retrieval ability but also by modulating MAP kinase (show MAPK1 Proteins) signaling

  10. Src relocated the KDEL receptor (KDEL-R) from the Golgi apparatus to the endoplasmic reticulum

Mouse (Murine) KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1) interaction partners

  1. present a recessive mouse missense allele of the prototypical mammalian KDEL receptor, KDEL ER protein retention receptor 1 (KDELR1). Kdelr1 homozygous mutants were mildly lymphopenic, as were mice with a CRISPR/Cas9-engineered frameshift allele

  2. dilated cardiomyopathy found in the mutant KDEL receptor transgenic mice is associated with ER stress

KDELR1 Protein Profile

Protein Summary

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.

Gene names and symbols associated with KDELR1

  • KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (KDELR1)
  • KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (Kdelr1)
  • 8030486F04Rik protein
  • AW215843 protein
  • ERD2 protein
  • Erd2.1 protein
  • HDEL protein
  • PM23 protein

Protein level used designations for KDELR1

ER lumen protein retaining receptor 1 , KDEL endoplasmic reticulum protein retention receptor 1 , KDEL receptor 1 , putative MAPK-activating protein PM23

GENE ID SPECIES
10945 Homo sapiens
68137 Mus musculus
361577 Rattus norvegicus
618184 Bos taurus
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