KIAA1524 Proteins (KIAA1524)

Promotes anchorage-independent cell growth and tumor formation (By similarity).. Additionally we are shipping KIAA1524 Antibodies (67) and KIAA1524 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIAA1524 57650 Q8TCG1
KIAA1524 224171 Q8BWY9
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Top KIAA1524 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60 to 65 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 60 to 65 Days
$8,623.45
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Escherichia coli (E. coli) Human GST tag,His tag   100 μg Log in to see 15 to 18 Days
$720.00
Details

KIAA1524 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for KIAA1524 Interaction Partners

Human KIAA1524 interaction partners

  1. Membranous CIP2A expression as a potential novel prognostic and predictive indicator for tamoxifen resistance.

  2. Cip2a effectively promotes triple-negative breast cancer (TNBC) cell cycle progression and tumor growth via regulation of PP2A (show PPP2R4 Proteins)/c-myc (show MYC Proteins)/p27Kip1 (show CDKN1B Proteins) signaling, which could serve as a potential therapeutic target for TNBC patients.

  3. poor prognosis of chronic myeloid leukemia (show BCL11A Proteins) patients with high CIP2A levels is due to an antiapoptotic phenotype

  4. Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A (show PPP2R4 Proteins)/B56

  5. CIP2A is upregulated in MM, and CIP2A expression promotes cell proliferation and clonogenic formation ability by regulating the expression of AKT (show AKT1 Proteins) phosphorylation and c-Myc (show MYC Proteins).

  6. Gambogenic acid is a CIP2A inhibitor that interferes with the ubiquitination and destabilization of CIP2A.

  7. Silencing CIP2A enhanced CuB-induced growth inhibition.

  8. CIP2A copy number increase is associated with poor patient survival in human HNSCC.

  9. These results indicate that CIP2A modulates myeloma cell proliferation and apoptosis via PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling and suggest that it can potentially serve as a drug target for the treatment of multiple myeloma.

  10. CIP2A is involved in regulating multidrug resistance of cervical adenocarcinoma.

Mouse (Murine) KIAA1524 interaction partners

  1. CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A (show AURKA Proteins) during meiotic maturation in mouse oocytes

  2. Knockdown of CIP2A by stable CIP2A siRNA transfection inhibited MDA-MB-231 cell proliferation, invasion, colony growth in vitro, and xenograft growth and metastasis in vivo of breast cancer in mice.

  3. CIP2A as a hitherto unrecognized mediator of T-cell activation.

  4. Downregulation of CIP2A suppresses cell proliferation and growth of nasopharyngeal carcinoma.

  5. CIP2A strongly interacts with NEK2 (show NEK2 Proteins) during G2/M phase, thereby enhancing NEK2 kinase (show NEK2 Proteins) activity to facilitate centrosome separation in a PP1 (show PPP1CC Proteins)- and PP2A (show PPP2R2B Proteins)-independent manner.

  6. Data show that CIP2A expression can be systematically inhibited without severe consequences to normal mouse development and viability may have clinical relevance regarding targeting of oncogenic CIP2A for future cancer therapies.

  7. Loss of CIP2A in Myc (show MYC Proteins)-overexpressing neural progenitor cells significantly reduces the ability of Myc (show MYC Proteins) to increase self-renewal and proliferation.

KIAA1524 Protein Profile

Protein Summary

Promotes anchorage-independent cell growth and tumor formation (By similarity).

Gene names and symbols associated with KIAA1524 Proteins (KIAA1524)

  • KIAA1524 (KIAA1524)
  • cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog (cip2a.L)
  • cell proliferation regulating inhibitor of protein phosphatase 2A (CIP2A)
  • CONSTANS interacting protein 2a (CIP2a)
  • cell proliferation regulating inhibitor of protein phosphatase 2A (cip2a)
  • protein CIP2A homolog (LOC100222965)
  • RIKEN cDNA C330027C09 gene (C330027C09Rik)
  • AA408511 protein
  • AU018569 protein
  • Cip2a protein
  • Kiaa1524 protein
  • LOC100222895 protein
  • LOC100222965 protein
  • p90 protein

Protein level used designations for KIAA1524 Proteins (KIAA1524)

protein CIP2A homolog , KIAA1524 , CONSTANS interacting protein 2a , hypothetical protein LOC100216050 , cancerous inhibitor of PP2A , p90 autoantigen , protein CIP2A , p90 autoantigen homolog

GENE ID SPECIES
418410 Gallus gallus
494846 Xenopus laevis
705690 Macaca mulatta
741836 Pan troglodytes
778347 Solanum lycopersicum
100216050 Xenopus (Silurana) tropicalis
100222895 Taeniopygia guttata
100222965 Taeniopygia guttata
57650 Homo sapiens
538580 Bos taurus
224171 Mus musculus
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