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Involved in the generation of internal asymmetric signals required for neuronal polarization. Additionally we are shipping KIAA1598 Antibodies (3) and and many more products for this protein.
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Rnaset2 (show RNASET2 Proteins) inhibits melanocyte outgrowth through interacting with shootin1, and this effect may be associated with vitiligo (show MITF Proteins) pathogenesis.
these results point to a role of CDKL5 (show CDKL5 Proteins) in the early steps of neuronal differentiation that can be explained, at least in part, by its association with shootin1.
our data demonstrate the importance of the Shootin1/KIF20B interaction to the dynamic process of pyramidal neuronal polarization and migration.
Involved in the generation of internal asymmetric signals required for neuronal polarization. Acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. Accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization, its absence from the nascent axon's siblings by competition preventing the formation of surplus axons (By similarity).