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KLHDC8B encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Additionally we are shipping KLHDC8B Antibodies (47) and many more products for this protein.
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kelch protein KLHDC8B guards against mitotic errors, centrosomal amplification, and chromosomal instability
Deficiency of KLHDC8B leads to binucleated cells, implicating its involvement in Reed-Sternberg cell formation
Depletion of KLHDC8B through RNA interference leads to an increase in binucleated cells, implicating its reduced expression in the formation of classical Hodgkin lymphoma's signature Reed-Sternberg cell.
This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma.
kelch domain containing 8B
, kelch domain-containing protein 8B
, kelch domain-containing protein 8B-like