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anti-Keratin 8 (KRT8) Antibodies

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Additionally we are shipping Keratin 8 Proteins (44) and Keratin 8 Kits (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KRT8 3856 P05787
KRT8 16691 P11679
KRT8 25626 Q10758
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Top anti-Keratin 8 Antibodies at antibodies-online.com

Showing 10 out of 482 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-KRT8 Antibody Titration: 0.2-1 ug/mlPositive Control... Immunohistochemistry with Small intestine tissue at an antibody concen... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-KRT8 Antibody Titration: 0.2-1 ug/mlPositive Control... Immunohistochemistry with Small intestine tissue at an antibody concen... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Mouse Un-conjugated IHC (fro), IF, IHC (p), IP, WB   0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Hamster Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   50 μg Log in to see 6 to 8 Days
$357.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB Figure 1: Confocal immunofluorescence analysis of methanol-fixed ECA10... Figure 2: Immunohistochemical analysis of paraffin-embedded human brea... 100 μL Log in to see 3 to 4 Days
$442.20
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB   1 mL Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details

KRT8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Keratin 8 Antibodies

  1. Human Monoclonal KRT8 Primary Antibody for FACS, IHC (fro) - ABIN112173 : Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. in Cancer research 1990 (PubMed)
    Show all 13 references for ABIN112173

  2. Human Monoclonal KRT8 Primary Antibody for IHC (fro), IF - ABIN1106942 : Odin, Obrink: Quantitative determination of the organ distribution of the cell adhesion molecule cell-CAM 105 by radioimmunoassay. in Experimental cell research 1987 (PubMed)
    Show all 5 references for ABIN1106942

  3. Hamster Monoclonal KRT8 Primary Antibody for IHC (fro), IF - ABIN112171 : Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. in The Journal of pathology 1991 (PubMed)
    Show all 5 references for ABIN112171

  4. Human Polyclonal KRT8 Primary Antibody for IF, IHC (p) - ABIN197582 : Nakamichi, Hatakeyama, Nakayama: Formation of Mallory body-like inclusions and cell death induced by deregulated expression of keratin 18. in Molecular biology of the cell 2002 (PubMed)
    Show all 4 references for ABIN197582

  5. Human Monoclonal KRT8 Primary Antibody for FACS, IHC (fro) - ABIN112350 : Guelstein, Tchypysheva, Ermilova, Litvinova, Troyanovsky, Bannikov: Monoclonal antibody mapping of keratins 8 and 17 and of vimentin in normal human mammary gland, benign tumors, dysplasias and breast cancer. in International journal of cancer. Journal international du cancer 1988 (PubMed)
    Show all 4 references for ABIN112350

  6. Human Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN114674 : Waseem, Karsten, Leigh, Purkis, Waseem, Lane: Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability. in Biochemistry 2004 (PubMed)
    Show all 2 references for ABIN114674

  7. Cow (Bovine) Polyclonal KRT8 Primary Antibody for IHC, WB - ABIN2777112 : Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005 (PubMed)

  8. Human Monoclonal KRT8 Primary Antibody for ICC, IHC - ABIN969080 : Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast. in Cancer genetics and cytogenetics 2007 (PubMed)

  9. Chicken Polyclonal KRT8 Primary Antibody for IHC, WB - ABIN2777113 : Moon, Yau, Wright, Zahradka: Injury-induced expression of cytokeratins 8 and 18 by vascular smooth muscle cells requires concurrent activation of cytoskeletal and growth factor receptors. in Canadian journal of physiology and pharmacology 2008 (PubMed)

More Antibodies against Keratin 8 Interaction Partners

Human Keratin 8 (KRT8) interaction partners

  1. Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC (show UCN3 Antibodies))-induced phosphorylation of keratin 8 (K8) via ubiquitination of protein phosphatase 2 (PP2A (show PPP2R4 Antibodies)) through alpha4 phosphoprotein (show IGBP1 Antibodies) by caveolin-1 (cav-1 (show CAV1 Antibodies)).

  2. In human failing myocardium, where TNF-alpha (show TNF Antibodies) expression is upregulated, K8/K18 (show KRT18 Antibodies) were also ectopically expressed

  3. Human KRT8 variants promote acetaminophen induced hepatotoxicity in mouse models.

  4. Syndecan-1 (show SDC1 Antibodies) is involved in morphogenesis of the developing tooth crown and cervical loops, andntogether with CK8 and vimentin (show VIM Antibodies) in differentiation of preameloblasts and preodontoblasts.

  5. This is the first time intestinal cells have been suggested also functionally impaired by K8/K18 (show KRT18 Antibodies) mutations.

  6. Study indicates that Piwil2 (show PIWIL2 Antibodies) plays a role in Fas (show FAS Antibodies)-mediated apoptosis and can affect p53 (show TP53 Antibodies) phosphorylation in tumor cells, revealing a novel mechanism of Piwil2 (show PIWIL2 Antibodies) in apoptosis, and supports that Piwil2 (show PIWIL2 Antibodies) plays an active role in tumorigenesis.

  7. An increased expression of cytokeratin 8 and weak of calponin in tunica media of saphenous vein grafts might be useful markers of unfavorable long-term prognosis in CABG patients.

  8. These data support the idea that CK8 is an important receptor for Pet on epithelial cells for starting its cytotoxic effects.

  9. parkin (show PARK2 Antibodies) may inhibit cell growth, at least in part, by decreasing RPSA (show RPSA Antibodies) expression and inducing phosphorylation of cytokeratin 8/18

  10. These findings, along with the emerging role of cell surface CK8 in cancer metastasis, may imply a dual strategy for tumor cell survival in the host.

Pig (Porcine) Keratin 8 (KRT8) interaction partners

  1. This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 (show FAF1 Antibodies) and PTH1R (show PTH1R Antibodies) with some of leg weakness related traits in pigs.

  2. Mechanical injury of vascular smooth muscle up-regulated keratin 8.

Cow (Bovine) Keratin 8 (KRT8) interaction partners

  1. Results did not support that K8/K18 (show KRT18 Antibodies) filaments influence the expression of Fas (show FAS Antibodies) on the surface of luteal cells.

Mouse (Murine) Keratin 8 (KRT8) interaction partners

  1. Autoantibodies to several antigens were identified in 81% of K8-null male mice 8 mo or older. Similar autoantibodies were detected in aging K18 (show KRT18 Antibodies)-null male mice that had a related liver phenotype but normal colon compared with K8-null mice

  2. The regulation of the SCFA-MCT1 (show MCTS1 Antibodies)-HMGCS2 (show HMGCS2 Antibodies) axis is disrupted in K8(-/-) colonocytes, suggesting a role for keratins in colonocyte energy metabolism and homeostasis.

  3. In several liver stress models epiplakin and K8 genes displayed identical expression patterns and transgenic K8 overexpression resulted in elevated hepatic epiplakin levels.

  4. In human failing myocardium, where TNF-alpha (show TNF Antibodies) expression is upregulated, K8/K18 (show KRT18 Antibodies) were also ectopically expressed

  5. The findings demonstrate the near complete loss of K8/K18 (show KRT18 Antibodies) with concomitant high levels of vimentin (show VIM Antibodies) in CT26 (show DDX53 Antibodies) cells, a chemically-induced mouse colonic tumor.

  6. Directed expression of a chimeric type II keratin (show KRT80 Antibodies) partially rescues keratin 5 (show KRT36 Antibodies)-null mice.

  7. Keratin 8 is required for the maintenance of architectural structure in thymus epithelium.

  8. A conserved rod domain phosphotyrosine that is targeted by the phosphatase PTP1B (show PTPN1 Antibodies) promotes keratin 8 protein insolubility and filament organization.

  9. K8 acetylation at Lys (show LYZ Antibodies)-207, a highly conserved residue among type II keratins, is up-regulated upon hyperglycemia and down-regulated by SIRT2 (show SIRT2 Antibodies).

  10. Data indicate that cyclin D1 (show CCND1 Antibodies) is expressed exclusively in luminal keratin 8 immunoreactive tumor cells and is dependent on the adipose secreted hormone leptin (show LEP Antibodies).

Zebrafish Keratin 8 (KRT8) interaction partners

  1. Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.

Keratin 8 (KRT8) Antigen Profile

Protein Summary

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with anti-Keratin 8 (KRT8) Antibodies

  • keratin 8 (krt8) antibody
  • keratin 8 (KRT8) antibody
  • keratin 8 (Krt8) antibody
  • AA960620 antibody
  • AL022697 antibody
  • AU019895 antibody
  • Card2 antibody
  • cb186 antibody
  • CK-8 antibody
  • CK8 antibody
  • CYK8 antibody
  • CYKER antibody
  • DKFZp468F2127 antibody
  • DreK8 antibody
  • EndoA antibody
  • K2C8 antibody
  • K8 antibody
  • KERATIN8 antibody
  • KO antibody
  • Krt-2.8 antibody
  • krt2-5 antibody
  • krt2-8 antibody
  • KRT8 antibody
  • MGC69490 antibody
  • sb:cb186 antibody
  • wu:fa20h05 antibody
  • wu:fa95h10 antibody
  • wu:fb96c06 antibody
  • zf-K8 antibody
  • zfk8 antibody

Protein level used designations for anti-Keratin 8 (KRT8) Antibodies

keratin 8 , keratin complex 2, basic, gene 5 , cytokeratin 8 , cytokeratin-8 , keratin, type II cytoskeletal 8 , type-II keratin Kb8 , CK-8 , K8 , KERA , cytokeratin-A , keratin-8 , cytokeratin endo A , keratin complex 2, basic, gene 8 , etID33550.23 , etID43142.23 , etID43142.8 , keratin, type 2, gene 8

GENE ID SPECIES
431676 Xenopus (Silurana) tropicalis
693415 Macaca mulatta
697116 Macaca mulatta
700449 Macaca mulatta
737628 Pan troglodytes
743020 Pan troglodytes
100174430 Pongo abelii
100345306 Oryctolagus cuniculus
3856 Homo sapiens
100152077 Sus scrofa
281269 Bos taurus
101110495 Ovis aries
100348891 Oryctolagus cuniculus
16691 Mus musculus
25626 Rattus norvegicus
797433 Danio rerio
380217 Xenopus laevis
426896 Gallus gallus
486513 Canis lupus familiaris
Selected quality suppliers for anti-Keratin 8 (KRT8) Antibodies
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