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Ketohexokinase (KHK) ELISA Kits

KHK encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. Additionally we are shipping Ketohexokinase Antibodies (109) and Ketohexokinase Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KHK 16548 P97328
KHK 25659 Q02974
KHK 3795 P50053
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Top Ketohexokinase ELISA Kits at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 4.68 18.75 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for Ketohexokinase Interaction Partners

Mouse (Murine) Ketohexokinase (KHK) interaction partners

  1. Feedforward upregulation of fructolytic and gluconeogenic enzymes specifically requires GLUT5 (show SLC2A5 ELISA Kits) and KHK and may proactively enhance the intestine's ability to process anticipated increases in dietary fructose concentrations.

  2. Significant levels of blood fructose are maintained independent of dietary fructose, KHK, and GLUT5 (show SLC2A5 ELISA Kits), probably by endogenous synthesis of fructose.

  3. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (show HIF1A ELISA Kits)) activation of SF3B1 (show SF3B1 ELISA Kits) and SF3B1 (show SF3B1 ELISA Kits)-mediated splice switching of KHK-A to KHK-C

  4. Fructokinase-knockout mice with delayed hydration were protected from renal injury. Thus, recurrent dehydration can induce renal injury via a fructokinase-dependent mechanism, likely from the generation of endogenous fructose via the polyol pathway.

  5. This study demonstrates that blocking KHK and redirecting fructose metabolism to alternative pathways is an effective way to prevent visceral obesity and insulin (show INS ELISA Kits) resistance induced by high fructose, a widespread component of Western diets.

  6. These studies identify fructokinase as a novel mediator of diabetic nephropathy and document a novel role for endogenous fructose production, or fructoneogenesis, in driving renal disease.

  7. High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.

  8. Fructose-induced metabolic syndrome is prevented in mice lacking both fructokinase B and A but is exacerbated in mice lacking fructokinase A.

  9. These studies are the first demonstration that neither Khk isoform is required for normal growth and development.

Human Ketohexokinase (KHK) interaction partners

  1. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (show HIF1A ELISA Kits)) activation of SF3B1 and SF3B1-mediated splice switching of KHK-A to KHK-C

  2. These studies identify fructokinase as a novel mediator of diabetic nephropathy and document a novel role for endogenous fructose production, or fructoneogenesis, in driving renal disease.

  3. This study determined if single nucleotide polymorphisms in genes involved in fructose transport,SLC2A2 (show SLC2A2 ELISA Kits) and SLC2A5 (show SLC2A5 ELISA Kits) and metabolism, etohexokinase affect inter-individual variability in metabolic phenotypes.

  4. In human hepatocytes uric acid up-regulates KHK expression thus leading to the amplification of the lipogenic effects of fructose.

  5. ketohexokinase-A serves an unknown physiologic function that remains intact in essential fructosuria.

  6. The expression of ketohexokinase is diminished in human clear cell type of renal cell carcinoma

  7. Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells.

  8. The structure of the KHK-A ternary complex revealed an active site with fructose & the ATP analogue in positions ready for phosphorylation. The effects of the pathogenic mutations Gly40Arg & Ala43Thr have been modelled in the context of the KHK structure.

Ketohexokinase (KHK) Antigen Profile

Antigen Summary

This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Ketohexokinase (KHK) ELISA Kits

  • ketohexokinase-like (LOC100055449) antibody
  • ketohexokinase (khk) antibody
  • ketohexokinase (KHK) antibody
  • ketohexokinase (Hhal_0921) antibody
  • ketohexokinase (AaeL_AAEL006316) antibody
  • Ketohexokinase (Nwat_0240) antibody
  • Ketohexokinase (khk) antibody
  • ketohexokinase (LOC100351729) antibody
  • ketohexokinase (Khk) antibody
  • ketohexokinase (fructokinase) (KHK) antibody
  • ketohexokinase-like (LOC100523241) antibody
  • KETHPRO antibody
  • khk antibody
  • wu:fj68h03 antibody
  • zgc:92219 antibody
  • zgc:92626 antibody

Protein level used designations for Ketohexokinase (KHK) ELISA Kits

ketohexokinase , Ketohexokinase , hepatic fructokinase

GENE ID SPECIES
100055449 Equus caballus
436909 Danio rerio
698328 Macaca mulatta
4710193 Halorhodospira halophila SL1
5567860 Aedes aegypti
9391692 Nitrosococcus watsonii C-113
100306748 Salmo salar
100351729 Oryctolagus cuniculus
16548 Mus musculus
25659 Rattus norvegicus
3795 Homo sapiens
100170647 Canis lupus familiaris
614868 Bos taurus
100447147 Pongo abelii
100523241 Sus scrofa
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