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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteins (KIR2DL1)

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Antibodies (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIR2DL1 3802 P43626
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Top Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details

KIR2DL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , , ,

Top referenced Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteins

  1. Human KIR2DL1 Protein expressed in Human Cells - ABIN2005486 : Fan, Long, Wiley: Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. in Nature immunology 2001 (PubMed)

More Proteins for Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) interaction partners

  1. Influence of Differently Licensed KIR2DL1-Positive Natural Killer Cells in Transplant Recipients with Acute Leukemia

  2. Educated natural killer cells expressing KIR2DL1 display functional advantage for anti-HIV-1 antibody-dependent activation.

  3. KIR2DL1*022 and 2DL1*026 evolved in the KhoeSan after their divergence from other modern human populations.

  4. Data suggest regulatory interactions between major histocompatibility antigen HLA-C and killer cell Ig-like receptor (KIR) might promote Graft-versus-Leukemia effects following transplantation.

  5. Coengagement of inhibitory receptors, either KIR2DL1 or CD94 (show KLRD1 Proteins)-NKG2A (show KLRC1 Proteins), did not inhibit phosphorylation of Stat5 (show STAT5A Proteins) but inhibited selectively phosphorylation of Akt (show AKT1 Proteins) and S6 ribosomal protein (show RPS6 Proteins).

  6. genetic association studies in Chinese Han population: Data suggest that the frequency of KIR2DL1 gene is increased in women with pre-eclampsia when homozygous HLA-C2 allele appears in the fetus.

  7. Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (KIR) genes.

  8. These results revealed that ITIM phosphorylation is controlled by self-association of KIR (show GEM Proteins) and that His-36 serves as a gatekeeper to prevent unregulated signaling through KIR2DL1.

  9. C2 of KIR2DL1 is a novel risk factor, and homozygosity for C1 is a protective factor for childhood B-ALL

  10. We investigated the association of HLA alleles and KIR ligands according to oligoclonal band status in multiple sclerosis patients.

Pig (Porcine) Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) interaction partners

  1. The first and possibly only KIR (show GEM Proteins) gene, named KIR2DL1, in Sus scrofa was identified.

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Protein Profile

Protein Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DL1

  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR2DL1)
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A (KIR2DL5A)
  • CD158A protein
  • KIR-K64 protein
  • KIR2DL1 protein
  • KIR2DL4 protein
  • KIR221 protein
  • NKAT protein
  • NKAT1 protein
  • p58.1 protein

Protein level used designations for KIR2DL1

CD158 antigen-like family member A , MHC class I NK cell receptor , NKAT-1 , killer Ig receptor , killer cell immunoglobulin-like receptor 2DL1 , killer inhibitory receptor 2-2-1 , natural killer-associated transcript 1 , p58 NK cell inhibitory receptor NKR-K6 , p58 NK receptor CL-42/47.11 , p58 killer cell inhibitory receptor KIR-K64 , p58 natural killer cell receptor clones CL-42/47.11 , p58.1 MHC class-I-specific NK receptor , killer cell immunoglobulin-like receptor 2DL5A , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5

GENE ID SPECIES
3802 Homo sapiens
282860 Bos taurus
100127456 Sus scrofa
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