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Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) ELISA Kits

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009].. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Antibodies (34) and Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KLRF1 KLRF1 51348 Q9NZS2
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More ELISA Kits for Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) interaction partners

  1. IL-15 (show IL15 ELISA Kits)+IL-12 (show IL12A ELISA Kits) has an immunomodulatory effect on NK cell subsets from HIV-infected individuals viz down-regulation of iNKRs, elevation of activatory receptors NKp46 (show NCR1 ELISA Kits) and NKG2D (show KLRK1 ELISA Kits), and induction of coreceptor NKp80.

  2. our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL (show CLEC2B ELISA Kits) axis.

  3. Two non-consensus amino acids of NKp80, in particular arginine 6, critically impair both hemi-immunoreceptor tyrosine-based activation motif phosphorylation and Syk (show SYK ELISA Kits) recruitment.

  4. Activating receptor NKp80 induces cytotoxicity by using an atypical hemi-ITAM amino acid seqeuence and the Syk (show SYK ELISA Kits)-kinase pathway.

  5. NKp80 is expressed on a highly responsive subset of effector memory CD8 (show CD8A ELISA Kits) T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL (show CLEC2B ELISA Kits)-expressing cells.

Chimpanzee Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) interaction partners

  1. phenotypic, molecular, and functional characterization for triggering molecules (NKp46 (show NCR1 ELISA Kits), NKp30 (show NCR3 ELISA Kits) NKp80, and NKG2D (show KLRK1 ELISA Kits); in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 and particularly NKp30 (show NCR3 ELISA Kits)

Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) Antigen Profile

Antigen Summary

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009

Gene names and symbols associated with KLRF1

  • killer cell lectin-like receptor subfamily F, member 1 (KLRF1) antibody
  • killer cell lectin-like receptor subfamily F, member 1-like (LOC613393) antibody
  • CLEC5C antibody
  • KLRF1 antibody
  • MGC152582 antibody
  • NKp80 antibody

Protein level used designations for KLRF1

C-type lectin domain family 5 member C , activating coreceptor NKp80 , killer cell lectin-like receptor F1 , killer cell lectin-like receptor subfamily F member 1 , lectin-like receptor F1 , killer cell lectin-like receptor subfamily F, member 1 , NKp80 receptor

GENE ID SPECIES
51348 Homo sapiens
465281 Pan troglodytes
574389 Macaca mulatta
611429 Canis lupus familiaris
613393 Bos taurus
784491 Bos taurus
100144592 Sus scrofa
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