anti-Kinesin Family Member 11 (KIF11) Antibodies

KIF11 encodes a motor protein that belongs to the kinesin-like protein family. Additionally we are shipping KIF11 Kits (5) and KIF11 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KIF11 3832 P52732
KIF11 16551 Q6P9P6
KIF11 171304  
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Top anti-KIF11 Antibodies at antibodies-online.com

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, IP 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO205 cells, using KIF11/Eg5 (Phospho-Thr926) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of KIF11 Antibody (N-term) (ABIN653041) in CHO cell line lysates (35 µg/lane). KIF11 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with KIF11 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat/HepG2/COS cells, using KIF11/Eg5 (Ab-927) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using KIF11/Eg5 (Ab-927) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ICC, IF, IP, WB Hela cell extract (Lane 1) or NIH3T3 cell extract (Lane 2) was resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Eg5 (Clone 10C7/Eg5) antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of Eg5 on a human endothelial cell lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the anti- human Eg5 antibody. Immunofluorescence staining of A431 cells. 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Eg5 Antibody [NBP1-84888] - Staining of human duodenum shows strong nuclear, membranous and cytoplasmic positivity in glandular cells. Western Blot: Eg5 Antibody [NBP1-84888] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401441) 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Eg5 Antibody [NBP1-84887] - Staining of human cell line A-431 shows positivity in cytoplasm. Immunohistochemistry-Paraffin: Eg5 Antibody [NBP1-84887] - Staining of human testis shows strong cytoplasmic positivity in cells of seminiferus ducts. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details

KIF11 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-KIF11 Antibodies

  1. Human Monoclonal KIF11 Primary Antibody for ICC, IF - ABIN256473 : Bartoli, Jakovljevic, Woolford, Saunders: Kinesin molecular motor Eg5 functions during polypeptide synthesis. in Molecular biology of the cell 2011 (PubMed)
    Show all 5 references for 256473

  2. Human Monoclonal KIF11 Primary Antibody for IF, WB - ABIN968406 : Blangy, Lane, dHérin, Harper, Kress, Nigg: Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. in Cell 1996 (PubMed)
    Show all 2 references for 968406

  3. Human Monoclonal KIF11 Primary Antibody for IP, WB - ABIN1449288 : Brown: Sphingolipid organization in biomembranes: what physical studies of model membranes reveal. in Journal of cell science 1998 (PubMed)
    Show all 2 references for 1449288

  4. Human Polyclonal KIF11 Primary Antibody for IF, IHC - ABIN1532702 : Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: The DNA sequence and comparative analysis of human chromosome 10. ... in Nature 2004 (PubMed)
    Show all 2 references for 1532702

  5. Human Polyclonal KIF11 Primary Antibody for ICC, IF - ABIN4307153 : Wissing, De Morrée, Dezentjé, Buijs, De Krijger, Smit, Van Weerden, Gelderblom, van der Pluijm: Nuclear Eg5 (kinesin spindle protein) expression predicts docetaxel response and prostate cancer aggressiveness. in Oncotarget 2014 (PubMed)

  6. Human Polyclonal KIF11 Primary Antibody for FACS, IHC (p) - ABIN653041 : Parke, Wojcik, Kim, Worthylake: ATP hydrolysis in Eg5 kinesin involves a catalytic two-water mechanism. in The Journal of biological chemistry 2010 (PubMed)

  7. Human Monoclonal KIF11 Primary Antibody for IF, IP - ABIN1449287 : Le Guellec, Paris, Couturier, Roghi, Philippe: Cloning by differential screening of a Xenopus cDNA that encodes a kinesin-related protein. in Molecular and cellular biology 1991 (PubMed)

  8. Human Polyclonal KIF11 Primary Antibody for ICC, IF - ABIN4307152 : Kuga, Nie, Kazami, Satoh, Matsushita, Nomura, Maeshima, Nakayama, Tomonaga: Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation. in Oncogenesis 2014 (PubMed)

More Antibodies against KIF11 Interaction Partners

Human Kinesin Family Member 11 (KIF11) interaction partners

  1. Progressive retinal degeneration in KIF11-related retinopathy indicates a role for KIF11 not only in ocular development but also in maintaining retinal morphology and function. The remarkable variability of the ocular phenotype suggests four different types of retinopathy which may overlap.

  2. Among the detected mutations, LRP5 (show LRP5 Antibodies) accounted for the largest proportion with a mean mutation rate of 16.1% (5/31, 16.1%), followed by NDP (show NDP Antibodies) (3/31, 9.7%), FZD4 (show FZD4 Antibodies) (2/31, 6.5%), TSPAN12 (show TSPAN12 Antibodies) (1/31, 3.2%), and KIF11 (1/31, 3.2%). All the novel changes were predicted to be pathogenic by a series of bioinformatics analyses.

  3. Data show that the kinesin 5 (Eg5) binding time has less sensitivity on MCF7 as compared to bovine brain microtubules.

  4. mixing of Eg5 and MTs (show TIMM8A Antibodies) produced a range of spatiotemporal dynamics

  5. that Pten (show PTEN Antibodies), through the Dlg1 (show DLG1 Antibodies)-binding ability of its PDZ (show INADL Antibodies)-binding domain , accumulates phosphorylated Eg5 at duplicated centrosomes to establish symmetrical bipolar spindles that properly segregate chromosomes

  6. KIF11 is an important regulator of activity in oesophageal and colorectal tumor stem cells.

  7. Levels of phosphorylated Erk1/2 (show MAPK1/3 Antibodies) were lower in KIF11 siRNA-transfected cells than with negative-control siRNA-transfected cells. These results indicate that KIF11 is involved in intestinal mucin (show SLC13A2 Antibodies) phenotype gastric cancer.

  8. Patients with KIF11 mutations show a specific ocular phenotype with variable expressivity and intrafamilial variability. Macular atrophy and dysfunction have not been consistently documented before.

  9. This stuidy demonstrated that overexpression of Eg5 associates with high-grade astrocytic neoplasm.

  10. Data show that kinesin spindle protein Eg5 inhibitor LY2523355 has broad target-mediated anticancer activity in vitro and in vivo.

Pig (Porcine) Kinesin Family Member 11 (KIF11) interaction partners

  1. Data suggest that poleward transport of TPX2, which requires dynein and Eg5, down-regulates its microtubule nucleating activity near kinetochores and links microtubules to dynein for incorporation into the spindle.

Mouse (Murine) Kinesin Family Member 11 (KIF11) interaction partners

  1. that Pten (show PTEN Antibodies), through the Dlg1 (show DLG1 Antibodies)-binding ability of its PDZ (show INADL Antibodies)-binding domain , accumulates phosphorylated Eg5 at duplicated centrosomes to establish symmetrical bipolar spindles that properly segregate chromosomes

  2. Fbxo30 (show FBXO30 Antibodies)-Eg5 interaction as a critical checkpoint in mammopoiesis.

  3. Data show that the STIM1 (show STIM1 Antibodies) Ksp (Eg5)-cre knockout mice produced more urine compared to control.

  4. Data suggest that amyloid-beta (here, Abeta 1-42) induces acute and chronic synaptic dysfunction in part through inhibition of Eg5 (kinesin-5) in hippocampal neurons.

  5. Disruption of the in vivo interaction of KIF11 with ZBP1 (show ZBP1 Antibodies) delocalizes beta-actin (show ACTB Antibodies) mRNA and affects cell migration.

  6. These results suggest that 4-(N-(2-(N-acetylcysteine-S-yl) acetyl) amino)-4'- (N-(2-(N-(triphenylmethyl)amino)acetyl)amino)azobenzene could be used as photochromic inhibitor of Eg5 to achieve photocontrol of living cells.

  7. incorporation of photochromic molecules into the key region of loop L5 facilitates the photocontrol of the function of kinesin Eg5.

  8. Finally, when kinesin spindle protein (KSP) siRNA was encapsulated in lipid nanoparticles containing a modest amount of PEG (show PAEP Antibodies), the proliferation of endothelial cells was inhibited due to the efficient knock down of KSP mRNA.

  9. These results show that intratumoral electro-transfer of siRNA is feasible and kinesin spindle protein (KSP)-specific siRNA may provide a novel strategy for therapeutic intervention.

  10. observations explain the poleward accumulation of Eg5 in early mitosis and its redistribution in anaphase. Inhibition of dynein blocked Eg5 movement on microtubules, whereas depletion of the Eg5-binding protein TPX2 (show DAZL Antibodies) resulted in end-directed Eg5 movement.

Cow (Bovine) Kinesin Family Member 11 (KIF11) interaction partners

  1. Data show that the kinesin 5 (Eg5) binding time has less sensitivity on MCF7 as compared to bovine brain microtubules.

KIF11 Antigen Profile

Protein Summary

This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.

Gene names and symbols associated with KIF11

  • kinesin family protein (AT2G36200) antibody
  • kinesin family member 11 (kif11) antibody
  • kinesin family member 11 (KIF11) antibody
  • kinesin family member 11 (Kif11) antibody
  • DDBDRAFT_0189194 antibody
  • DDBDRAFT_0201556 antibody
  • DDB_0189194 antibody
  • DDB_0201556 antibody
  • Eg5 antibody
  • F2H17.19 antibody
  • F2H17_19 antibody
  • HKSP antibody
  • Kif8 antibody
  • Kifl1 antibody
  • Knsl1 antibody
  • MCLMR antibody
  • TRIP5 antibody

Protein level used designations for KIF11

TR-interacting protein 5 , TRIP-5 , kinesin-like protein 1 , kinesin-like protein KIF11 , kinesin-like spindle protein HKSP , kinesin-related motor protein Eg5 , thyroid receptor-interacting protein 5 , kinesin 11 , kinesin-like 1

GENE ID SPECIES
818192 Arabidopsis thaliana
8627935 Dictyostelium discoideum AX4
3832 Homo sapiens
100526080 Sus scrofa
16551 Mus musculus
171304 Rattus norvegicus
423809 Gallus gallus
477769 Canis lupus familiaris
508467 Bos taurus
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