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Kruppel-Like Factor 11 Proteins (KLF11)

The protein encoded by KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. Additionally we are shipping KLF11 Antibodies (82) and KLF11 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KLF11 8462 O14901
KLF11 194655 Q8K1S5
Rat KLF11 KLF11 313994  
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Top KLF11 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

KLF11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Kruppel-Like Factor 11 (KLF11) Interaction Partners

Human Kruppel-Like Factor 11 (KLF11) interaction partners

  1. Results suggest a role for KLF11 in upregulating MAO-A (show MAOA Proteins) in depressive disorder and chronic social stress, suggesting that inhibition of the pathways regulated by this transcription factor may aid in the therapeutics of neuropsychiatric illnesses

  2. The data suggest a relationship between promoter DNA methylation (show HELLS Proteins) and KLF11 gene expression in ovarian cancer tumorigenesis.

  3. identified an evolutionarily conserved metabolic regulator, Kruppel-like factor 11 (KLF11), as a novel browning transcription factor in human adipocytes that is required for rosiglitazone-induced browning.

  4. KLF11 repressed most endometrial CYP (show PPIG Proteins) enzymes

  5. Levels of KLF11 are significantly increased in the postmortem prefrontal cortex of subjects with alcohol dependence compared to controls.

  6. KLF11 regulates distinct gene networks.

  7. KLF111 represses glycodelin-A (show PAEP Proteins) levels and influences its role in the ovarian endometrium.

  8. KLF11 is a critical transcription factor in the function of mesenchymal cells and, specifically, as a negative regulator of collagen secretion.

  9. Data identify a novel pathogenic role for KLF11 in preventing de novo disease-associated fibrosis in endometriosis.

  10. The A347S mutation disrupted KLF11-mediated increases in basal insulin (show INS Proteins) levels and promoter activity and blunted glucose-stimulated insulin (show INS Proteins) secretion.

Mouse (Murine) Kruppel-Like Factor 11 (KLF11) interaction partners

  1. Results suggest a role for KLF11 in upregulating MAO-A (show MAOA Proteins) in depressive disorder and chronic social stress, suggesting that inhibition of the pathways regulated by this transcription factor may aid in the therapeutics of neuropsychiatric illnesses

  2. Data show that the major phenotype given by the whole-body deletion of Kruppel-like factor 11 (Klf11) is not diabetes but increased insulin (show INS Proteins) sensitivity.

  3. Loss of KLF11 expression is associated with hyperglycemia in Type 2 diabetes.

  4. this study revealed a new role for the KLF11 gene in the mechanisms underlying the antinociceptive effects of chronic ethanol exposure

  5. KLF11 is a critical transcription factor in the function of mesenchymal cells and, specifically, as a negative regulator of collagen secretion.

  6. Taken together, our findings identify a novel anti-hypertrophic and anti-fibrotic role of KLF11, and KLF11 activator may serve as candidate drug for heart failure patients.

  7. Overexpression of KLF11 in the livers of diabetic and obese mice activates the PPARalpha (show PPARA Proteins) signaling pathway, subsequently markedly improving the fatty liver phenotype. Knockdown of KLF11 increases hepatic triglycerides.

  8. Data identify a novel pathogenic role for KLF11 in preventing de novo disease-associated fibrosis in endometriosis.

  9. Recruitment of KLF11 as a novel co-regulator (with peroxisome proliferator-activated receptor PPARgamma (show PPARG Proteins)) plays a critical role in cerebrovascular protection after ischemic insults.

  10. Kruppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-kappaB signaling pathway.

KLF11 Protein Profile

Protein Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with Kruppel-Like Factor 11 Proteins (KLF11)

  • Kruppel-like factor 11 (KLF11)
  • Kruppel-like factor 11 (klf11)
  • Kruppel-like factor 11 (LOC100194692)
  • Kruppel-like factor 11 (Klf11)
  • Kruppel-like factor 11a (klf11a)
  • 9830142A17 protein
  • D12Ertd427e protein
  • FKLF protein
  • FKLF1 protein
  • klf11 protein
  • MGC145216 protein
  • MODY7 protein
  • si:dkey-81b15.5 protein
  • Tcfcp2l2 protein
  • Tieg2 protein
  • Tieg2b protein
  • Tieg3 protein
  • wu:fc45c07 protein
  • wu:fj44b12 protein
  • zgc:153255 protein

Protein level used designations for Kruppel-Like Factor 11 Proteins (KLF11)

Kruppel-like factor 11 , novel kruppel-like factor family protein , krueppel-like factor 11-like , Krueppel-like factor 11-like , Krueppel-like factor 11 , TGFB-inducible early growth response protein 2 , TIEG-2 , transforming growth factor-beta-inducible early growth response protein 2 , TGFB inducible early growth response 2 , TGFB inducible early growth response 3 , TGFB-inducible early growth response protein 2b , TGFB-inducible early growth response protein 3 , TIEG-3 , transforming growth factor-beta-inducible early growth response protein 3 , transcription factor CP2-like 2 , TIEG2 , TGF-beta inducible early growth response protein 2

GENE ID SPECIES
459023 Pan troglodytes
702323 Macaca mulatta
733909 Xenopus (Silurana) tropicalis
100031998 Monodelphis domestica
100194692 Salmo salar
100436340 Pongo abelii
100465756 Ailuropoda melanoleuca
100607386 Nomascus leucogenys
8462 Homo sapiens
421934 Gallus gallus
100174954 Sus scrofa
194655 Mus musculus
444439 Xenopus laevis
313994 Rattus norvegicus
560787 Danio rerio
475665 Canis lupus familiaris
616730 Bos taurus
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