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human homolog is a transcription factor\; involved in haematopoietic differentiation [RGD, Feb 2006].. Additionally we are shipping KLF3 Antibodies (40) and many more products for this protein.
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Among the mechanosensitive genes, the two transcription factors, HoxA5 (show HOXA5 Proteins) and Klf3, contain cAMP-response-elements methylation of which could serve as a mechanosensitive master switch in gene expression in atherosclerosis. (Review)
Klf-3 expression is downregulated in human metastatic sarcomas, and Klf-3 levels negatively correlate with miR (show MLXIP Proteins)-182 expression.
A feedback loop consisting of microRNA 23a/27a and the beta-like globin suppressors KLF3 and SP1 regulates globin gene expression.
B cell differentiation is significantly impaired in the bone marrow, spleen, and peritoneal cavity of Klf3 null mice; the defects are cell autonomous.
Low KLF3 is associated with acute myeloid leukemia (show BCL11A Proteins).
KLF3 is an important regulator of several biological processes, including adipogenesis, erythropoiesis, and B cell development. (Review)
The recruitment of CtBP (show CTBP2 Proteins) and sumoylation are required for full repression by BKLF.
Cineromycin B inhibited adipocyte differentiation in 3T3-L1 cells mainly via upregulation of KLF2 (show KLF2 Proteins) and KLF3 mRNA expression at an early stage of the differentiation.
Phosphorylation of KLF3 and CtBP2 (show CTBP2 Proteins) by HIPK2 (show HIPK2 Proteins) strengthens the interaction between these two factors and increases transcriptional repression by KLF3.
KLF3 acts as transcriptional repressor for the leukocyte-specific integrin beta7 (Itgb7 (show ITGB7 Proteins), Ly69 (show ITGB7 Proteins)) by binding to the beta7 promoter, as revealed by chromatin immunoprecipitation.
We conclude that KLF3 plays diverse and important roles in cardiovascular development and function in mice.
KLF3 binds the Fam132a promoter in vitro and in vivo and that this leads to repression of promoter activity. Fam132a is significantly upregulated in the absence of KLF3.
KLF3 and KLF8 have overlapping roles in vivo and participate in the silencing of embryonic globin expression during development.
IL-17 (show IL17A Proteins) suppresses expression of PPARgamma (show PPARG Proteins), C/EBPalpha (show CEBPA Proteins), KLF15, a pro-adipogenic transcription factor, and enhances expression of KLF2 (show KLF2 Proteins) and KLF3, which are anti-adipogenic.
KLF3 is a feedback repressor that counters the activity of EKLF (show KLF1 Proteins) at selected target genes to achieve normal erythropoiesis
we concluded that KLF3 is a transcriptional repressor for wee1 (show WEE1 Proteins) gene.
KLF3 is a driving force toward marginal zone B-cell maturation (show TNFRSF17 Proteins).
human homolog is a transcription factor\; involved in haematopoietic differentiation
Krueppel-like factor 3
, CACCC-box-binding protein BKLF
, basic Kruppel-like factor
, basic krueppel-like factor
, basic kruppel like factor
, transcript ch138
, Basic Kruppel- like factor
, Kruppel-like factor 12