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Kv Channel Interacting Protein 4 Proteins (KCNIP4)

KCNIP4 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Additionally we are shipping Kv Channel Interacting Protein 4 Antibodies (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNIP4 80333 Q6PIL6
KCNIP4 80334 Q6PHZ8
KCNIP4 259243 Q99MG9
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Top Kv Channel Interacting Protein 4 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,641.83
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,641.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,641.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KCNIP4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Kv Channel Interacting Protein 4 (KCNIP4) Interaction Partners

Human Kv Channel Interacting Protein 4 (KCNIP4) interaction partners

  1. Subunit counting by single-molecule imaging revealed that the bound number of KChIP4 in each Kv4.2 (show KCND2 Proteins).KChIP4 complex was dependent on the expression level of KChIP4.

  2. genetic association studies in populations in Germany: Data suggest that multiple SNPs in KCNIP4 are associated not only with attention deficit disorder with hyperactivity in children and adults but also with personality disorders.

  3. Genome-wide association study identifies KCNIP4 as an asthma gene in human and in mouse.

  4. KChIP4a suppresses A-type Kv4 (show KCNC1 Proteins) current via ER retention and enhancement of Kv4 (show KCNC1 Proteins) closed-state inactivation.

  5. The synthesis of the variant KCNIP4 isoform is also detrimental to brain physiology, as it results in the concomitant blockade of the fast kinetics of potassium channels.

  6. These data demonstrate that PKA phosphorylation of Kv4.2 (show KCND2 Proteins) plays an important role in the trafficking of Kv4.2 (show KCND2 Proteins) through its specific interaction with KChIP4a.

  7. cloning and investigation of interaction with presenilin 2 (show PSEN2 Proteins) and voltage-gated potassium channel subunit Kv4 (show KCNC1 Proteins)

  8. The conformational change with metal-bound KChIP4.1 is crucial for its interaction with Kv channel but not for KChIP2.2, and that the Mg2 (show MUC7 Proteins)+- and Ca2 (show CA2 Proteins)+-binding properties of KChIP2.2 and KChIP4.1 have different effects on their molecular structure.

  9. Mutation of KCNIP4 is associated with renal cell carcinoma (show MOK Proteins).

  10. CALP and calsenilin (show KCNIP3 Proteins) are involved in the trafficking of Golgi glycosyltransferases.

Mouse (Murine) Kv Channel Interacting Protein 4 (KCNIP4) interaction partners

  1. Genome-wide association study identifies KCNIP4 as an asthma gene in human and in mouse.

  2. KChIP4a functions to promote tetrameric assembly and enhance surface expression of Kv4 (show KCNC1 Proteins) channels.

  3. These data demonstrate that PKA phosphorylation of Kv4.2 (show KCND2 Proteins) plays an important role in the trafficking of Kv4.2 (show KCND2 Proteins) through its specific interaction with KChIP4a.

  4. KChIP4 was highly expressed by neurons in layers II-IV of cortex and in hippocampus, thalamus and the Purkinje cell layer of the cerebellum.

  5. Surface expression of Kv4 (show KCNC1 Proteins) complexes may thus be controlled by an auto-inhibitory domain in the KChIP subunit.

  6. N-terminal binding of Kv4.3 (show KCND3 Proteins) to the core of KChIP4a mobilizes the KChIP4a N terminus, which serves as the slow inactivation gate.

Kv Channel Interacting Protein 4 (KCNIP4) Protein Profile

Protein Summary

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with KCNIP4

  • Kv channel interacting protein 4 (KCNIP4)
  • Kv channel interacting protein 4 (kcnip4)
  • Kv channel interacting protein 4 (LOC100348464)
  • Kv channel interacting protein 4 (Kcnip4)
  • AV032399 protein
  • Calp protein
  • Calp250 protein
  • DKFZp459M1362 protein
  • Kchip4 protein
  • KCHIP4.2 protein
  • KChIP4a protein
  • KCNIP4 protein
  • MGC115522 protein

Protein level used designations for KCNIP4

Kv channel interacting protein 4 , Kv channel-interacting protein , Kv channel-interacting protein 4 , a-type potassium channel modulatory protein 4 , calsenilin-like protein , potassium channel interacting protein 4 , potassium channel-interacting protein 4 , KChIP4 , A-type potassium channel modulatory protein 4

GENE ID SPECIES
395239 Gallus gallus
471155 Pan troglodytes
734586 Xenopus laevis
100174291 Pongo abelii
100348464 Oryctolagus cuniculus
80333 Homo sapiens
479129 Canis lupus familiaris
614299 Bos taurus
80334 Mus musculus
259243 Rattus norvegicus
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