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Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.. Additionally we are shipping LIM Homeobox 5 Antibodies (51) and LIM Homeobox 5 Kits (10) and many more products for this protein.
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discrete enhancer elements control lhx5 expression in different regions of the forebrain.
Lhx5 is a required factor that promotes forebrain development and inhibits Wnt (show WNT2 Proteins) signaling by activating the transcription of secreted Wnt (show WNT2 Proteins) antagonists.
Substantial evidence is found for a dual origin of olfactory bulb neurons, based on Lhx5 expression in the forebrain during larval development and in the adult.
These results reveal a complex role for Lhx5 in regulating the development and normal distribution of Cajal-Retzius cells in the developing forebrain.
Lhx1 (show LHX1 Proteins) and Lhx5 function together with Pax2 (show PAX2 Proteins), Pax5 (show PAX5 Proteins) and Pax8 (show PAX8 Proteins) to establish a GABAergic inhibitory-neurotransmitter program in dorsal horn interneurons.
Lhx1 (show LHX1 Proteins) and Lhx5, and their cofactor Ldb1 (show LDB1 Proteins), control Purkinje cell differentiation in the developing cerebellum.
The second wave of expression at E12.5 includes Lhx3 (show LHX3 Proteins), 5, 9, Isl2 (show ISL2 Proteins), and Lmx1b (show LMX1B Proteins) in the differentiating sensory epithelia with cellular specificities.
Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
, LIM homeobox 5
, LIM homeobox protein 5
, LIM/homeobox protein Lhx5-like
, LIM/homeobox protein Lhx5
, homeobox protein LIM-5
, LIM class homeodomain protein
, homeobox protein LIM-2
, LIM homeo box protein 5