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LHX6 encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. Additionally we are shipping LIM Homeobox 6 Kits (20) and LIM Homeobox 6 Proteins (3) and many more products for this protein.
Showing 10 out of 74 products:
Human Monoclonal LHX6 Primary Antibody for WB - ABIN393942
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Show all 5 references for ABIN393942
Human Polyclonal LHX6 Primary Antibody for EIA, WB - ABIN953168
Estécio, Youssef, Rahal, Fukuyama, Góis-Filho, Maniglia, Goloni-Bertollo, Issa, Tajara: LHX6 is a sensitive methylation marker in head and neck carcinomas. in Oncogene 2006
Show all 4 references for ABIN953168
Human Polyclonal LHX6 Primary Antibody for EIA, IHC (p) - ABIN356903
Jepsen, Solum, Zhou, McEvilly, Kim, Glass, Hermanson, Rosenfeld: SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. in Nature 2007
Show all 3 references for ABIN356903
Human Polyclonal LHX6 Primary Antibody for IHC (p) - ABIN388187
López-Bendito, Sánchez-Alcañiz, Pla, Borrell, Picó, Valdeolmillos, Marín: Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
Show all 3 references for ABIN388187
Cow (Bovine) Polyclonal LHX6 Primary Antibody for IHC, WB - ABIN2779717
Kimura, Ueno, Nakashima, Taga: A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains. in Journal of biochemistry 1999
LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.
LHX6 is a putative tumour suppressor gene with epigenetic silencing in lung cancer.
LHX6 is a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2 (show PITX2 Antibodies)) to regulate odontogenesis
found positive association of LHX6 with Tourette syndrome in some European populations, not others. LHX6 demonstrates a high degree of population differentiation and is correlated with the North to South axis of European genetic variation.
Hypermethylation of LHX6 is associated with cervical cancer.
differentially methylated hypermethylation of LHX6 is a good cancer marker in HNSCC as well as in other kinds of neoplasias and confirm the importance of searching for markers of epigenetic dysregulation in cancer
Lhx6 and Lhx8 (show LHX8 Antibodies) promote palate development through negative regulation of a cell cycle inhibitor (show CDKN2A Antibodies) gene, p57Kip2 (show CDKN1C Antibodies)
Studies indicate that LIM (show PDLIM5 Antibodies) homeobox (show PRRX1 Antibodies) proteins Lhx6 and -8 mRNAs are primarily expressed in the ventral telencephalon, specifically in the medial ganglionic eminence (MGE) of the basal forebrain and in subsets of neurons in the striatum.
The data of this study showed the molecular identity of Lhx6 mutants and introduce technologies to test mechanisms in GABAergic interneuron differentiation.
Lhx6 plays an important role in the maturation of cortical interneurons and the formation of inhibitory circuits in the mammalian cortex
Msx1 (show MSX1 Antibodies) interacts with Lhx6 and Sna (show SNAI1 Antibodies) in vivo. A network of transcription factors operates during early tooth morphogenesis.
Lhx6 and Lhx8 (show LHX8 Antibodies) coordinately induce neuronal expression of Shh (show SHH Antibodies) that controls the generation of interneuron progenitors.
Lhx6 functions may be partially redundant in the mesenchyme of the secondary palate, but not in the palatal epithelium.
Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus.
This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
LIM homeobox protein 6
, LIM homeobox 6
, LIM homeodomain transcription factor, N terminal-like
, putative LIM homeodomain transcription factor, N terminal
, LIM homeodomain protein
, LIM/homeobox protein Lhx6-like
, LIM homeodomain protein 6.1
, LIM/homeobox protein Lhx6
, LIM/homeobox protein Lhx6.1
, LIM-homeodomain protein 6.1