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LIM and SH3 Protein 1 Proteins (LASP1)

LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. Additionally we are shipping LASP1 Antibodies (102) and LASP1 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LASP1 3927 Q14847
LASP1 16796 Q61792
LASP1 29278 Q99MZ8
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Top LASP1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,673.00
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,674.83
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,682.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,682.17
Details

LASP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced LASP1 Proteins

  1. Human LASP1 Protein expressed in Escherichia coli (E. coli) - ABIN1047340 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 5 references for ABIN1047340

  2. Human LASP1 Protein expressed in Escherichia coli (E. coli) - ABIN667659 : Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: Lysine acetylation targets protein complexes and co-regulates major cellular functions. in Science (New York, N.Y.) 2009 (PubMed)
    Show all 2 references for ABIN667659

More Proteins for LIM and SH3 Protein 1 (LASP1) Interaction Partners

Human LIM and SH3 Protein 1 (LASP1) interaction partners

  1. LASP-1 associated with UHRF1 (show UHRF1 Proteins), G9a (show EHMT2 Proteins), Snail1 (show SNAI1 Proteins) and di- and tri (show VANGL2 Proteins)-methylated histoneH3 in a CXCL12 (show CXCL12 Proteins)-dependent manner based on immunoprecipitation and proximity ligation assays

  2. LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P (show S100P Proteins) via the PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway.

  3. LASP-1, mediated by miR (show MLXIP Proteins)-203, has crucial functions in the proliferation, migration and invasion of human non-small cell lung cancer

  4. Detecting an affection of migratory processes after LASP-1 silencing, we propose that LASP-1 could impact on metastasis of CC [choriocarcinoma]cells.

  5. Results identified LASP1 as a hitherto unknown protein in melanocytes and as novel partner of dynamin (show DNM1 Proteins) in the physiological process of membrane constriction and melanosome vesicle release.

  6. Our results suggest that LASP-1 mRNA overexpression may be mainly implicated in female hepatocellular carcinoma (HCC (show FAM126A Proteins)) and cirrhotic HCCs (show HCCS Proteins); and that LASP1 may play its role with vimentin (show VIM Proteins) in HCC (show FAM126A Proteins) cells.

  7. LASP-1 overexpression was associated with aggressive phenotype in clear cell renal cell cancer.

  8. LASP1 plays key roles in cell structure, physiological processes, and cell signaling; overexpression contributes to cancer aggressiveness [review]

  9. LIM and SH3 protein 1 induces TGFbeta (show TGFB1 Proteins)-mediated epithelial-mesenchymal transition in human colorectal cancer by regulating S100A4 (show S100A4 Proteins) expression.

  10. Study revealed that LASP1 phosphorylation results in an association with CRKL (show CRKL Proteins) - another specific BCR-ABL (show ABL1 Proteins) substrate and bona fide biomarker for BCR-ABL (show ABL1 Proteins) activity.

Mouse (Murine) LIM and SH3 Protein 1 (LASP1) interaction partners

  1. Results defined LASP1 as a direct target gene for HIF1alpha (show HIF1A Proteins) upregulation that is critical for metastatic progression of PDAC.

  2. Data show that MEFs derived from Lasp1(-/-) mice migrated more rapidly in vitro.

  3. LIM-nebulette (show NEBL Proteins), Lasp-1, and zyxin (show ZYX Proteins) may play an important role in the organization of focal adhesions

  4. Lasp-1 is a dynamic focal adhesion protein necessary for cell migration and survival in response to growth factors and ECM (show MMRN1 Proteins) proteins.

  5. Data suggest that there are no functional differences between human and mouse LASP-1.

  6. The role of Lasp1 in the regulation of hydrochloride secretion in vivo was studied in a murine model with a targeted disruption of the Lasp-1 gene.

  7. role of Lasp1 in chondrocyte differentiation during cartilage to bone transition

LASP1 Protein Profile

Protein Summary

This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.

Gene names and symbols associated with LIM and SH3 Protein 1 Proteins (LASP1)

  • LIM and SH3 domain protein 1 (lasp1)
  • LIM and SH3 protein 1 (lasp1)
  • LIM and SH3 protein 1 (LASP1)
  • lasp1 protein (lasp1)
  • LIM and SH3 protein 1 (Lasp1)
  • AA408629 protein
  • Def-4 protein
  • fb92f05 protein
  • lasp-1 protein
  • LASP1 protein
  • MGC53336 protein
  • MGC89667 protein
  • mln50 protein
  • SH3P6 protein
  • Tg(Col1a1-lacZ)1Ngma protein
  • wu:fb92f05 protein
  • zgc:77542 protein

Protein level used designations for LIM and SH3 Protein 1 Proteins (LASP1)

LIM and SH3 domain protein 1 , LIM and SH3 protein 1 , lasp1 protein , metastatic lymph node gene 50 protein , LASP-1 , MLN 50 , Tg(11Col1a1)NG , 40 kDa phosphoprotein , phosphoprotein Lasp-1 , pp40

GENE ID SPECIES
100195513 Salmo salar
380354 Xenopus laevis
454620 Pan troglodytes
493322 Xenopus (Silurana) tropicalis
694950 Macaca mulatta
420002 Gallus gallus
3927 Homo sapiens
16796 Mus musculus
29278 Rattus norvegicus
608624 Canis lupus familiaris
323216 Danio rerio
495167 Xenopus laevis
532851 Bos taurus
100009568 Oryctolagus cuniculus
100173670 Pongo abelii
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