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anti-LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) Antibodies

The protein encoded by LRBA is a member of the WDL-BEACH-WD (WBW) gene family. Additionally we are shipping LRBA Proteins (8) and LRBA Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse LRBA LRBA 80877 Q9ESE1
LRBA 987 P50851
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Top anti-LRBA Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: LRBA Antibody [NBP1-90765] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: LRBA Antibody [NBP1-90765] - Staining of human cell line U-251MG shows positivity in cytoplasm & golgi apparatus. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: LRBA Antibody [NBP1-90764] - Immunofluorescent staining of human cell line U-251MG shows positivity in nucleus but not nucleoli & golgi apparatus. Immunohistochemistry-Paraffin: LRBA Antibody [NBP1-90764] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit FITC ELISA, IHC, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit Biotin ELISA, IHC, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit HRP ELISA, IHC, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 9 to 11 Days
$328.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit Biotin   100 μg Log in to see 9 to 14 Days
$378.13
Details
Human Rabbit FITC   100 μg Log in to see 9 to 14 Days
$378.13
Details
Human Rabbit HRP   100 μg Log in to see 9 to 14 Days
$378.13
Details

LRBA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


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Top referenced anti-LRBA Antibodies

  1. Human Polyclonal LRBA Primary Antibody for ICC, IF - ABIN4331440 : Lopez-Herrera, Tampella, Pan-Hammarström, Herholz, Trujillo-Vargas, Phadwal, Simon, Moutschen, Etzioni, Mory, Srugo, Melamed, Hultenby, Liu, Baronio, Vitali, Philippet, Dideberg, Aghamohammadi et al.: Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity. ... in American journal of human genetics 2012 (PubMed)

  2. Human Polyclonal LRBA Primary Antibody for ICC, IF - ABIN4331442 : Burns, Zenner, Plagnol, Curtis, Mok, Eisenhut, Kumararatne, Doffinger, Thrasher, Nejentsev: LRBA gene deletion in a patient presenting with autoimmunity without hypogammaglobulinemia. in The Journal of allergy and clinical immunology 2012 (PubMed)

More Antibodies against LRBA Interaction Partners

Human LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) interaction partners

  1. Among 2 brothers homozygous for LPS responsive beige-like anchor protein (show CELSR3 Antibodies) (LRBA) mutation, one developed Evans syndrome and deceased at age 8.5, and his brother carried the same homozygous LRBA mutation with early-onset erosive polyarthritis.

  2. diagnosis of LRBA deficiency was confirmed by a fluorescence-activated cell sorting-based immunoassay

  3. Variants of LRBA were associated with common variable immunodeficiency.

  4. A homozygous missense mutation in lipopolysaccharide-responsive and beige (show LYST Antibodies)-like anchor gene is associated with inflammatory bowel disease.

  5. LRBA mutation was associated with an autoimmune lymphoproliferative syndrome-like disease characterized by splenomegaly and lymphadenopathy, cytopenia, elevated double negative T cells and raised serum Fas ligand (show FASL Antibodies) levels.

  6. Patients with LRBA deficiency manifested a dramatic and sustained improvement in response to abatacept, a CTLA4 (cytotoxic T lymphocyte antigen-4 (show CTLA4 Antibodies))-immunoglobulin fusion drug.

  7. LRBA deficiency is a novel cause of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX (show FOXP3 Antibodies)) syndrome and Treg cell deficiency associated with metabolic dysfunction and increased apoptosis of Treg cells.

  8. A truncating mutation in LRBA, which abolished protein expression, was identified as the most likely candidate in a consanguineous family with chronic inflammatory bowel disease-like disorder and combined immunodeficiency.

  9. mutations in LRBA cause an immune deficiency characterized by defects in B cell activation (show BLNK Antibodies) and autophagy and by susceptibility to apoptosis, associated with a clinical phenotype of hypogammaglobulinemia and autoimmunity

  10. The crystal structure of the aPH (show APEH Antibodies)-BEACH domains of LRBA were studied.

LRBA Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LRBA

  • LPS-responsive beige-like anchor (Lrba) antibody
  • LPS-responsive vesicle trafficking, beach and anchor containing (LRBA) antibody
  • BGL antibody
  • C80285 antibody
  • CDC4L antibody
  • CVID8 antibody
  • D3Ertd775e antibody
  • LAB300 antibody
  • LBA antibody

Protein level used designations for LRBA

beige-like protein , lipopolysaccharide-responsive and beige-like anchor protein , CDC4-like protein , vesicle trafficking, beach and anchor containing

GENE ID SPECIES
80877 Mus musculus
987 Homo sapiens
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