anti-LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) Antibodies

The protein encoded by LRBA is a member of the WDL-BEACH-WD (WBW) gene family. Additionally we are shipping LRBA Proteins (8) and LRBA Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse LRBA LRBA 80877 Q9ESE1
LRBA 987 P50851
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Top anti-LRBA Antibodies at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: LRBA Antibody [NBP1-90764] - Immunofluorescent staining of human cell line U-251MG shows positivity in nucleus but not nucleoli & golgi apparatus. Immunohistochemistry-Paraffin: LRBA Antibody [NBP1-90764] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: LRBA Antibody [NBP1-90765] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: LRBA Antibody [NBP1-90765] - Staining of human cell line U-251MG shows positivity in cytoplasm & golgi apparatus. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Biotin ELISA, IHC, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit HRP ELISA, IHC, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit FITC ELISA, IHC, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 13 to 16 Days
$328.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 7 to 9 Days
$581.17
Details
Human Rabbit Un-conjugated IHC (p)   100 μL Log in to see 11 to 12 Days
$420.00
Details
Human Rabbit FITC   100 μg Log in to see 11 to 16 Days
$371.25
Details
Human Rabbit HRP   100 μg Log in to see 11 to 16 Days
$371.25
Details

LRBA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


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Top referenced anti-LRBA Antibodies

  1. Human Polyclonal LRBA Primary Antibody for ICC, IF - ABIN4331440 : Lopez-Herrera, Tampella, Pan-Hammarström, Herholz, Trujillo-Vargas, Phadwal, Simon, Moutschen, Etzioni, Mory, Srugo, Melamed, Hultenby, Liu, Baronio, Vitali, Philippet, Dideberg, Aghamohammadi et al.: Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity. ... in American journal of human genetics 2012 (PubMed)

  2. Human Polyclonal LRBA Primary Antibody for ICC, IF - ABIN4331442 : Burns, Zenner, Plagnol, Curtis, Mok, Eisenhut, Kumararatne, Doffinger, Thrasher, Nejentsev: LRBA gene deletion in a patient presenting with autoimmunity without hypogammaglobulinemia. in The Journal of allergy and clinical immunology 2012 (PubMed)

More Antibodies against LRBA Interaction Partners

Human LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) interaction partners

  1. As diabetes was the presenting feature in six of nine individuals, we recommend that testing for LRBA mutations is considered in all patients with newly diagnosed neonatal diabetes and in those with infancy-onset diabetes (<12 months), especially when a recessive inheritance is suspected or additional autoimmune features are present

  2. Assessing total CTLA-4 (show CTLA4 Antibodies) expression levels was found to be optimal when restricting analysis to the CD45RA(-)Foxp3 (show FOXP3 Antibodies)(+) fraction. CTLA-4 (show CTLA4 Antibodies) induction following stimulation, and the use of lysosomal-blocking compounds, distinguished CTLA-4 (show CTLA4 Antibodies) from LRBA mutations

  3. Case Report: potential causative role of LRBA gene mutations in juvenile arthritis.

  4. Among 2 brothers homozygous for LPS responsive beige-like anchor protein (show CELSR3 Antibodies) (LRBA) mutation, one developed Evans syndrome and deceased at age 8.5, and his brother carried the same homozygous LRBA mutation with early-onset erosive polyarthritis.

  5. diagnosis of LRBA deficiency was confirmed by a fluorescence-activated cell sorting-based immunoassay

  6. Variants of LRBA were associated with common variable immunodeficiency.

  7. A homozygous missense mutation in lipopolysaccharide-responsive and beige (show LYST Antibodies)-like anchor gene is associated with inflammatory bowel disease.

  8. LRBA mutation was associated with an autoimmune lymphoproliferative syndrome-like disease characterized by splenomegaly and lymphadenopathy, cytopenia, elevated double negative T cells and raised serum Fas ligand (show FASL Antibodies) levels.

  9. Patients with LRBA deficiency manifested a dramatic and sustained improvement in response to abatacept, a CTLA4 (cytotoxic T lymphocyte antigen-4 (show CTLA4 Antibodies))-immunoglobulin fusion drug.

  10. LRBA deficiency is a novel cause of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX (show FOXP3 Antibodies)) syndrome and Treg cell deficiency associated with metabolic dysfunction and increased apoptosis of Treg cells.

LRBA Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LRBA

  • LPS-responsive beige-like anchor (Lrba) antibody
  • LPS-responsive vesicle trafficking, beach and anchor containing (LRBA) antibody
  • BGL antibody
  • C80285 antibody
  • CDC4L antibody
  • CVID8 antibody
  • D3Ertd775e antibody
  • LAB300 antibody
  • LBA antibody

Protein level used designations for LRBA

beige-like protein , lipopolysaccharide-responsive and beige-like anchor protein , CDC4-like protein , vesicle trafficking, beach and anchor containing

GENE ID SPECIES
80877 Mus musculus
987 Homo sapiens
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