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May promote cell proliferation and inhibition of apoptosis of preadipocytes.. Additionally we are shipping LYRM1 Kits (18) and LYRM1 Antibodies (14) and many more products for this protein.
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Data suggest that the apoptosis regulatory protein LYRM1 gene can be used for marker-assisted selection to improve body measurement and meat quality traits in the Qinchuan cattle population.
The LYRM1 gene may have potential effects on body measurement and meat quality traits in Qinchuan cattle.
alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin (show INS Proteins) resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 (show IRS1 Proteins) and Akt (show AKT1 Proteins).
overexpression of LYRM1 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of LYRM1-induced insulin (show INS Proteins) resistance
Data suggest that LYRM1 might have the potential to modulate cell growth, apoptosis, and heart development.
By increasing cell proliferation and lowering the rate of apoptosis, LYRM1 has the potential to modulate the size of the preadipocyte pool and influence adipose tissue homeostasis
knockdown of LYRM1 induced mitochondrial impairment in P19 (show CDKN2D Proteins) cells during differentiation, which was reflected by decreased ATP synthesis, lower MMP and increased ROS (show ROS1 Proteins) levels.
FCCP-induced mitochondrial dysfunction and insulin (show INS Proteins) resistance are ameliorated by knockdown of LYRM1
Knockdown of the Lyrm1 gene in adipocytes resulted in dramatically increased cellular ATP production, mitochondrial membrane potentials and levels Ucp2 (show UCP2 Proteins) mRNA, while ROS (show ROS1 Proteins) levels were significantly decreased.
results suggest that the expression of LYRM1 mRNA is affected by a variety of factors that are related to insulin (show INS Proteins) sensitivity; LYRM1 may be an important mediator in the development of obesity-related insulin (show INS Proteins) resistance
May promote cell proliferation and inhibition of apoptosis of preadipocytes.
LYR motif containing 1
, LYR motif-containing protein 1