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La Ribonucleoprotein Domain Family, Member 6 Proteins (LARP6)

Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Additionally we are shipping LARP6 Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LARP6 55323 Q9BRS8
LARP6 67557 Q8BN59
Rat LARP6 LARP6 315731  
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Top LARP6 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LARP6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for La Ribonucleoprotein Domain Family, Member 6 (LARP6) Interaction Partners

Human La Ribonucleoprotein Domain Family, Member 6 (LARP6) interaction partners

  1. We postulate that collagen mRNAs directly partition to the endoplasmic reticulum membrane prior to synthesis of the signal peptide and that LARP6 and nonmuscle myosin filaments mediate this process.

  2. Data indicate that LA motif protein LARP6 binding to spliced leader RNA (5'SL) of collagen alpha2(I) mRNA is more stable than the binding to 5'SL of alpha1(I) mRNA.

  3. The study presents the structure of the La motif and RRM1 (show RRM1 Proteins) of human LARP6 uncovering in both cases considerable structural variation in comparison to the equivalent domains in La and revealing an unprecedented fold for the RRM1 (show RRM1 Proteins).

  4. LARP6 is a critical mediator by which IGF-1 (show IGF1 Proteins) augments synthesis of collagen type I in vascular smooth muscle

  5. The results demonstrate that the La modules of the human LARP6 is also active in tRNA-mediated suppression, even in the absence of stable UUU-3'OH trailer protection.

  6. Acheron regulates vascular endothelial proliferation and angiogenesis together with Id1 (show ID1 Proteins) during wound healing.

  7. Achn enhances human breast tumor growth and vascularization and that this activity is dependent on nuclear localization.

  8. LARP6 has a distinctive bipartite RNA binding domain not found in other members of the La superfamily. LARP6 interacts with the two single-stranded regions of the 5' stem-loop.

  9. Acheron may influence differentiation in part via its control of cell adhesion dynamics.

  10. These data define Achn as a newly discovered regulatory molecule that presumably mediates a variety of developmental and homeostatic processes in animals.

Mouse (Murine) La Ribonucleoprotein Domain Family, Member 6 (LARP6) interaction partners

  1. LARP6 is a critical mediator by which IGF-1 (show IGF1 Proteins) augments synthesis of collagen type I in vascular smooth muscle

  2. Acheron regulates vascular endothelial proliferation and angiogenesis together with Id1 (show ID1 Proteins) during wound healing.

  3. Achn enhances human breast tumor growth and vascularization and that this activity is dependent on nuclear localization.

  4. These data define Achn as a newly discovered regulatory molecule that presumably mediates a variety of developmental and homeostatic processes in animals.

  5. achn plays key roles in the processes of differentiation and self-renewal

LARP6 Protein Profile

Protein Summary

Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9 (By similarity).

Gene names and symbols associated with LARP6

  • zgc:162969 (zgc:162969)
  • La ribonucleoprotein domain family, member 6 (LOC100231193)
  • La ribonucleoprotein domain family, member 6 (LARP6)
  • La ribonucleoprotein domain family, member 6 (Larp6)
  • 5430431G03Rik protein
  • Achn protein
  • AI552438 protein
  • im:7142825 protein
  • RGD1308414 protein
  • wu:fa55b04 protein

Protein level used designations for LARP6

La ribonucleoprotein domain family, member 6 , acheron , death-associated LA motif protein , la-related protein 6

GENE ID SPECIES
565767 Danio rerio
100231193 Taeniopygia guttata
55323 Homo sapiens
787569 Bos taurus
67557 Mus musculus
315731 Rattus norvegicus
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