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The protein encoded by LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. Additionally we are shipping Lactate Dehydrogenase A Proteins (56) and Lactate Dehydrogenase A Kits (21) and many more products for this protein.
Showing 10 out of 241 products:
Human Polyclonal Lactate Dehydrogenase A Primary Antibody for EIA, FACS - ABIN953153
Zhuang, Scolyer, Murali, McCarthy, Zhang, Thompson, Hersey: Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010
Show all 6 references for ABIN953153
Rabbit Polyclonal Lactate Dehydrogenase A Primary Antibody for EIA, IF - ABIN116756
Marshall, Goldman: Subpallial dlx2-expressing cells give rise to astrocytes and oligodendrocytes in the cerebral cortex and white matter. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Show all 3 references for ABIN116756
Human Monoclonal Lactate Dehydrogenase A Primary Antibody for EIA, IF - ABIN492378
Le, Cooper, Gouw, Dinavahi, Maitra, Deck, Royer, Vander Jagt, Semenza, Dang: Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 3 references for ABIN492378
Human Polyclonal Lactate Dehydrogenase A Primary Antibody for IF, IHC (p) - ABIN657465
Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010
Show all 2 references for ABIN657465
Human Polyclonal Lactate Dehydrogenase A Primary Antibody for WB - ABIN2785876
Listerman, Bledau, Grishina, Neugebauer: Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. in PLoS genetics 2008
Human Polyclonal Lactate Dehydrogenase A Primary Antibody for FACS, IHC (p) - ABIN653476
Zhao, Zhou, Liu, Ding, Khong, Yu, Fodstad, Tan: Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. in Oncogene 2009
Molecular characterization and expression pattern of the equine lactate dehydrogenase A genes
Dynamic changes of LDH and HBDH activities may be useful in diagnosis of non-thermal low voltage electrical injury and in estimation of post injury intervals.
The number of in advanced-stage diffuse large B cell lymphoma patients with elevated serum lactate dehydrogenase who achieved complete response (CR) after R-CHOP in the non autologous hematopoietic stem cell transplantation (ASCT) group was higher than that in the ASCT group.
this study shows that elevated serum LDH levels are associated with unfavorable prognosis in nasopharyngeal carcinoma patients treated with intensity-modulated radiotherapy
LDHA is a direct target of miR (show MLXIP Antibodies)-34a in regulating glucose metabolism and tumor growth in breast cancer.
IDO (show IDO1 Antibodies), through GCN2 (show EIF2AK4 Antibodies) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc (show MYC Antibodies), resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA and GLS2 (show GLS2 Antibodies)
Findings provide evidence of the cellular functions of lactate dehydrogenase A in the progression of glioblastoma and suggest that lactate dehydrogenase A might act as a potential therapeutic target for glioblastoma treatment.
Reanalysis of genome-wide association study and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism.
LDH and complex I play distinct roles in regulating glycolysis and cell proliferation. Inhibition of these two augments synthetic lethality in melanoma.
Multivariable analysis showed that combined expression of pyruvate kinase type M2 and lactate dehydrogenase A was an independent poor prognostic marker for survival.
Although lactate dehydrogenase A (LDHA) expression varies biphasically during melanoma brain metastasis formation, tumor progression and survival seem to be functionally independent of LDHA.
positive relationship between LDH-A expression and CSC/EMT (show ITK Antibodies) markers was confirmed both in invasive bladder cell line and in 136 MIBC specimens.
Findings suggest that RANKL protein-induced lactate dehydrogenase (LDH) activation stimulates glycolytic and mitochondrial respiratory metabolism via transcription factor NFATc1 signaling.
We propose a profibrotic feed forward loop, in which radiation induces LDHA expression and lactate production, which can lead to further activation of TGF-beta (show TGFB1 Antibodies) to drive the fibrotic process.
High LDH-A expression is associated with metastases in breast tumors.
PGC-1alpha (show PPARGC1A Antibodies) reduces the expression of LDH A and one of its regulators, the transcription factor myelocytomatosis oncogene (show MYC Antibodies).
Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer.
Down-regulation of expression of stress-activated genes PKC-alpha (show PKCa Antibodies), c-Myc (show MYC Antibodies) and LDH-A by alpha-tocopherol in cancerous mice.
The cumulus cells and oocytes showed intense signals for lactate dehydrogenase (LDH)-A respectively.
isoproterenol induces changes in gastrocnemius muscle and serum lactate dehydrogenase expression in mice
Cocaine could inhibit the activities of ATPase (show DNAH8 Antibodies), LDH and SDH (show SDS Antibodies) in cultured splenocytes.
The NADH-cofactor binding site of pig heart LDH is involved in the interaction with acidic phospholipids, in the pig skeletal muscle LDH, neither the cofactor binding site nor the subunit interfacing areas seem to be involved in the interaction.
Both LDHA and COPB1 (show COPB1 Antibodies) were highly expressed in porcine skeletal muscle tissues, implying their potential regulatory function of muscle development.
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
lactate dehydrogenase A1
, L-lactate dehydrogenase A chain
, LDH muscle subunit
, lactate dehydrogenase C
, lactate dehydrogenase-A
, L-lactic acid dehydrogenase
, lactate dehydrogenase A
, M(A)-type lactate dehydrogenase
, lactate dehydrogenase-M
, cell proliferation-inducing gene 19 protein
, lactate dehydrogenase M
, proliferation-inducing gene 19
, renal carcinoma antigen NY-REN-59
, lactate dehydrogenase 1, A chain
, lactate dehydrogenase A4
, lactate dehydrogenase A-like