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anti-Lactate Dehydrogenase A (LDHA) Antibodies

The protein encoded by LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. Additionally we are shipping Lactate Dehydrogenase A Proteins (54) and Lactate Dehydrogenase A Kits (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LDHA 3939 P00338
LDHA 16828 P06151
LDHA 24533 P04642
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Top anti-Lactate Dehydrogenase A Antibodies at antibodies-online.com

Showing 10 out of 234 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LDHA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-LDHA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB LDHA Antibody (C-term) (ABIN657465) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the LDHA antibody detected the LDHA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB LDHA Antibody (Center) (ABIN653476) western blot analysis in Ramos,A375 cell line lysates (35 µg/lane).This demonstrates the LDHA antibody detected the LDHA protein (arrow). Formalin-fixed and paraffin-embedded human skin tissue reacted with LDHA Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometry analysis of Hela cells using LDHA Antibody (Center) Cat.-No AP52459PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human skin tissue reacted with LDHA Antibody (Center) Cat.-No AP52459PU-N which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IF, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Rabbit Goat Un-conjugated EIA, IF, IP, WB Figure 1. Western blot analysis shows anti-Lactate Dehydrogenase antibody detects LDH in HeLa cell extracts. Reactivity with LDH is observed in the cytoplasmic fraction (CF) and little to no reactivity in the nuclear fraction (NF). ~30 µg was loaded per lane onto a 10% gel for SDS-PAGE. Comparison to a molecular weight marker (not shown) indicates a single band of ~36 kDa corresponding to the expected molecular weight for the protein. The blot was incubated with a 1:1,000 dilution of the antibody in 5% milk in TBST at room temperature followed by detection using standard procedures. 2 mL Log in to see 6 to 8 Days
$1,435.50
Details
Human Rabbit Un-conjugated FACS, IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Human Mouse Un-conjugated IHC (p) 50 μL Log in to see 6 to 8 Days
$500.50
Details

LDHA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Lactate Dehydrogenase A Antibodies

  1. Human Polyclonal Lactate Dehydrogenase A Primary Antibody for EIA, FACS - ABIN953153 : Zhuang, Scolyer, Murali, McCarthy, Zhang, Thompson, Hersey: Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 (PubMed)
    Show all 6 references for ABIN953153

  2. Rabbit Polyclonal Lactate Dehydrogenase A Primary Antibody for EIA, IF - ABIN116756 : Marshall, Goldman: Subpallial dlx2-expressing cells give rise to astrocytes and oligodendrocytes in the cerebral cortex and white matter. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 (PubMed)
    Show all 3 references for ABIN116756

  3. Human Monoclonal Lactate Dehydrogenase A Primary Antibody for EIA, IF - ABIN492378 : Le, Cooper, Gouw, Dinavahi, Maitra, Deck, Royer, Vander Jagt, Semenza, Dang: Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN492378

  4. Human Polyclonal Lactate Dehydrogenase A Primary Antibody for IF, IHC (p) - ABIN657465 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 2 references for ABIN657465

  5. Human Polyclonal Lactate Dehydrogenase A Primary Antibody for WB - ABIN2785876 : Listerman, Bledau, Grishina, Neugebauer: Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. in PLoS genetics 2008 (PubMed)

  6. Human Polyclonal Lactate Dehydrogenase A Primary Antibody for FACS, IHC (p) - ABIN653476 : Zhao, Zhou, Liu, Ding, Khong, Yu, Fodstad, Tan: Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. in Oncogene 2009 (PubMed)

More Antibodies against Lactate Dehydrogenase A Interaction Partners

Horse (Equine) Lactate Dehydrogenase A (LDHA) interaction partners

  1. Molecular characterization and expression pattern of the equine lactate dehydrogenase A genes

Rabbit Lactate Dehydrogenase A (LDHA) interaction partners

  1. Dynamic changes of LDH and HBDH activities may be useful in diagnosis of non-thermal low voltage electrical injury and in estimation of post injury intervals.

Human Lactate Dehydrogenase A (LDHA) interaction partners

  1. IDO (show IDO1 Antibodies), through GCN2 (show EIF2AK4 Antibodies) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc (show MYC Antibodies), resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA and GLS2 (show GLS2 Antibodies)

  2. Findings provide evidence of the cellular functions of lactate dehydrogenase A in the progression of glioblastoma and suggest that lactate dehydrogenase A might act as a potential therapeutic target for glioblastoma treatment.

  3. Reanalysis of genome-wide association study and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism.

  4. LDH and complex I play distinct roles in regulating glycolysis and cell proliferation. Inhibition of these two augments synthetic lethality in melanoma.

  5. Multivariable analysis showed that combined expression of pyruvate kinase type M2 and lactate dehydrogenase A was an independent poor prognostic marker for survival.

  6. Although lactate dehydrogenase A (LDHA) expression varies biphasically during melanoma brain metastasis formation, tumor progression and survival seem to be functionally independent of LDHA.

  7. positive relationship between LDH-A expression and CSC/EMT (show ITK Antibodies) markers was confirmed both in invasive bladder cell line and in 136 MIBC specimens.

  8. FOXM1 (show FOXM1 Antibodies)-LDHA signaling functioned as a stimulator of glycolysis and promoted gastric cancer progression.

  9. Mammalian photoreceptors contain dimeric and tetrameric PKM2 and LDH-A. This is consistent with the ability to switch between energy production and biosynthesis like a proliferating tissue, possibly due to demands of opsin (show RHO Antibodies) synthesis.

  10. We propose a profibrotic feed forward loop, in which radiation induces LDHA expression and lactate production, which can lead to further activation of TGF-beta (show TGFB1 Antibodies) to drive the fibrotic process.

Mouse (Murine) Lactate Dehydrogenase A (LDHA) interaction partners

  1. Findings suggest that RANKL protein-induced lactate dehydrogenase (LDH) activation stimulates glycolytic and mitochondrial respiratory metabolism via transcription factor NFATc1 signaling.

  2. We propose a profibrotic feed forward loop, in which radiation induces LDHA expression and lactate production, which can lead to further activation of TGF-beta (show TGFB1 Antibodies) to drive the fibrotic process.

  3. High LDH-A expression is associated with metastases in breast tumors.

  4. PGC-1alpha (show PPARGC1A Antibodies) reduces the expression of LDH A and one of its regulators, the transcription factor myelocytomatosis oncogene (show MYC Antibodies).

  5. Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer.

  6. Down-regulation of expression of stress-activated genes PKC-alpha (show PKCa Antibodies), c-Myc (show MYC Antibodies) and LDH-A by alpha-tocopherol in cancerous mice.

  7. The cumulus cells and oocytes showed intense signals for lactate dehydrogenase (LDH)-A respectively.

  8. isoproterenol induces changes in gastrocnemius muscle and serum lactate dehydrogenase expression in mice

  9. Cocaine could inhibit the activities of ATPase (show DNAH8 Antibodies), LDH and SDH (show SDS Antibodies) in cultured splenocytes.

  10. The increased LDH-A/LDH-B (show LDHB Antibodies) ratio causes high brain lactate levels, which, in turn, are predictive of aging phenotypes.

Pig (Porcine) Lactate Dehydrogenase A (LDHA) interaction partners

  1. The NADH-cofactor binding site of pig heart LDH is involved in the interaction with acidic phospholipids, in the pig skeletal muscle LDH, neither the cofactor binding site nor the subunit interfacing areas seem to be involved in the interaction.

  2. Both LDHA and COPB1 (show COPB1 Antibodies) were highly expressed in porcine skeletal muscle tissues, implying their potential regulatory function of muscle development.

Lactate Dehydrogenase A (LDHA) Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.

Gene names and symbols associated with LDHA

  • lactate dehydrogenase A (ldha) antibody
  • lactate dehydrogenase A (ldha-b) antibody
  • lactate dehydrogenase A (LDHA) antibody
  • lactate dehydrogenase A (Ldha) antibody
  • lactate dehydrogenase A (LOC100357659) antibody
  • lactate dehydrogenase A4 (ldha) antibody
  • lactate dehydrogenase B (ldhb-b) antibody
  • GSD11 antibody
  • l7R2 antibody
  • LDH-A antibody
  • ldh-h antibody
  • LDH-M antibody
  • Ldh1 antibody
  • ldha antibody
  • ldha-B antibody
  • ldha1 antibody
  • ldhab antibody
  • ldhbb antibody
  • LDHC antibody
  • Ldhm antibody
  • pig19 antibody
  • trg-5 antibody

Protein level used designations for LDHA

lactate dehydrogenase A1 , L-lactate dehydrogenase A chain , LDH-A , LDH-M , LDH muscle subunit , lactate dehydrogenase C , lactate dehydrogenase-A , L-lactic acid dehydrogenase , lactate dehydrogenase A , upsilon-crystallin , M(A)-type lactate dehydrogenase , lactate dehydrogenase-M , cell proliferation-inducing gene 19 protein , lactate dehydrogenase M , proliferation-inducing gene 19 , renal carcinoma antigen NY-REN-59 , M-LDH , lactate dehydrogenase 1, A chain , lactate dehydrogenase A4 , lactate dehydrogenase A-like , ldha1

GENE ID SPECIES
394758 Xenopus (Silurana) tropicalis
398121 Xenopus laevis
451063 Pan troglodytes
476882 Canis lupus familiaris
503513 Monodelphis domestica
784938 Bos taurus
791112 Ornithorhynchus anatinus
100057016 Equus caballus
100009107 Oryctolagus cuniculus
3939 Homo sapiens
100713875 Cavia porcellus
16828 Mus musculus
24533 Rattus norvegicus
407245 Sus scrofa
281274 Bos taurus
396221 Gallus gallus
100357659 Oryctolagus cuniculus
100173786 Pongo abelii
30496 Danio rerio
394355 Xenopus laevis
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