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anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Antibodies

LGALS8 encodes a member of the galectin family. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 8 Kits (49) and Lectin, Galactoside-Binding, Soluble, 8 Proteins (31) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LGALS8 56048 Q9JL15
LGALS8 3964 O00214
LGALS8 116641  
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Top anti-Lectin, Galactoside-Binding, Soluble, 8 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-LGALS8 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using LEG8 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using LEG8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged LGALS8 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: LGALS8 transfected 293T lysates 10% SDS PAGE antibody diluted at 1:5000 100 μL Log in to see 2 to 3 Days
$292.60
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-LGALS8 / Galectin-8 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959345 concentration 5 ug/ml. Anti-LGALS8 / Galectin-8 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959345 concentration 5 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Galectin 8 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Galectin 8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB LGALS8 Antibody (C-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the LGALS8 antibody detected the LGALS8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemistry (IHC) analyzes of Galectin-8 antibody in paraffin-embedded human prostate carcinoma tissue. Western blot (WB) analysis of Galectin-8 antibody in extracts from 3T3 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

LGALS8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Lectin, Galactoside-Binding, Soluble, 8 Antibodies

  1. Human Monoclonal LGALS8 Primary Antibody for ELISA, WB - ABIN394563 : Cludts, Decaestecker, Mahillon, Chevalier, Kaltner, André, Remmelink, Leroy, Gabius, Saussez: Galectin-8 up-regulation during hypopharyngeal and laryngeal tumor progression and comparison with galectin-1, -3 and -7. in Anticancer research 2010 (PubMed)
    Show all 5 references for ABIN394563

  2. Chicken Polyclonal LGALS8 Primary Antibody for WB - ABIN2785503 : Yamamoto, Nishi, Shoji, Itoh, Lu, Hirashima, Nakamura: Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T-cells. in Journal of biochemistry 2008 (PubMed)

  3. Human Polyclonal LGALS8 Primary Antibody for IHC, ELISA - ABIN1534464 : Gopalkrishnan, Roberts, Tuli, Kang, Christiansen, Fisher: Molecular characterization of prostate carcinoma tumor antigen-1, PCTA-1, a human galectin-8 related gene. in Oncogene 2000 (PubMed)

More Antibodies against Lectin, Galactoside-Binding, Soluble, 8 Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) interaction partners

  1. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (show VEGFC Antibodies), podoplanin (show PDPN Antibodies) and integrin pathways plays a key role.

  2. Gal (show GAL Antibodies)-8mut was unable to induce T-cell proliferation, but efficiently co-stimulated antigen-specific responses, bothin vitroandin vivo.

  3. Gal-8 emerges as an attractive therapeutic candidate.

  4. Galectin-8 induces RANKL (show TNFSF11 Antibodies) expression, osteoclastogenesis, and bone mass reduction in mice.

  5. Gal-8 stimulated naive T cells, but had an antiproliferative effect when these cells were activated.A dose of recombinant Gal-8 administered with a suboptimal Ag dose to DO11.10 mice strengthened weak responses in vivo.

  6. a novel role for Gal-8 in collaboration with Gal-1 (show LGALS1 Antibodies) in plasma cell formation, and suggest the possibility of using distinct LacNAc ligands to modulate the function of Gals.

  7. The findings of the present study delineate the differential molecular requirements for Gal-8 activities on T-cells, and suggest a dual activity relying on activation state.

  8. downstream effectors of PI3K, including PKB (show AKT2 Antibodies) and p70 S6 kinase (show PRKACB Antibodies), in part mediate cell adhesion, spreading, and microspike formation induced by galectin-8

  9. galectin-8 is expressed in the thymus in mouse, which suggests an active role for this lectin in shaping the mature T cell repertoire

  10. Taken together, our findings support a distinctive role for locally produced Gal-8 as an enhancer of otherwise borderline immune responses and also suggest that Gal-8 might fuel the reactivity at inflammatory foci.

Human Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) interaction partners

  1. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (show VEGFC Antibodies), podoplanin (show PDPN Antibodies) and integrin pathways plays a key role.

  2. Platelet-derived factor V/Va is generated following endocytosis of the plasma-derived molecule by the platelet precursor cells, megakaryocytes, via a two receptor system consisting of LRP-1 (show LRP1 Antibodies) and an unidentified specific "binding site".

  3. Gal-8 expression is a potential independent unfavorable prognostic indicator for postoperative recurrence of patients with localized pT1 (show ZNF77 Antibodies) clear cell renal cell carcinoma (show MOK Antibodies)

  4. The fundamental roles of galectin-8 in human anaplastic large cell lymphoma

  5. The implications of gal-8 in tumor angiogenesis remain to be further explored, but it is exciting to speculate that modulating gal-8-glycan interactions could be used to block lymphatic-vascular connections vital for metastasis

  6. We integrate here the available information on Gal-8 expression in different tumor types and attempt to elucidate associations of its expression and localization with tumor progression[review]

  7. these results not only confirm the pro-inflammatory role we have already proposed for Gal-8 in other cellular systems but also suggest that this lectin is orchestrating the interaction between leukocytes, platelets and endothelial cells

  8. Whereas Galectin (Gal)-1, -3, and -8 triggered vascular endothelial growth factor (VEGF) release, only Gal-8 induced endostatin secretion.

  9. Focusing on the F19Y change in galectin-8, we study of consequences of a single-site substitution in the carbohydrate recognition domain of this family of cellular effectors.

  10. Data indicate that the binding site in galectin-8 is essential for the recruitment of the autophagy receptor NDP52 (show CALCOCO2 Antibodies) to cytosol-exposed Salmonella Typhimurium.

Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Antigen Profile

Protein Summary

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with LGALS8

  • lectin, galactoside-binding, soluble, 8 (LGALS8) antibody
  • lectin, galactose binding, soluble 8 (Lgals8) antibody
  • lectin, galactoside-binding, soluble, 8 (Lgals8) antibody
  • lectin, galactoside-binding, soluble, 8 (galectin 8) (lgals8) antibody
  • 1200015E08Rik antibody
  • AI326142 antibody
  • D13Ertd524e antibody
  • Gal-8 antibody
  • galectin-8 antibody
  • Lgals-8 antibody
  • LGALS8 antibody
  • PCTA-1 antibody
  • PCTA1 antibody
  • Po66-CBP antibody
  • xgalectin-VIIIa antibody

Protein level used designations for LGALS8

lectin, galactoside-binding, soluble, 8 , lectin, galactoside-binding, soluble, 8 (galectin 8) , galectin-8-like , gal-8 , galectin 8 , galectin-8 , galectin-8L , lectin, galactose binding, soluble 5 , galectin-8 variant II , Po66 carbohydrate binding protein , galectin-8g , po66 carbohydrate-binding protein , prostate carcinoma tumor antigen 1 , 30 kDa S-type lectin , RL-30 , lectin, galactose binding, soluble 8 , galectin family xgalectin-VIIIa , xgalectin-VIII

GENE ID SPECIES
710375 Macaca mulatta
743841 Pan troglodytes
100436942 Pongo abelii
100595058 Nomascus leucogenys
56048 Mus musculus
430948 Gallus gallus
3964 Homo sapiens
479193 Canis lupus familiaris
100156193 Sus scrofa
506977 Bos taurus
116641 Rattus norvegicus
100343919 Oryctolagus cuniculus
100733991 Cavia porcellus
101115850 Ovis aries
398442 Xenopus laevis
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