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Lectin, Galactoside-Binding, Soluble, 9 Proteins (LGALS9)

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 9 Antibodies (179) and Lectin, Galactoside-Binding, Soluble, 9 Kits (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LGALS9 16859 O08573
LGALS9 3965 O00182
LGALS9 25476 P97840
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Top Lectin, Galactoside-Binding, Soluble, 9 Proteins at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$103.27
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Mammalian Cells Human DYKDDDDK Tag 100 μg Log in to see 13 to 16 Days
$1,490.50
Details
HOST_Escherichia coli (E. coli) Human HIS-GST 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag   10 μg Log in to see 15 to 19 Days
$314.16
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,964.50
Details

LGALS9 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , ,
, , ,
Rat (Rattus) ,

Top referenced Lectin, Galactoside-Binding, Soluble, 9 Proteins

  1. Human LGALS9 Protein expressed in HEK-293 - ABIN2666753 : Bacigalupo, Manzi, Rabinovich, Troncoso: Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma. in World journal of gastroenterology : WJG 2013 (PubMed)
    Show all 7 references for ABIN2666753

  2. Human LGALS9 Protein expressed in Escherichia coli (E. coli) - ABIN667765 : Türeci, Schmitt, Fadle, Pfreundschuh, Sahin: Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. in The Journal of biological chemistry 1997 (PubMed)
    Show all 2 references for ABIN667765

  3. Mouse (Murine) LGALS9 Protein expressed in Escherichia coli (E. coli) - ABIN1098734 : Hirashima, Kashio, Nishi, Yamauchi, Imaizumi, Kageshita, Saita, Nakamura: Galectin-9 in physiological and pathological conditions. in Glycoconjugate journal 2004 (PubMed)
    Show all 2 references for ABIN1098734

  4. Human LGALS9 Protein expressed in Wheat germ - ABIN1309346 : Qi, Song, Shen, Xu, Shen, Luo, Zhong, Wang, Chu, Song: Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice. in Immunology letters 2012 (PubMed)

More Proteins for Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) interaction partners

  1. The Gal-9/Tim-3 (show HAVCR2 Proteins) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  2. These results indicate the possibility that cooperative binding of oligosaccharide and neighboring polypeptide structures of monoclonal IgE to galectin-9 affects the overall affinity and specificity of the IgE-lectin interaction.

  3. galectin-9 functions as a novel alarmin by augmenting the inflammatory response in sepsis development during pulmonary F. novicida infection.

  4. Gal-9 has a role in the maintenance of hepatic homeostasis and preventing liver ischemia-reperfusion injury

  5. Gal-9, a natural TIM-3 (show HAVCR2 Proteins) ligand, was produced primarily by and released from ischemia-reperfusion-stressed hepatocytes, both in vivo and in vitro.

  6. Galectin-9 functions as an astrocyte-microglia communication signal and promotes cytokine production from microglia in a Tim-3 (show HAVCR2 Proteins) independent manner.

  7. galectin-9, in addition to being an effector molecule for regulatory T cells cells, acts synergistically with TGF-beta (show TGFB1 Proteins) to enforce iTreg cell differentiation and maintenance.

  8. Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

  9. action of agonist anti-4-1BB (show TNFRSF9 Proteins) in suppressing autoimmune and allergic inflammation was completely dependent on Galectin-9 (Gal-9). Gal-9 directly bound to 4-1BB (show TNFRSF9 Proteins), in a site distinct from the binding site of antibodies and the natural ligand of 4-1BB (show TNFRSF9 Proteins)

  10. Tim-3 (show HAVCR2 Proteins)/galectin-9 pathway plays a critical role in the homeostasis of hepatic Tregs through the elimination induction in Teffs and the inhibition of IFN-gamma (show IFNG Proteins) release.

Human Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) interaction partners

  1. The Gal-9/Tim-3 (show HAVCR2 Proteins) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  2. Gal-9 suppressed T-helper 17 (Th17) and expanded regulatory T cells (Tregs), resulting in decreased IL-17 (show IL17A Proteins) production and increased secretion of TGF-beta1 (show TGFB1 Proteins)

  3. an abnormal Tim-3 (show HAVCR2 Proteins)/Gal-9 pathway was able to facilitate the development of preeclampsia.

  4. Galectin-9 stimulated migration in human NK-92 cells by affecting F-actin polarization through the Rho/ROCK1 (show ROCK1 Proteins) signaling pathway.

  5. may contribute to elevated galectin-9 and adaptive immune inhibition in hepatitis C virus infection

  6. LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux

  7. TIM-3 (show HAVCR2 Proteins) and its ligand, galectin-9 (Gal-9), constitute an autocrine loop critical for leukemic stem cells self-renewal and development of human acute myeloid leukemia (show BCL11A Proteins).

  8. Galectin-9 is involved in the pathogenesis of autoimmune thyroid disease.Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells.

  9. Study found that LGALS9 was expressed in 68.4% of the human gastrointestinal stromal tumors (GIST) and Tim-3 (show HAVCR2 Proteins) in the infiltrated NK cells of 68.4% of GISTs and suggest that Tim-3 (show HAVCR2 Proteins)/LGALS9 pathway may be involved in the immune checkpoint mechanism of GISTs.

  10. We also observed that the Gal-9/miR (show MLXIP Proteins)-22 axis may influence lymphocyte apoptosis and tumor cell proliferation. These studies contribute to a further understanding of the microRNAmediated regulation of the Gal-9 pathway .

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) interaction partners

  1. The Tim-3 (show HAVCR2 Proteins)/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1 (show LGALS1 Proteins), LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 mRNA would display a differential expression pattern in the endometrium.

Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) Protein Profile

Protein Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with LGALS9

  • lectin, galactoside-binding, soluble, 9 (lgals9)
  • zgc:92326 (zgc:92326)
  • lectin, galactoside-binding, soluble, 9 (LGALS9)
  • galectin-9 (LOC100350347)
  • galectin-9-like (LOC100728329)
  • lectin, galactose binding, soluble 9 (Lgals9)
  • lectin, galactoside-binding, soluble, 9 (Lgals9)
  • AA407335 protein
  • AI194909 protein
  • AI265545 protein
  • ecalectin protein
  • gal-9 protein
  • galectin-9 protein
  • HUAT protein
  • Lgals5 protein
  • LGALS9 protein
  • LGALS9A protein
  • LGALS35 protein
  • UAT protein
  • UATP.I protein
  • wu:fd20c09 protein
  • zgc:111833 protein

Protein level used designations for LGALS9

lectin, galactoside-binding, soluble, 9 , galactoside-binding soluble lectin 9 , galectin 9 , lectin, galactoside-binding, soluble, 9 (galectin 9) , galectin-9 , lectin, galactose binding, soluble 5 , ecalectin , gal-9 , tumor antigen HOM-HD-21 , urate transporter/channel protein , 36 kDa beta-galactoside-binding lectin , Lectin galactose binding soluble 9 (Galectin-9) , Lectin, galactose binding, soluble 9 (Galectin-9) , UAT , urate transporter/channel , urate transporter , urate transporter/channel protein, isoform (UATp,i)

GENE ID SPECIES
733366 Xenopus laevis
100145704 Xenopus (Silurana) tropicalis
327284 Danio rerio
454519 Pan troglodytes
100350347 Oryctolagus cuniculus
100728329 Cavia porcellus
16859 Mus musculus
3965 Homo sapiens
25476 Rattus norvegicus
442861 Canis lupus familiaris
396972 Sus scrofa
510813 Bos taurus
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