You are viewing an incomplete version of our website. Please click to reload the website as full version.

Leucine Zipper, Putative Tumor Suppressor 1 Proteins (LZTS1)

LZTS1 encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. Additionally we are shipping Leucine Zipper, Putative Tumor Suppressor 1 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LZTS1 9638 Q99689
LZTS1 81730 P97577
LZTS1 211134 P60853
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Leucine Zipper, Putative Tumor Suppressor 1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,729.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

LZTS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) Interaction Partners

Human Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) interaction partners

  1. missense variant in the LZTS1 gene was identified in two Ehlers-Danlos syndrome patients in an extended family.

  2. LZTS1 promoter was frequently methylated in IMPC samples.

  3. Compared with the normal hepatocyte cells, LZTS1 expression in hepatocellular carcinoma cells was significantly lower

  4. miR (show MLXIP Proteins)-135b expression inversely correlated with LZTS1 staining intensity and the Cutaneous Squamous Cell Carcinoma grade.

  5. FEZ1 promotes HIV-1 infection in non-neuronal cells via direct binding to the capsid and kinesin-1 to move the virus into the cell nucleus.

  6. Suggest that LZTS1 plays a potential tumor suppressor role in colorectal cancer progression and represents a valuable clinical prognostic marker of this disease.

  7. Lzts1 was significantly downregulated in breast cancer samples and its deregulation was associated with a higher incidence of tumor recurrence, and to a worse overall survival.

  8. miR (show MLXIP Proteins)-214 functions as an onco-miRNA in osteosarcoma, and its oncogenic effects are mediated chiefly through downregulation of LZTS1

  9. SCOC (show SCOC Proteins) forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC (show SCOC Proteins) dimerization and the SCOC (show SCOC Proteins) surface residue R117 are important for this interaction.

  10. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein (show SCOC Proteins)) and kinesins (kinesin heavy chain (show KIF5A Proteins)) are involved in biological transport process.

Mouse (Murine) Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) interaction partners

  1. The results of this study provide a novel Rap2 (show RAP2A Proteins)-specific regulatory mechanism in synaptic maturation involving PSD-Zip70.

  2. Taken together, the spatial and temporal distribution of Lzts1 is consistent with a potential function(s) in cell cycle regulation, axon growth or guidance, and/or migration of neurons.

  3. Lzts1 deficiency was associated with an increased incidence of both spontaneous and carcinogen-induced cancers in mice.

  4. Partial or complete loss of Lzts1 downregulates Cdc25C (show CDC25C Proteins) and inhibits Cdk1 (show CDK1 Proteins) activity during mitosis, leading to premature transition from metaphase to anaphase.

  5. Loss of one or both LZTS1 alleles hampers the normal defenses of urothelial cells against carcinogens, favoring bladder cancer development, which may make FEZ1 (show FEZ1 Proteins) a target for gene therapy.

Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) Protein Profile

Protein Summary

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Gene names and symbols associated with LZTS1

  • leucine zipper, putative tumor suppressor 1 (LZTS1)
  • leucine zipper, putative tumor suppressor 1 (lzts1)
  • fasciculation and elongation protein zeta 1 (zygin I) (FEZ1)
  • fasciculation and elongation protein zeta 1 (zygin I) (Fez1)
  • leucine zipper, putative tumor suppressor 1 (Lzts1)
  • F37 protein
  • FEZ1 protein
  • LZTS1 protein
  • Psdzip70 protein

Protein level used designations for LZTS1

leucine zipper, putative tumor suppressor 1 , leucine zipper putative tumor suppressor 1-like , fasciculation and elongation protein zeta-1 , zygin I , zygin-1 , protein kinase C-binding protein Zeta1 , zygin 1 , F37/Esophageal cancer-related gene-coding leucine-zipper motif , leucine zipper putative tumor suppressor 1 , F37 esophageal cancer-related leucine zipper motif 1 , leucine-zipper protein FEZ1 , PSD-Zip70

GENE ID SPECIES
464034 Pan troglodytes
486136 Canis lupus familiaris
741727 Pan troglodytes
100030407 Monodelphis domestica
100073437 Ornithorhynchus anatinus
100126058 Xenopus (Silurana) tropicalis
100404687 Callithrix jacchus
100484902 Ailuropoda melanoleuca
100549642 Meleagris gallopavo
100552142 Anolis carolinensis
100604452 Nomascus leucogenys
9638 Homo sapiens
81730 Rattus norvegicus
612764 Canis lupus familiaris
511751 Bos taurus
11178 Homo sapiens
539634 Bos taurus
211134 Mus musculus
266711 Rattus norvegicus
431331 Gallus gallus
Selected quality suppliers for Leucine Zipper, Putative Tumor Suppressor 1 Proteins (LZTS1)
Did you look for something else?