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anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) Antibodies

LGI1 is rearranged as a result of translocations in glioblastoma cell lines. Additionally we are shipping Leucine-Rich, Glioma Inactivated 1 Proteins (5) and Leucine-Rich, Glioma Inactivated 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LGI1 56839 Q9JIA1
LGI1 9211 O95970
LGI1 252892 Q8K4Y5
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Top anti-Leucine-Rich, Glioma Inactivated 1 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemical staining of human brain tissue using AP30496PU-N at 2.5 μg/ml. Western blot analysis of LGI1 in HeLa cell lysate with this product at 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LGI1 in mouse brain tissue lysate with this product at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE antibody diluted at 1:5000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti LGI1/ETL1 Polyclonal Antibody, Unconjugated (ABIN720430) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details

LGI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Leucine-Rich, Glioma Inactivated 1 Antibodies

  1. Human Polyclonal LGI1 Primary Antibody for IHC, ELISA - ABIN1002722 : Gu, Gibert, Wirth, Elischer, Bloch, Meyer, Steinlein, Begemann: Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders. in Molecular biology and evolution 2005 (PubMed)
    Show all 3 references for ABIN1002722

  2. Human Polyclonal LGI1 Primary Antibody for EIA, WB - ABIN500152 : Chernova, Somerville, Cowell: A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors. in Oncogene 1999 (PubMed)

More Antibodies against Leucine-Rich, Glioma Inactivated 1 Interaction Partners

Mouse (Murine) Leucine-Rich, Glioma Inactivated 1 (LGI1) interaction partners

  1. LGI1 has a role in regulating cortical development, which is increasingly becoming recognized as one of the causes of idiopathic epilepsy.

  2. LGI1 and ADAM22 (show ADAM22 Antibodies) form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95 (show DLG4 Antibodies)

  3. Review article demonstrating that LGI1 may be an essential player in the development of the brain

  4. Glutamatergic neuron-targeted loss of Lgi1 causes a severe epileptic phenotype; Lgi1 displays an essential role in brain during the whole life.

  5. Lgi1 contains nuclear localization signal that mediates Lgi1 localization to cytoplasm and nucleus in CNS embryonic neurons.

  6. This study demonistrated that LGI1 plays a critical role in both dendritic and axonal pruning, we identify a novel molecular pathway in synapse and circuit remodeling.

  7. Lgi1 may have a role in establishing normal brain architecture and neuronal functions during brain development suggesting that it may be involved in neurogenesis and neuronal plasticity

  8. LGI1(+/-) and LGI1(-/-) mice may provide useful models for lateral temporal lobe epilepsy, and more generally idiopathic focal epilepsy.

  9. Lgi1 null mutant mice exhibit myoclonic seizures and CA1 (show CA1 Antibodies) neuronal hyperexcitability.

  10. in the brain of C57BL/6J adult mice by in situ hybridization. We found that the LGI1 transcript is mainly expressed in the dentate gyrus and CA3 (show CA3 Antibodies) field of the hippocampus.

Human Leucine-Rich, Glioma Inactivated 1 (LGI1) interaction partners

  1. Clinical analysis of a lateral temporal lobe epilepsy cohort from Turkey and genetic contribution of LGI1 to autosomal dominant lateral temporal lobe epilepsy phenotype

  2. Report of three novel LGI1 mutations, a microdeletion of exon 2 and two missense mutations in exon 8, occurring in two autosomal dominant lateral temporal epilepsy families and in one sporadic patient with lateral temporal epilepsy

  3. study found no cryptic imbalances were in LGI1 in partial epilepsy with auditory features (PEAF) patients, suggesting that LGI1 microdeletions are not a frequent cause of PEAF

  4. The Multiplex ligation-dependent probe amplifications analysis did not reveal any pathogenic changes in the LGI1 gene. Chromosomal rearrangements involving the LGI1 gene were not identified in our series of familial or sporadic LTE (show SLC12A4 Antibodies).

  5. A new LGI1 missense mutation is identified in a large Korean family with autosomal dominant lateral temporal lobe epilepsy.

  6. Seven LGI1-affected individuals report auditory aura (show AURKA Antibodies) and one visual aura (show AURKA Antibodies); three families with autosomal dominant epilepsy and auditory features have novel LGI1 mutations.

  7. Downregulation of LGI1 promotes tumor metastasis in esophageal squamous cell carcinoma.

  8. This study expands the phenotypic spectrum associated with Autosomal dominant lateral temporal lobe epilepsy due to LGI1 mutation and underlines the need for more systematic evaluation of Attention-deficit hyperactivity disorder and related symptoms.

  9. The LGI1-ADAM22 (show ADAM22 Antibodies) interaction is neutralized by autoantibodies to epilepsy-related LGI1 in limbic encephalitis.

  10. This study demonistrated that Low penetrance of autosomal dominant lateral temporal epilepsy in Italian families without LGI1 mutations.

Leucine-Rich, Glioma Inactivated 1 (LGI1) Antigen Profile

Protein Summary

This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

Gene names and symbols associated with LGI1

  • leucine-rich, glioma inactivated 1 (LGI1) antibody
  • leucine-rich, glioma inactivated 1 (LOC733906) antibody
  • leucine-rich, glioma inactivated 1 (lgi1) antibody
  • leucine-rich, glioma inactivated 1 (LOC100219007) antibody
  • leucine-rich repeat LGI family, member 1 (Lgi1) antibody
  • leucine-rich, glioma inactivated 1 (Lgi1) antibody
  • ADLTE antibody
  • ADPAEF antibody
  • ADPEAF antibody
  • BB130740 antibody
  • EPITEMPIN antibody
  • EPT antibody
  • ETL1 antibody
  • IB1099 antibody
  • MGC146600 antibody

Protein level used designations for LGI1

leucine-rich glioma-inactivated protein 1 , leucine-rich, glioma inactivated 1 , leucine-rich glioma-inactivated protein 1-like , epitempin-1 , polymorphic marker clone YB07 , leucine-rich repeat LGI family, member 1 , putative leucine-rich glioma inactivated 1

GENE ID SPECIES
423802 Gallus gallus
700520 Macaca mulatta
733906 Xenopus (Silurana) tropicalis
779819 Xenopus (Silurana) tropicalis
100172937 Pongo abelii
100219007 Taeniopygia guttata
100415038 Callithrix jacchus
100597927 Nomascus leucogenys
56839 Mus musculus
9211 Homo sapiens
477777 Canis lupus familiaris
617080 Bos taurus
252892 Rattus norvegicus
450619 Pan troglodytes
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