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Leucine-Rich Repeat and WD Repeat-Containing Protein 1 Proteins (LRWD1)

Associated component of the origin recognition complex (ORC) required to recruit and stabilize the ORC complex to chromatin. Additionally we are shipping Leucine-Rich Repeat and WD Repeat-Containing Protein 1 Antibodies (21) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LRWD1 222229 Q9UFC0
LRWD1 71735 Q8BUI3
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Top Leucine-Rich Repeat and WD Repeat-Containing Protein 1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LRWD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) Interaction Partners

Human Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) interaction partners

  1. Data show that ORCA acts as a scaffold for the establishment of H3K9 KMT (show CAMKMT Proteins) complex.

  2. This is the first study showing that the expression of the testis-enriched LRWD1 gene is regulated by NF-kappaB (show NFKB1 Proteins).

  3. Data (from studies using recombinant proteins) suggest that deletion of leucine rich (LRR) domain significantly down-regulates expression of LRWD1 protein; LRR domain is significantly correlated with stability of LRWD1 protein.

  4. three coding single-nucleotide polymorphisms (SNP1 (show SNRNP70 Proteins)-SNP3) could be detected in Japanese patients with Sertoli cell-only syndrome

  5. Orc2 protects ORCA from ubiquitin-mediated degradation in vivo.

  6. propose that the dynamic association of ORCA with pre-RC components modulates the assembly of its interacting partners on chromatin and facilitates DNA replication initiation

  7. Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 (show HIST3H3 Proteins) and maintains heterochromatin silencing

  8. Results suggest ORCA-mediated association of ORC to chromatin is critical to initiate preRC assembly in G1 and chromatin organization in post-G1 cells.

Mouse (Murine) Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) interaction partners

  1. immunostaining and immunoprecipitation showed colocalization and interaction between lrwd1 and gamma-tubulin (show TUBG1 Proteins) respectively, implicating lrwd1 as a candidate centrosomal protein. These results suggest that lrwd1 may play an important role in spermatogenesis.

  2. Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 (show HIST3H3 Proteins) and maintains heterochromatin silencing

Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) Protein Profile

Protein Summary

Associated component of the origin recognition complex (ORC) required to recruit and stabilize the ORC complex to chromatin. Probably required for the association of ORC on chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells (By similarity).

Gene names and symbols associated with LRWD1

  • leucine-rich repeats and WD repeat domain containing 1 (LRWD1)
  • leucine-rich repeats and WD repeat domain containing 1 (lrwd1)
  • leucine-rich repeats and WD repeat domain containing 1 (Lrwd1)
  • 1200011O22Rik protein
  • AU042569 protein
  • AW548074 protein
  • CENP-33 protein
  • Orca protein
  • si:dkey-261j4.9 protein
  • wu:fb78b03 protein
  • wu:ft31b04 protein

Protein level used designations for LRWD1

leucine-rich repeats and WD repeat domain containing 1 , leucine-rich repeat and WD repeat-containing protein 1 , ORC-associated protein , Origin recognition complex-associated protein , centromere protein 33 , origin recognition complex associated , origin recognition complex-associated protein

GENE ID SPECIES
417511 Gallus gallus
463928 Pan troglodytes
479725 Canis lupus familiaris
100138861 Bos taurus
100145159 Xenopus (Silurana) tropicalis
222229 Homo sapiens
71735 Mus musculus
327124 Danio rerio
444544 Xenopus laevis
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