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The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. Additionally we are shipping LRG1 Antibodies (80) and LRG1 Proteins (26) and many more products for this protein.
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Human LRG1 ELISA Kit for Sandwich ELISA - ABIN415101
Suresh, Saha, Kaur, Kumar, Dubey, Basak, Tanwar, Bhardwaj, Sengupta, Batra, Upadhyay: Differentially expressed urinary biomarkers in children with idiopathic nephrotic syndrome. in Clinical and experimental nephrology 2016
Results suggest that serum LRG-1 is a promising biomarker for pancreatic cancer.
Results provided evidence for LRG1 function as a novel inducer of epithelial-mesenchymal transition and angiogenesis in colorectal cancer, which was at least partially through promotion of HIF-1alpha (show HIF1A ELISA Kits) expression.
Data show that leucine-rich-alpha-2-glycoprotein 1 (LRG1) is markedly up-regulated and serves as an independent factor of poor outcomes in hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)).
Reanalysis of a total of 47 MDS (show PAFAH1B1 ELISA Kits) patients revealed biomarker candidates, with alpha-2-HS-glycoprotein (show AHSG ELISA Kits) and leucine-rich alpha-2-glycoprotein as the most promising candidates.
Two of these proteins were verified in a separate patient cohort: values of CRP (show CRP ELISA Kits) and LRG1 combined gave a highly significant indication of extended survival post one week of radiotherapy treatment.
Findings suggest that LRG1 promotes invasion and migration of glioma cells through TGF-beta (show TGFB1 ELISA Kits) signaling pathway.
Data found LRG1 as a promising candidate marker for detection of epithelial ovarian cancer (EOC) and the combination of LRG1 and CA125 (show MUC16 ELISA Kits) showed improved performance to distinguish EOC including early stage EOC from non-cases compared to CA125 (show MUC16 ELISA Kits).
LGR1 (show FSHR ELISA Kits) is involved in the inhibition of HCC (show FAM126A ELISA Kits) metastasis.
silencing the expression of LRG1 suppresses the growth of glioblastoma U251 cells in vitro and in vivo, suggesting that LRG1 may play a critical role in glioblastoma development, and it may have potential clinical implications in glioblastoma therapy.
Higher LRG1 is a significant predictor for arterial stiffness, endothelial function, and peripheral arterial disease.
Loss of LRG is associated with Lewis lung carcinoma.
Human LRG (hLRG) concentration in the cerebrospinal fluid (CSF (show CSF2 ELISA Kits)) was measured and hLRG expression in post-mortem human cerebral cortex and mouse LRG (mLRG) in the brain were examined.
Mice lacking Lrg1 develop a mild retinal vascular phenotype but exhibit a significant reduction in pathological ocular angiogenesis.
cDNA clones for murine leucine-rich alpha2-glycoprotein were isolated. Expression of LRG during differentiation of 32Dcl3G cells preceded the expression of lactoferrin (show LTF ELISA Kits) and gelatinase but followed myeloperoxidase (show MPO ELISA Kits).
The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002
, leucine-rich alpha-2-glycoprotein 1
, leucine-rich alpha-2-glycoprotein-like
, leucine rich alpha 2 glycoprotein