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anti-Leukotriene A4 Hydrolase (LTA4H) Antibodies

Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Additionally we are shipping Leukotriene A4 Hydrolase Kits (16) and Leukotriene A4 Hydrolase Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LTA4H 4048 P09960
LTA4H 16993 P24527
LTA4H 299732  
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Top anti-Leukotriene A4 Hydrolase Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LTA4H Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of LTA4H Antibody (Center) (ABIN650745) in T47D cell line lysates (35 µg/lane). LTA4H (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lymph tissue reacted with CORO1A Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LTA4H Antibody (Center) in T47D cell line lysates (35ug/lane). LTA4H (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IP, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LTA4H (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LTA4H. Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-LTA4H mouse monoclonal antibody. (ABIN2452494, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Immunohistochemical staining of paraffin-embedded breast tissue using anti-LTA4H mouse monoclonal antibody. (ABIN2452643, Dilution 1:50) Immunohistochemical staining of paraffin-embedded colon tissue using anti-LTA4Hmouse monoclonal antibody. (ABIN2452643, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LTA4H Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: U937 cell lysate WB Suggested Anti-LTA4H  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: U937 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IP, ELISA, WB 100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details

LTA4H Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
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Mouse (Murine) ,


Rat (Rattus)
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Top referenced anti-Leukotriene A4 Hydrolase Antibodies

  1. Mouse (Murine) Polyclonal LTA4H Primary Antibody for IP, ELISA - ABIN2000677 : Mancini, Evans: Cloning and characterization of the human leukotriene A4 hydrolase gene. in European journal of biochemistry / FEBS 1995 (PubMed)
    Show all 4 references for ABIN2000677

  2. Human Polyclonal LTA4H Primary Antibody for EIA, WB - ABIN453734 : Crosslin, Shah, Nelson, Haynes, Connelly, Gadson, Goldschmidt-Clermont, Vance, Rose, Granger, Seo, Gregory, Kraus, Hauser: Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. in Human genetics 2009 (PubMed)
    Show all 4 references for ABIN453734

  3. Human Polyclonal LTA4H Primary Antibody for IF, IHC (p) - ABIN650745 : Huston, Haeggström, Feller: Cold adaptation of enzymes: structural, kinetic and microcalorimetric characterizations of an aminopeptidase from the Arctic psychrophile Colwellia psychrerythraea and of human leukotriene A(4) hydrolase. in Biochimica et biophysica acta 2008 (PubMed)
    Show all 2 references for ABIN650745

  4. Human Polyclonal LTA4H Primary Antibody for WB - ABIN610961 : Beckhelling, Chang, Chevalier, Ford, Houliston: Pre-M phase-promoting factor associates with annulate lamellae in Xenopus oocytes and egg extracts. in Molecular biology of the cell 2003 (PubMed)

  5. Human Monoclonal LTA4H Primary Antibody for IP, IHC - ABIN2452494 : Tian, Jiang, Tamosiuniene, Sung, Qian, Dhillon, Gera, Farkas, Rabinovitch, Zamanian, Inayathullah, Fridlib, Rajadas, Peters-Golden, Voelkel, Nicolls: Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension. in Science translational medicine 2013 (PubMed)

  6. Cow (Bovine) Polyclonal LTA4H Primary Antibody for WB - ABIN2785676 : Bevan, Dichgans, Wiechmann, Gschwendtner, Meitinger, Markus: Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations. in Stroke; a journal of cerebral circulation 2008 (PubMed)

  7. Human Monoclonal LTA4H Primary Antibody for IF, IP - ABIN2452643 : Wells, OReilly, Szul, Sullivan, Handley, Garrett, McNicholas, Roda, Miller, Tal-Singer, Gaggar, Rennard, Jackson, Blalock: An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease. in American journal of respiratory and critical care medicine 2014 (PubMed)

More Antibodies against Leukotriene A4 Hydrolase Interaction Partners

Zebrafish Leukotriene A4 Hydrolase (LTA4H) interaction partners

  1. lta4h mutations confer hypersusceptibility to mycobacterial infection by redirecting eicosanoid substrates to anti-inflammatory lipoxins.

Xenopus laevis Leukotriene A4 Hydrolase (LTA4H) interaction partners

  1. Mutating F375 in xlLTA4H to tyrosine abolishes the formation of the LTB4 (show PTGR1 Antibodies) isomeric product Delta(6)-trans-Delta(8)-cis (show CISH Antibodies)-LTB4 (show PTGR1 Antibodies).

Human Leukotriene A4 Hydrolase (LTA4H) interaction partners

  1. LTA4H promoter region SNP was associated with susceptibility to bacteriologically confirmed bacterial meningitis but did not influence clinical presentation, disease severity or survival following dexamethasone treatment.

  2. Report no association between LTA4H SNPs and atherosclerotic plaque phenotypes.

  3. The best proteinogenic amino acid recognized by LTA4H is arginine.

  4. The results of our study failed to confirm whether the selected variants in LTA4H gene within the LT metabolism pathway contribute to platelet reactivity in a diabetic population treated with ASA (show ARSA Antibodies).

  5. The LTA4H A-9188>G polymorphism has a strong association with severe asthma in children.

  6. Data indicate that 13S,14S-epoxy-docosahexaenoic acid (DHA) inhibits leukotriene B4 (LTB4 (show PTGR1 Antibodies)) biosynthesis by leukotriene A4 hydrolase (LTA4H).

  7. genetic association studies in population of Han Chinese in Eastern China: Using a recessive genetic model, an SNP in LTA4H (rs6538697) is associated with increased risk of ischemic stroke.

  8. Structural origins for the loss of catalytic activities of bifunctional human LTA4H revealed through molecular dynamics simulations.

  9. It was found modest association with LTA4H rs1978331C (intron 11) with increased FEV1 (p = 0.029) and with increased FEV1/FVC ratio (p = 0.020).

  10. common polymorphisms in the LTA4H gene do not play any major role in susceptibility to clinical pulmonary tuberculosis

Mouse (Murine) Leukotriene A4 Hydrolase (LTA4H) interaction partners

  1. There is a critical role for the secondary anti-inflammatory activity of LTA4H in acute pulmonary infection.

  2. CS exposure promotes the development of CS-induced emphysema by suppressing the enzymatic activities of the LTA4H aminopeptidase in lung tissues and accumulating PGP and neutrophils in the airspaces.

  3. in acute neutrophil-driven lung inflammation, PGP was degraded by LTA(4)H which facilitated resolution of inflammation; cigarette smoke, a major risk factor for COPD,inhibited LTA(4)H aminopeptidase activity leading to accumulation of PGP and neutrophils

  4. 5-lipoxygenase (show ALOX5 Antibodies) and leukotriene A4 hydrolase expression in atherosclerotic lesions correlates with symptoms of plaque instability

  5. In the mouse nervous system ,Immunoreactivity for leukotriene A4 hydrolase showed widespread distribution with preference to the sensory-associated structures.

Leukotriene A4 Hydrolase (LTA4H) Antigen Profile

Protein Summary

Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.

Gene names and symbols associated with LTA4H

  • leukotriene A4 hydrolase (LTA4H) antibody
  • leukotriene A4 hydrolase (lta4h) antibody
  • leukotriene A4 hydrolase (LOC732953) antibody
  • leukotriene A4 hydrolase (Shew185_1367) antibody
  • leukotriene A4 hydrolase (Sbal195_1406) antibody
  • leukotriene A4 hydrolase (XfasM23_0741) antibody
  • Leukotriene A4 hydrolase (Sbal223_2977) antibody
  • leukotriene A4 hydrolase (lkhA) antibody
  • leukotriene A4 hydrolase (Lta4h) antibody
  • AmpT antibody
  • DDBDRAFT_0191291 antibody
  • DDBDRAFT_0216768 antibody
  • DDB_0191291 antibody
  • DDB_0216768 antibody
  • LOC732953 antibody
  • lta4h antibody
  • MGC69197 antibody
  • MGC78867 antibody
  • zgc:85809 antibody

Protein level used designations for LTA4H

leukotriene A4 hydrolase , leukotriene A-4 hydrolase , Leukotriene A4 hydrolase , leukotriene A-4 hydrolase-like , LTA-4 hydrolase , aminopeptidase T , leukotriene A(4) hydrolase , LTA4 hydrodase , LTA4 hydrolase

GENE ID SPECIES
713038 Macaca mulatta
100017641 Monodelphis domestica
100052257 Equus caballus
100171657 Pongo abelii
100565831 Anolis carolinensis
100595121 Nomascus leucogenys
406575 Danio rerio
432332 Xenopus laevis
448745 Xenopus (Silurana) tropicalis
452145 Pan troglodytes
732953 Bombyx mori
5370072 Shewanella baltica OS185
5753135 Shewanella baltica OS195
6202962 Xylella fastidiosa M23
7089045 Shewanella baltica OS223
8617739 Dictyostelium discoideum AX4
100413464 Callithrix jacchus
4048 Homo sapiens
482611 Canis lupus familiaris
100154219 Sus scrofa
507130 Bos taurus
16993 Mus musculus
299732 Rattus norvegicus
417918 Gallus gallus
100135571 Cavia porcellus
100357727 Oryctolagus cuniculus
102007852 Chinchilla lanigera
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