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The protein encoded by LPPR4 belongs to the lipid phosphate phosphatase (LPP) family. Additionally we are shipping Lipid Phosphate Phosphatase-Related Protein Type 4 Kits (4) and many more products for this protein.
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Human Polyclonal LPPR4 Primary Antibody for EIA, WB - ABIN265080
Bräuer, Savaskan, Kühn, Prehn, Ninnemann, Nitsch: A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. in Nature neuroscience 2003
Endogenous PRG3 (show PRG3 Antibodies) promotes neurite shaft protrusion and therefore contributes to regulating filopodia formation in immature neurons.
PRG-1 (show PTGR1 Antibodies) as an important player in the modulatory control of hippocampal excitability dependent on presynaptic LPA(2 (show LPAR2 Antibodies)) receptor signaling.
LPR4 mutations alter Wnt (show WNT2 Antibodies)/beta catenin (show CTNNB1 Antibodies) signaling and cause limb and kidney malformations in Cenani-Lenz syndrome.
The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
lipid phosphate phosphatase-related protein type 4
, plasticity related gene 1
, brain-specific phosphatidic acid phosphatase-like protein 1
, plasticity-related gene 1 protein