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anti-Lipin 1 (LPIN1) Antibodies

LPIN1 represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Additionally we are shipping Lipin 1 Kits (10) and Lipin 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LPIN1 23175 Q14693
LPIN1 14245 Q91ZP3
LPIN1 313977  
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Top anti-Lipin 1 Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-LPIN1 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC (p), WB Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon labeled with Anti Lpin1 Polyclonal Antibody, Unconjugated (ABIN672831) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded mouse colon labeled with Anti Lpin1 Polyclonal Antibody, Unconjugated (ABIN672831) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-Lpin1 protein Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details
Mouse Rabbit Un-conjugated IF, ELISA, WB   50 μg Log in to see 8 to 10 Days
$610.50
Details

LPIN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Lipin 1 Antibodies

  1. Chicken Polyclonal LPIN1 Primary Antibody for WB - ABIN2785598 : Ong, Leung, Wong, Cherny, Sham, Lam, Lam, Cheung: Association of a polymorphism in the lipin 1 gene with systolic blood pressure in men. in American journal of hypertension 2008 (PubMed)

  2. Human Polyclonal LPIN1 Primary Antibody for ELISA, WB - ABIN185721 : Suviolahti, Reue, Cantor, Phan, Gentile, Naukkarinen, Soro-Paavonen, Oksanen, Kaprio, Rissanen, Salomaa, Kontula, Taskinen, Pajukanta, Peltonen: Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. in Human molecular genetics 2006 (PubMed)

More Antibodies against Lipin 1 Interaction Partners

Human Lipin 1 (LPIN1) interaction partners

  1. lipin-1 has a critical role in the regulation of macrophage inflammatory responses to modified-LDL

  2. Results of our study suggest that rs2716610: C>T polymorphism of LPIN1 gene could have a protective effect against development of metabolic syndrome, while rs11693809: C>T might affect a glucose control in patients with MS.

  3. Lipin-1 controls main cellular processes involved in cancer progression and that its targeting, alone or in combination with other treatments, could open new avenues in anticancer therapy.

  4. Lipin1beta might play a role in the pathogenesis of insulin (show INS Antibodies) resistance in gestational diabetes mellitus

  5. LPIN1 plays a functional role in lipid synthesis and storage, a role which is highly conserved from human to yeast.

  6. the lipin-1 N-terminal domain is important for its catalytic activity, nuclear localization, and binding to PP-1cgamma

  7. Lipin-1 deficiency is associated with lipid metabolism alterations resulting in massive rhabdomyolysis.

  8. the SNP in the LPIN1 gene (rs10192566) had no effect on the trough rosiglitazone steady-state concentration.

  9. Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association

  10. Data suggests common single nucleotide polymorphisms within the LPIN1 region were associated with Type 2 diabetes and metabolic traits in the Chinese population.

Mouse (Murine) Lipin 1 (LPIN1) interaction partners

  1. lipin-1 has a critical role in the regulation of macrophage inflammatory responses to modified-LDL

  2. c-fos has a role in increasing the catalytic efficiency of lipin 1 beta

  3. reveals a previously unknown role of lipin1 in skeletal muscle regeneration and expands our understanding of the cellular and molecular mechanisms underlying skeletal muscle regeneration

  4. deficits in hepatic PAP (show ASAP1 Antibodies) activity do not impair TG synthesis and accumulation

  5. lipin-1 PAP (show ASAP1 Antibodies) activity functions in autophagy to activate the PKD (show PRKD1 Antibodies)-Vps34 (show PIK3C3 Antibodies) cascade to promote autolysosome maturation.

  6. The findings demonstrate an unanticipated role for lipin-1 as a mediator of macrophage proinflammatory activation and support a critical link between lipid biosynthesis and systemic inflammatory responses.

  7. in addition to their roles during early adipogenesis, lipin1 and lipin2 (show LPIN2 Antibodies) also have a role in lipid droplet biogenesis.

  8. hepatic removal of lipin-1 in mice augmented ethanol-induced impairment of hepatic fatty acid oxidation and lipoprotein production, likely by way of deactivation of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (show PPARGC1A Antibodies).

  9. lipin1 functions as a key regulator of PPARgamma (show PPARG Antibodies) activity through its ability to release co-repressors and recruit co-activators via a mechanism other than PPARalpha (show PPARA Antibodies) activation

  10. These results suggested that ER stress might be involved inthe pathogenesis of obesity through lipin-1 depletion.

Pig (Porcine) Lipin 1 (LPIN1) interaction partners

  1. The lipin1 gene may have a crucial effect on body lipid accumulation in pigs.

  2. Different genotypes of the Lpin1 gene were associated with percentage of leaf fat and intramuscular fat.

Cow (Bovine) Lipin 1 (LPIN1) interaction partners

  1. The results of this study suggest that suggest that SLC27A6 (show SLC27A6 Antibodies), ACSL1 (show Acsl1 Antibodies), FABP3 (show FABP3 Antibodies), AGPAT6 (show AGPAT6 Antibodies), and LPIN1 coordinately regulate the channeling of fatty acids toward copious milk fat synthesis in bovine mammary.

Lipin 1 (LPIN1) Antigen Profile

Protein Summary

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

Gene names and symbols associated with anti-Lipin 1 (LPIN1) Antibodies

  • lipin 1 (LPIN1) antibody
  • lipin 1 (lpin1) antibody
  • lipin 1 (Lpin1) antibody
  • 4631420P06 antibody
  • fld antibody
  • Kiaa0188 antibody
  • lipin1 antibody
  • LPIN1 antibody
  • mKIAA0188 antibody
  • PAP1 antibody
  • zgc:194552 antibody
  • zgc:194558 antibody

Protein level used designations for anti-Lipin 1 (LPIN1) Antibodies

lipin 1 , phosphatidate phosphatase LPIN1-like , lipin-1 , phosphatidate phosphatase LPIN1 , fatty liver dystrophy protein

GENE ID SPECIES
459036 Pan troglodytes
779950 Xenopus (Silurana) tropicalis
100231657 Taeniopygia guttata
100400101 Callithrix jacchus
100458857 Pongo abelii
100465923 Ailuropoda melanoleuca
100539289 Meleagris gallopavo
100586976 Nomascus leucogenys
23175 Homo sapiens
475670 Canis lupus familiaris
14245 Mus musculus
313977 Rattus norvegicus
799099 Danio rerio
421945 Gallus gallus
100170845 Sus scrofa
537224 Bos taurus
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