Lipin 1 antibody (N-Term)

Catalog No. ABIN2785598

The Rabbit Polyclonal anti-Lipin 1 antibody (ABIN2785598) specifically detects Lipin 1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig, Saccharomyces cerevisiae, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for Lipin 1 antibody (N-Term) (ABIN2785598)

Target: Lipin 1 (LPIN1)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Lipin 1 Antibody

Binding Specificity: N-Term

Purpose: LPIN1 Antibody - N-terminal region

Sequence: SLAVIYPQSA SYPNSDREWS PTPSPSGSRP STPKSDSELV SKSTERTGQK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 91%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against LPIN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LPIN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104503

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: LPIN1

Background:

Background Information: This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mouse studies suggest that LPIN1 functions during normal adipose tissue development and may also play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mouse studies suggest that this gene functions during normal adipose tissue development and may also play a role in human triglyceride metabolism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Lipin 1

Alternative Symbols: PAP1

Protein Name: Phosphatidate phosphatase LPIN1

Molecular Weight: 98kDa

Gene ID: 23175

NCBI Accession: NP_663731

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process