anti-Lymphocyte Cytosolic Protein 1 (LCP1) Antibodies

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. Additionally we are shipping LCP1 Kits (10) and LCP1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LCP1 306071  
LCP1 18826 Q61233
LCP1 3936 P13796
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Top anti-LCP1 Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-LCP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-LCP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Plastin L Antibody [NBP1-88057] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunocytochemistry/Immunofluorescence: Plastin L Antibody [NBP1-88057] - Staining of human cell line U-2 OS shows positivity in plasma membrane, cytoplasm & cytoskeleton (actin filaments). 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
REACT_Cytomegalovirus Rabbit Un-conjugated BP, ELISA, IHC, WB CMV-pp65 staining in rat aortic endothelium. Paraffin-embedded rat aorta is stained with CMV-pp65 Antibody used at 1:400 dilution. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Plastin L Antibody [NBP2-19861] - Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using antibody at 1:500 dilution. Western Blot: Plastin L Antibody [NBP2-19861] - Sample (30 ug of whole cell lysate) A: JurKat 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB Immunohistochemistry-Paraffin: Plastin L Antibody [NBP2-19860] - Immunohistochemical analysis of paraffin-embedded RF48 xenograft, using antibody at 1:500 dilution. Immunocytochemistry/Immunofluorescence: Plastin L Antibody [NBP2-19860] - Sample: A431 cells were fixed in -20C 100% MeOH for 5 min. Green: LCP1 protein stained by L-Plastin antibody diluted at 1:500. Blue: Hoechst 33343 staining. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 16 Days
$334.02
Details
Human Rabbit Un-conjugated WB LCP1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the LCP1 antibody detected the LCP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

LCP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LCP1 Antibodies

  1. Cytomegalovirus (CMV) Polyclonal LCP1 Primary Antibody for BP, ELISA - ABIN1586192 : Flinsenberg, Compeer, Koning, Klein, Amelung, van Baarle, Boelens, Boes: Fc? receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells. in Blood 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal LCP1 Primary Antibody for ICC, IF - ABIN4346103 : Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014 (PubMed)

More Antibodies against LCP1 Interaction Partners

Mouse (Murine) Lymphocyte Cytosolic Protein 1 (LCP1) interaction partners

  1. the actin-bundling protein L-plastin (LPL) is required for the perinatal development of alveolar macrophages.

  2. Results identify L-plastin as a key effector of Mst1 (show MST1 Antibodies) and establish a novel mechanism linking a signaling intermediate to an actin-binding protein (show PFN1 Antibodies) critical to T cell migration.

  3. L-plastin modulates both T- and B-cell function during the germinal center reaction and the production of T-cell-dependent antibody responses.

  4. L-plastin may participate in signaling that enables lymphocyte transmigration

  5. LPL-dependent actin bundling facilitates the formation of lamellipodia and normal immunological synapses and thereby enables T cell activation.

  6. Regulation of sealing ring formation by L-plastin and cortactin (show CTTN Antibodies) in osteoclasts.

  7. We thus identify L-plastin as a molecule critical for CCR7 (show CCR7 Antibodies)-mediated t-cell motility but dispensable for early CCR7 (show CCR7 Antibodies) signaling.

Human Lymphocyte Cytosolic Protein 1 (LCP1) interaction partners

  1. AngII-dependent phosphorylation of LCP1 in cultured podocytes was mediated by the kinases ERK (show EPHB2 Antibodies), p90 (show CANX Antibodies) ribosomal S6 kinase (show RPS6KB1 Antibodies), PKA, or PKC (show PRRT2 Antibodies). LCP1 phosphorylation increased filopodia formation.

  2. L-plastin regulates the stability of the immune synapse of naive and effector T-cells. (Review)

  3. The findings support a mechanism in which miR (show MLXIP Antibodies)-375 suppresses RUNX1 (show RUNX1 Antibodies) levels, resulting in reduced vimentin (show VIM Antibodies) and L-plastin expression. Knockdown of RUNX1 (show RUNX1 Antibodies), L-plastin, and vimentin (show VIM Antibodies) resulted in significant reductions in cell invasion in vitro, indicating the functional significance of miR (show MLXIP Antibodies)-375 regulation of specific proteins involved in head and neck squamous cell carcinoma (HNSCC) invasion.

  4. In this study, the authors found that the actin filament bundling abilities of PLS1 (show PLS1 Antibodies) and PLS2 were similarly sensitive to Ca(2 (show CA2 Antibodies)+) (pCa50 ~6.4), whereas PLS3 (show PLS3 Antibodies) was less sensitive (pCa50 ~5.9).

  5. elevated L-plastin expression promotes elongation and reduces protrusion density in cells with relatively lower L-plastin than fascin (show FSCN1 Antibodies) levels.

  6. Enhanced nitroxidative stress may results in LPL S-glutathionylation leading to impaired chemotaxis, polarization, and bactericidal activity of human neutrophils.

  7. association of SNPs in LCP1 and CTIF (show KIAA0427 Antibodies) with hearing

  8. An NKX3.1 (show NKX3-1 Antibodies) binding site polymorphism in the l-plastin promoter leads to differential gene expression in human prostate cancer

  9. The proteins (HSP90b (show HSP90AB1 Antibodies), TSM1 and L-plastin) in the current study may hold potential in differentiating between melanoma and benign nevi in diagnostically challenging cases.

  10. Data suggest that several single-nucleotide polymorphisms (SNPs) of the plastin genes PLS3 (show PLS3 Antibodies) and LCP1 could serve as gender- and/or stage-specific molecular predictors of tumor recurrence in stage II/III colorectal cancer as well as therapeutic targets.

LCP1 Antigen Profile

Protein Summary

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

Gene names and symbols associated with LCP1

  • lymphocyte cytosolic protein 1 (L-plastin) (lcp1) antibody
  • lymphocyte cytosolic protein 1 (Lcp1) antibody
  • lymphocyte cytosolic protein 1 (LCP1) antibody
  • lymphocyte cytosolic protein 1 (L-plastin) S homeolog (lcp1.S) antibody
  • TOX high mobility group box family member 4 (Tox4) antibody
  • 5730589K01Rik antibody
  • A630040M18 antibody
  • AA410149 antibody
  • AW536232 antibody
  • cb245 antibody
  • cp64 antibody
  • D14Ertd310e antibody
  • fj24b12 antibody
  • l-plastin antibody
  • lc64p antibody
  • LCP-1 antibody
  • LCP1 antibody
  • lpl antibody
  • plastin-2 antibody
  • pls2 antibody
  • pp65 antibody
  • wu:fj24b12 antibody

Protein level used designations for LCP1

L-plastin , leucocyte-specific plastin 1 , plastin-2 , 65 kDa macrophage protein , L-fimbrin , L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65) , plastin 2, L , L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P) , LCP-1 , Lymphocyte cytosolic protein-1 (plasmin) , bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)) , plastin 2 , epidermal Langerhans cell protein LCP1

GENE ID SPECIES
30583 Danio rerio
306071 Rattus norvegicus
18826 Mus musculus
3936 Homo sapiens
379911 Xenopus laevis
418852 Gallus gallus
476921 Canis lupus familiaris
540990 Bos taurus
268741 Mus musculus
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