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Lysophosphatidic Acid Receptor 4 Proteins (LPAR4)

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Additionally we are shipping LPAR4 Antibodies (61) and LPAR4 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LPAR4 2846 Q99677
LPAR4 78134 Q8BLG2
Rat LPAR4 LPAR4 302378  
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Top LPAR4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

LPAR4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Lysophosphatidic Acid Receptor 4 (LPAR4) Interaction Partners

Human Lysophosphatidic Acid Receptor 4 (LPAR4) interaction partners

  1. These results suggest that the diverse roles of LPA4, LPA5 (show LPAR5 Proteins) and LPA6 (show LPAR6 Proteins) are involved in the activation of tumor progression in pancreatic cancer cells.

  2. Our data suggest that LPA4 signaling potentially modulates malignant behavior of SQ-20B cells.

  3. LPA4 gene mutation may play some role in the pathogenesis of colon cancer.

  4. LPA4 and LPA5 (show LPAR5 Proteins) receptors induce osteoblastic differentiation of human mesenchymal stem cells

  5. Data show that CLL cells express LPA receptors LPA(1-5) and VEGF receptors, and the plasma levels of VEGF are elevated in CLL patients.

  6. identified as the fourth lysophosphatidic acid (LPA (show APOA Proteins)) receptor; shares only 20-24% amino acid identities with Edg-2/LPA1 (show LPAR1 Proteins), Edg-4/LPA2 (show LPAR2 Proteins), and Edg-7/LPA3 (show LPAR3 Proteins), and phylogenetic analysis also shows that p2y9/GPR23 is far distant from the Edg family

Mouse (Murine) Lysophosphatidic Acid Receptor 4 (LPAR4) interaction partners

  1. The lysophosphatidic acid receptor LPA4 regulates hematopoiesis-supporting activity of bone marrow stromal cells

  2. These results suggest that LPA(4) regulates establishment of the structure and function of blood and lymphatic vessels during mouse embryogenesis

  3. Affymetrix expression profiling shows that the C terminus of Runx2 (show RUNX2 Proteins) regulates genes involved in G protein-coupled receptor (show GPR34 Proteins) signaling Rgs2 (show RGS2 Proteins), Rgs4 (show RGS4 Proteins), Rgs5 (show RGS5 Proteins), Rgs16 (show RGS16 Proteins), Gpr23, Gpr30, Gpr54, Gpr64, and Gna13 (show GNA13 Proteins).

  4. a direct role for LPA receptor signaling in cell transformation and tumorigenesis in conjunction with c-Myc (show MYC Proteins)

  5. These results provide genetic and biochemical evidence that LPA(4) is a suppressor of LPA-dependent cell migration and invasion in contrast to the motility-stimulating Edg LPA receptors.

LPAR4 Protein Profile

Protein Summary

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA.

Gene names and symbols associated with LPAR4

  • lysophosphatidic acid receptor 4 (LPAR4)
  • lysophosphatidic acid receptor 4 (lpar4)
  • lysophosphatidic acid receptor 4 (Lpar4)
  • 5730485F04Rik protein
  • Gpr23 protein
  • LPA4 protein
  • P2RY9 protein
  • P2Y5-LIKE protein
  • p2y9 protein
  • RGD1563686 protein

Protein level used designations for LPAR4

G protein-coupled receptor 23 , G-protein coupled receptor 23 , LPA receptor 4 , LPA-4 , P2Y purinoceptor 9 , P2Y5-like receptor , purinergic receptor 9

GENE ID SPECIES
422149 Gallus gallus
539738 Bos taurus
779407 Xenopus laevis
780308 Xenopus (Silurana) tropicalis
465729 Pan troglodytes
491978 Canis lupus familiaris
2846 Homo sapiens
78134 Mus musculus
302378 Rattus norvegicus
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