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anti-MYC Binding Protein 2 (MYCBP2) Antibodies

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.

list all antibodies Gene Name GeneID UniProt
MYCBP2 105689 Q7TPH6
MYCBP2 23077 O75592
MYCBP2    
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Top anti-MYCBP2 Antibodies at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Alexa Fluor 555 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy5 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy3 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit HRP IHC (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy5.5 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details

MYCBP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human ,


, , , , , , , , , , ,
Rat (Rattus) ,


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More Antibodies against MYCBP2 Interaction Partners

Mouse (Murine) MYC Binding Protein 2 (MYCBP2) interaction partners

  1. nuclear localization of Ran was strongly increased in MYCBP2-deficient DRGs

  2. Arf-bp1 and Pam (show PAM Antibodies) are novel regulators of circadian gene expression that target Rev-erb alpha (show NR1D1 Antibodies) for degradation

  3. Mycbp2 and Robo2 (show ROBO2 Antibodies) were found to cooperate within a genetic network that has profound effects on axon guidance

  4. Phr1 (show PLEKHB1 Antibodies) is identified as a key regulator of a core axon degeneration program that balances axon survival and loss in various neuronal cell types.

  5. The ubiquitin ligase (show RNF123 Antibodies) complex containing Pam (show PAM Antibodies)-Fbxo45 (show FBXO45 Antibodies) likely targets additional synaptic and axonal proteins, which may explain the overlapping neurodevelopmental defects observed in Phr1 (show PLEKHB1 Antibodies) and Fbxo45 (show FBXO45 Antibodies) deficiency.

  6. These results show that Phr1 (show PLEKHB1 Antibodies) is an essential regulator of retinal ganglion cell projection during both dLGN and SC topographic map development.

  7. p38 MAPK (show MAPK14 Antibodies) activation can inhibit activity-induced ion channel internalization and MYCBP2 regulates internalization of TRPV1 (show TRPV1 Antibodies) in peripheral sensory neurons as well as duration of thermal hyperalgesia through p38 MAPK (show MAPK14 Antibodies)

  8. Structures of both the first and second PHR domains of Mus (show TRPV6 Antibodies) musculus (mouse) Phr1 (MYC binding protein 2, Mycbp2) have been determined, revealing a novel beta sandwich fold composed of 11 antiparallel beta-strands.

  9. Phr1 (show PLEKHB1 Antibodies) is required for formation of major CNS axon tracts via a mechanism that is both cell-nonautonomous and independent of DLK (show DAPK3 Antibodies).

  10. Thus, efficacious pathfinding requires Phr1 (show PLEKHB1 Antibodies) activity for coordinating the cytoskeletal organization that distinguishes axons from growth cones.

Human MYC Binding Protein 2 (MYCBP2) interaction partners

  1. Data indicate an oncogenic role for an Ikaros (show IKZF1 Antibodies) protein/MYCBP2 protein/proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-MYC (show MYC Antibodies) axis in adult acute lymphoblastic leukemia (ALL), providing a mechanism of target therapies that activate Ikaros (show IKZF1 Antibodies) in ALL.

  2. Arf-bp1 (show HUWE1 Antibodies) and Pam (show PAM Antibodies) are novel regulators of circadian gene expression that target Rev-erb alpha (show NR1D1 Antibodies) for degradation

  3. Data show that epithelial-mesenchymal transition (EMT (show ITK Antibodies))-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1 (show SKP1 Antibodies)-Pam (show PAM Antibodies)-Fbxo45 (show FBXO45 Antibodies) (SPFFbxo45).

  4. In castration resistant prostate cancer, MYCBP2 is down-regulated at the mRNA and protein levels.

  5. We describe a distinct excavated optic disc anomaly associated with high myopia and increased axial length. The condition appears to follow an autosomal dominant pattern and segregate with a deletion in MYCBP2.

  6. Pam (show PAM Antibodies), through its interaction with tuberin (show TSC2 Antibodies), could regulate the ubiquitination and proteasomal degradation of the tuberin (show TSC2 Antibodies)-hamartin (show TSC1 Antibodies) complex particularly in the CNS

  7. PAM (show PAM Antibodies) the longest lasting nontranscriptional regulator of adenylyl cyclase activity known to date and presents a novel mechanism for the temporal regulation of cAMP signaling

  8. Identifies the region in PAM (show PAM Antibodies) that inhibits the domain of type V adenylyl cyclase.

  9. PAM (show PAM Antibodies) protein activated by facilitating the GDP/GTP (show AK3 Antibodies)-exchange of RHEBL1 (show RHEBL1 Antibodies) protein which is an activator of mTOR (show FRAP1 Antibodies) protein.

MYCBP2 Antigen Profile

Protein Summary

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis.

Gene names and symbols associated with MYCBP2

  • MYC binding protein 2 (Mycbp2) antibody
  • MYC binding protein 2, E3 ubiquitin protein ligase (MYCBP2) antibody
  • AU023734 antibody
  • AW107953 antibody
  • AW546647 antibody
  • C130061D10Rik antibody
  • PAM antibody
  • Phr1 antibody
  • R75243 antibody

Protein level used designations for MYCBP2

Myc-binding protein 2 , pam, highwire, rpm 1 , pam/highwire/rpm-1 protein , probable E3 ubiquitin-protein ligase MYCBP2 , protein associated with Myc , myc-binding protein 2

GENE ID SPECIES
105689 Mus musculus
23077 Homo sapiens
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