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MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. Additionally we are shipping Macrophage Scavenger Receptor 1 Antibodies (231) and Macrophage Scavenger Receptor 1 Proteins (15) and many more products for this protein.
Showing 9 out of 21 products:
Human Macrophage Scavenger Receptor 1 ELISA Kit for Sandwich ELISA - ABIN417678
Zuo, Yu, Guo, Wang, Qian, Yi, Lu, Lv, Subjeck, Zhou, Sanyal, Chen, Wang: Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury. in Hepatology (Baltimore, Md.) 2013
We also demonstrate that across the human genome, the presence of MSR1 repeats in the promoters or first introns of genes is associated with greater population variability in gene expression indicating that copy number variation of MSR1s is a generic controller of gene expression and promises to provide new insights into our understanding of gene expression regulation
Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO (show MARCO ELISA Kits).
The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.
Cyr61 (show CYR61 ELISA Kits) promotes CD204 expression and the migration of macrophages via MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) pathway in esophageal squamous cell carcinoma
miR (show MLXIP ELISA Kits)-29a promotes scavenger receptor A expression by targeting QKI (show QKI ELISA Kits) during monocyte-macrophage differentiation.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP ELISA Kits) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP ELISA Kits) oligomer in microglia.
The truncating variant Arg293X in the gene encoding SRA (show SRA1 ELISA Kits)-I/II was associated with reduced lung function and with increased risk of COPD (show ARCN1 ELISA Kits) among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase (show SOD1 ELISA Kits)-3 E1I1 heterozygotes.
monomeric collagen type I via CD204 induces phospho-Akt (show AKT1 ELISA Kits) expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.
There was a significant negative correlation between the number of CD163 (show CD163 ELISA Kits)(+), CD204(+) or CD206 (show MRC1 ELISA Kits)(+) alveolar macrophages.
rs6966 (3' UTR of PPP1R13L, chr 19q13.32, P = 4.55 x 10(-9)) and rs414580 (intron 2 of MSR1, chr 8p22, P = 6.09 x 10(-8)) were significantly associated with ALL.
this study shows that Msr1 functions as co-receptor along with TLRs for HMGB1 (show HMGB1 ELISA Kits) in M1-type inflammatory macrophages
Our findings demonstrated that ClC-3 (show CLCN3 ELISA Kits) deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (show MAPK8 ELISA Kits)/p38 MAPK (show MAPK14 ELISA Kits) dependent SR-A expression and foam cell formation
FAP (show FAP ELISA Kits)-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.
Macrophages regulate FX plasma levels in an SR-AI-dependent manner.
The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.
these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.
Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP ELISA Kits) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP ELISA Kits) oligomer in an immortalized microglia cell line.
SR-A does not induce cytokine production, but mediates inhibition of LPS (show TLR4 ELISA Kits)-stimulated production of IL-6 (show IL6 ELISA Kits) and IL-12 (show IL12A ELISA Kits)
The antagonism between SR-A and RAGE (show AGER ELISA Kits) contributes to the pathogenesis of diabetic retinopathy by nurturing a disease-prone macrophage phenotype.
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
macrophage scavenger receptor 1
, macrophage scavenger receptor types I and II-like
, macrophage acetylated LDL receptor I and II
, macrophage scavenger receptor type III
, macrophage scavenger receptor types I and II
, scavenger receptor class A member 1
, scavenger receptor class A, member 1
, scavenger receptor type A
, macrophage scavenger receptor type I