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MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. Additionally we are shipping Macrophage Scavenger Receptor 1 Antibodies (234) and Macrophage Scavenger Receptor 1 Proteins (16) and many more products for this protein.
Showing 10 out of 22 products:
Human Macrophage Scavenger Receptor 1 ELISA Kit for Sandwich ELISA - ABIN417678
Zuo, Yu, Guo, Wang, Qian, Yi, Lu, Lv, Subjeck, Zhou, Sanyal, Chen, Wang: Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury. in Hepatology (Baltimore, Md.) 2013
SR-A1 suppresses lung cancer metastasis by downregulating SAA1 (show SAA1 ELISA Kits) production in tumor-associated macrophages (TAM (show CCNA1 ELISA Kits)).
PTX2 (show APCS ELISA Kits) was identified PTX2 (show APCS ELISA Kits) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.
we found that higher percentages of circulating CD14 (show NDUFA2 ELISA Kits)+CD204+, CD14 (show NDUFA2 ELISA Kits)+CD163 (show CD163 ELISA Kits)+CD204+ M2-like monocytes were significantly associated with TNM (show ODZ1 ELISA Kits) stage, lymph node metastasis, and histological differentiation.
Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO (show MARCO ELISA Kits).
The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.
Cyr61 (show CYR61 ELISA Kits) promotes CD204 expression and the migration of macrophages via MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) pathway in esophageal squamous cell carcinoma
miR (show MLXIP ELISA Kits)-29a promotes scavenger receptor A expression by targeting QKI (show QKI ELISA Kits) during monocyte-macrophage differentiation.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP ELISA Kits) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP ELISA Kits) oligomer in microglia.
The truncating variant Arg293X in the gene encoding SRA (show SRA1 ELISA Kits)-I/II was associated with reduced lung function and with increased risk of COPD (show ARCN1 ELISA Kits) among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase (show SOD1 ELISA Kits)-3 E1I1 heterozygotes.
monomeric collagen type I via CD204 induces phospho-Akt (show AKT1 ELISA Kits) expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.
Data (including data from studies conducted in cells from knockout mice) suggest that signaling via Lpar1 (show LPAR1 ELISA Kits), Cd14 (show CD14 ELISA Kits), and Scara1 mediates uptake of oxidized LDL by macrophages leading to foam cell formation; lysophosphatidic acid (LPA) induces expression of Cd14 (show CD14 ELISA Kits) and Scara1 in macrophages. (Lpar1 (show LPAR1 ELISA Kits) = LPA receptor 1 (show LPAR1 ELISA Kits); Cd14 (show CD14 ELISA Kits) = monocyte differentiation antigen CD14 (show CD14 ELISA Kits); Scara1 = scavenger receptor class A type I)
Common damage-associated molecular patterns (DAMPs) were internalized through the class A scavenger receptors MSR1 and MARCO (show MARCO ELISA Kits) in vitro. In ischemic murine brain, DAMP (show AMPH ELISA Kits) internalization was largely mediated by MSR1. Combined deficiency for Msr1 and Marco (show MARCO ELISA Kits) in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.
PTX2 (show PITX2 ELISA Kits) was identified PTX2 (show PITX2 ELISA Kits) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.
this study shows that Msr1 functions as co-receptor along with TLRs for HMGB1 (show HMGB1 ELISA Kits) in M1-type inflammatory macrophages
Our findings demonstrated that ClC-3 (show CLCN3 ELISA Kits) deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (show MAPK8 ELISA Kits)/p38 MAPK (show MAPK14 ELISA Kits) dependent SR-A expression and foam cell formation
FAP (show FAP ELISA Kits)-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.
Macrophages regulate FX plasma levels in an SR-AI-dependent manner.
The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.
these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.
Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
macrophage scavenger receptor 1
, macrophage scavenger receptor types I and II-like
, macrophage acetylated LDL receptor I and II
, macrophage scavenger receptor type III
, macrophage scavenger receptor types I and II
, scavenger receptor class A member 1
, scavenger receptor class A, member 1
, scavenger receptor type A
, macrophage scavenger receptor type I