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HLA-B belongs to the HLA class I heavy chain paralogues. Additionally we are shipping HLA-B Proteins (74) and HLA-B Kits (4) and many more products for this protein.
Showing 10 out of 128 products:
Human Polyclonal HLA-B Primary Antibody for WB - ABIN1944779
Little, Parham: The HLA-Bw75 subtype of B15: molecular characterization and comparison with crossreacting antigens. in Tissue antigens 1992
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Human Polyclonal HLA-B Primary Antibody for WB - ABIN516466
Lorente, García, López: Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells. in The Journal of biological chemistry 2011
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Human Polyclonal HLA-B Primary Antibody for IHC, WB - ABIN3021869
Parham, Lomen, Lawlor, Ways, Holmes, Coppin, Salter, Wan, Ennis: Nature of polymorphism in HLA-A, -B, and -C molecules. in Proceedings of the National Academy of Sciences of the United States of America 1988
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Human Polyclonal HLA-B Primary Antibody for FACS, IHC (p) - ABIN652557
Guild, Strominger: Human and murine class I MHC antigens share conserved serine 335, the site of HLA phosphorylation in vivo. in The Journal of biological chemistry 1984
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Human Polyclonal HLA-B Primary Antibody for WB - ABIN654636
Noble, Valdes, Varney, Carlson, Moonsamy, Fear, Lane, Lavant, Rappner, Louey, Concannon, Mychaleckyj, Erlich,: HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. in Diabetes 2010
The results suggest that HLA-B*44:03 or other closely linked gene of the major histocompatibility complex is associated with susceptibility to the development of postherpetic neuralgia after herpes zoster, but not with the onset of herpes zoster.
The effect of patient and/or donor HLA-B*51:01 on acute graft-versus-host disease was attributed not only to strong linkage disequilibrium of HLA-C* 14:02 and HLA-B*51:01, but also to the effect of HLA-B*51:01 itself.
Data indicate that human platelet antigen (HPA) 1-16 and human leukocyte antigen (HLA)-A and -B are highly polymorphic among ethnic Hans from Shandong, China.
HLA-B27 positivity and smoking are associated with a chondro-proliferative metabolic pattern in disease modifying antirheumatic agent-naive axial spondyloarthritis patients.
Results showed that certain alleles of HLA, particularly HLA-B*56:02, were significantly associated with phenytoin-related Stevens-Johnson syndrome in the study population.
These data indicate that HLA-B*57:01 carriage confers higher risk of ALT elevation in patients receiving pazopanib and provide novel insight implicating an immune-mediated mechanism for pazopanib-associated hepatotoxicity in some patients.
These results demonstrate diverse spatiotemporal expression patterns for MHC class I molecules in the prenatal human CNS.
Study replicated the HLA-B*27 association with acute anterior uveitis , and confirmed that HLA-B*27 homozygosity further increases the risk of AAU almost twofold.
a strong association between HLA-B*59:01 and methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in the Han Chinese population
The findings of this study do not confirm previous studies showing an evident association between mild cADR from carbamazepine and HLA-A*31:01.
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
major histocompatibility complex, class I, B
, HLA class I histocompatibility antigen, B alpha chain
, MHC Class I HLA heavy chain
, MHC HLA-B cell surface glycoprotein
, MHC HLA-B transmembrane glycoprotein
, MHC class I antigen GN00104
, MHC class I antigen HLA-B heavy chain
, MHC class I antigen SHCHA
, leukocyte antigen class I-B
, lymphocyte antigen