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Makorin Ring Finger Protein 1 Proteins (MKRN1)

The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Additionally we are shipping MKRN1 Antibodies (72) and MKRN1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MKRN1 23608 Q9UHC7
Rat MKRN1 MKRN1 296988  
MKRN1 54484  
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Top MKRN1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Macropus eugenii His tag   1 mg Log in to see 56 to 66 Days
$3,349.50
Details

MKRN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Makorin Ring Finger Protein 1 (MKRN1) Interaction Partners

Human Makorin Ring Finger Protein 1 (MKRN1) interaction partners

  1. In combination testing, MKRN1 + HPV showed the highest sensitivity and specificity levels. The MKRN1 biomarker may be a useful adjunct in primary cervical cytology screening.

  2. EGFR (show EGFR Proteins)/PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins)-mediated ubiquitination and degradation of PTEN are dependent on the MKRN1 E3 ligase.

  3. Results verified MKRN1 as an ubiquitin E3 ligase of p14ARF, it potentially regulates cellular aging and tumorigenesis in gastric cancer.

  4. MKRN1 could induce WNV capsid protein ubiquitination and degradation in a proteasome-dependent manner

  5. MKRN1 may represent a nuclear protein with multiple nuclear functions, including regulating RNA polymerase II-catalyzed transcription.

  6. Data indicate that MKRN1 is a novel modulator of p53 (show TP53 Proteins) and p21 (show CDKN1A Proteins), preferentially leading cells to p53 (show TP53 Proteins)-dependent apoptosis by suppressing p21 (show CDKN1A Proteins).

  7. Makorin 1 is a novel SEREX antigen of esophageal squamous cell carcinoma

Mouse (Murine) Makorin Ring Finger Protein 1 (MKRN1) interaction partners

  1. Systems-level analyses support a role for the E3 ligase MKRN1 as a ribonucleoprotein within the embryonic stem cell gene regulatory network

  2. MKRN1 is an elusive PPARgamma (show PPARG Proteins) E3 ligase that targets PPARgamma (show PPARG Proteins) for proteasomal degradation by ubiquitin-dependent pathways, and further depict MKRN1 as a novel target for diseases involving PPARgamma (show PPARG Proteins).

  3. Mutagenesis reduces transcription of Makorin1-pseudogene, resulting in destabilization of Makorin1 mRNA in trans by way of a cis (show CISH Proteins)-acting RNA decay element within the 5' region of Makorin1 that is homologous between Makorin1 and Makorin1-pseudogene

  4. Mkrn1-p1 is not imprinted, and neither it or its source Mkrn1 gene relates to the original imprinted transgene phenotype

  5. Makorin 1 is a novel SEREX antigen of esophageal squamous cell carcinoma

MKRN1 Protein Profile

Protein Summary

The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000

Gene names and symbols associated with MKRN1

  • makorin ring finger protein 1 (MKRN1)
  • MGC84269 protein (MGC84269)
  • makorin ring finger protein 1 (Mkrn1)
  • makorin, ring finger protein, 1 (Mkrn1)
  • Makorin-1 protein
  • MGC84269 protein
  • mkrn1 protein
  • RFP protein
  • RNF61 protein

Protein level used designations for MKRN1

makorin ring finger protein 1 , makorin, ring finger protein, 1 , E3 ubiquitin-protein ligase makorin-1-like , e3 ubiquitin-protein ligase makorin-1-like , MGC84269 protein , makorin 1 , E3 ubiquitin-protein ligase makorin-1 , RING finger protein 61

GENE ID SPECIES
463778 Pan troglodytes
716752 Macaca mulatta
100065893 Equus caballus
100393879 Callithrix jacchus
100440464 Pongo abelii
100480808 Ailuropoda melanoleuca
100581949 Nomascus leucogenys
444671 Xenopus laevis
395500 Gallus gallus
23608 Homo sapiens
475528 Canis lupus familiaris
514986 Bos taurus
296988 Rattus norvegicus
54484 Mus musculus
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