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The membrane-associated protein encoded by Mod2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping and many more products for this protein.
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MDR1 (show TBC1D9 Antibodies) gene could be activated via epigenetic mechanisms with demethylation of Line-1 in esophageal squamous cell carcinoma, and enhance tumor progression.
ABCB1 (show ABCB1 Antibodies) polymorphisms were associated with the risk for osteonecrosis of the femoral head.
IHC staining of human BCa (show BLNK Antibodies) tissue supported our conclusion that the expression of HIF-1a (show HIF1A Antibodies) and MDR1 (show TBC1D9 Antibodies) was higher in chemoresistant tissue vs. chemosensitive tissue.
The pharmacokinetics of silibinin was significantly influenced by ABCB1 (show ABCB1 Antibodies) C3435T polymorphism.
The results of this study suggested that the treatment of major depressive disorder can be optimized by ABCB1 (show ABCB1 Antibodies) genotyping combined with monitoring of plasma drug concentrations.
Findings indicated that fetuses of mothers with MDR1 (show TBC1D9 Antibodies) TT genotype may be more susceptible to arsenic toxicity as compared to those of CC or CT genotypes.
The ABCB1 variants modulate therapeutic response to modafinil and may partly explain pharmacoresistance in NT1 patients.
The association of rs2032588 with antidepressant side effects suggests the involvement of the ABCB1 genotype in the clinical pharmacology of PGP-dependent antidepressants.
In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCA4 Antibodies) B1 by the HMG-CoA reductase (show HMGCR Antibodies) inhibitor simvastatin
MDR1 (show TBC1D9 Antibodies) gene rs1045642 C > T might confer an increase risk for ulcerative colitis.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
malic enzyme complex, mitochondrial
, malic enzyme, mitochondrial regulatory
, malic enzyme, mitochondrial structural
, P-glycoprotein 1
, colchicin sensitivity
, doxorubicin resistance
, multidrug resistance protein 1