anti-Matrix Gla Protein (MGP) Antibodies

The protein encoded by MGP is secreted and likely acts as an inhibitor of bone formation. Additionally we are shipping Matrix Gla Protein Kits (47) and Matrix Gla Protein Proteins (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MGP 4256 P08493
MGP 17313 P19788
MGP 25333 P08494
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Top anti-Matrix Gla Protein Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: MGP Antibody [NBP1-86465] - Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemistry: MGP Antibody (11G6) [NBP2-45844] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0) Immunohistochemistry: MGP Antibody (11G6) [NBP2-45844] - Analysis of Human lung tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using MGP antibody. Immunohistochemistry of paraffin-embedded rat brain using MGP antibody at dilution of 1:100 (40x lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$332.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 15 to 18 Days
$342.00
Details
Rat Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$360.00
Details
Rat Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 15 to 18 Days
$362.00
Details

MGP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Matrix Gla Protein Antibodies

  1. Cow (Bovine) Polyclonal MGP Primary Antibody for IHC, WB - ABIN2784506 : Yao, Shahbazian, Boström: Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4. in Circulation research 2008 (PubMed)

  2. Human Polyclonal MGP Primary Antibody for IHC, IHC (p) - ABIN4334178 : Lorenzen, Martino, Scheffner, Bröcker, Leitolf, Haller, Gwinner: Fetuin, matrix-Gla protein and osteopontin in calcification of renal allografts. in PLoS ONE 2013 (PubMed)

More Antibodies against Matrix Gla Protein Interaction Partners

Xenopus laevis Matrix Gla Protein (MGP) interaction partners

  1. Usefulnees of nonmammalian model systems to elucidate the complex regulation of MGP gene transcription.

  2. These data also indicate that MGP is under dual regulation by runx2 (show RUNX2 Antibodies) through the use of various isoforms and context-dependent formation of transcriptional complexes.

Zebrafish Matrix Gla Protein (MGP) interaction partners

  1. MGP is a multi-functional inhibitor of normal and abnormal angiogenesis that may function by coordinating with both Notch and BMP signaling pathways

  2. In contrast with results obtained for previously studied marine fishes, in zebrafish and Senegal sole Mgp accumulates in both calcified tissues and non-mieralized vessel walls of the vascular system.

Human Matrix Gla Protein (MGP) interaction partners

  1. Genetic variability in the MGP gene was associated with vascular recurrence in the Spanish population.

  2. MGP is significantly repressed by miR (show MLXIP Antibodies)-155 in breast cancer MCF-7 cells, and concomitantly there is a stimulation of cell proliferation and cell invasiveness.

  3. ectopic expression of Mgp in murine and human osteosarcoma cells led to a marked increase in lung metastasis. Abrogation of Mgp prevented lung metastatic activity, an effect that was rescued by forced expression. Mgp levels dramatically altered endothelial adhesion, trans-endothelial migration in vitro and tumour cell extravasation ability in vivo

  4. MGP rs4236 [A/G] gene polymorphism was not to be associated with subgingival dental calculus. Also, that GCF (show GUCY2F Antibodies) MGP levels were detected higher in patients with subgingival dental calculus than those without subgingival dental calculus independently of polymorphism, may be the effect of adaptive mechanism to inhibit calculus formation.

  5. The substitution of threonine by alanine due to MGP exon 4 Thr83Ala polymorphism is related to a decrease in the likelihood of arterial calcification in female persons in the Ukrainian population

  6. Correlations of plasma desphosphorylated uncarboxylated matrix Gla protein (dp-ucMGP) with vascular calcification and vascular stiffness in chronic kidney disease. Plasma dp-ucMGP was positively associated with vascular calcification and might be utilized as an early marker for vascular calcification in CKD patients.

  7. It is assumed that Lp-PLA2 (show Lp-PLA2 Antibodies) is involved in vascular calcification and that dp-ucMGP is a more appropriate biomarker of residual risk than Lp-PLA2 (show Lp-PLA2 Antibodies) itself.

  8. Data shoed increased GAS6 (show GAS6 Antibodies) and decreased MGP levels in hemodialysis patients, as mediators of induction or prevention of vascular calcification.

  9. Altering NOTCH1 (show NOTCH1 Antibodies) levels affected MGP mRNA and protein.

  10. Uncarboxylated MGP in synovial fluid might serve as a novel biomarker for assessing knee osteoarthritis progression.

Mouse (Murine) Matrix Gla Protein (MGP) interaction partners

  1. We propose MGP as a strong candidate for the regulation of stiffness in glaucoma. MGP further illustrates the presence of a common function affecting key glaucomatous parameters in the front and back of the eye, and thus offers the possibility for a sole therapeutic target for the disease.

  2. the nasal septum to be abnormally mineralized and shortened in Mgp(-/-) mice. Transgenic restoration of Mgp expression in chondrocytes fully corrected the craniofacial anomalies caused by MGP deficiency, suggesting a local role for MGP in the developing nasal septum.

  3. loss of MGP causes dysregulation of early endothelial differentiation.

  4. Matrix Gla protein limits pulmonary arteriovenous malformations in ALK1 (show ACVRL1 Antibodies) deficiency.

  5. expression of MGP and OCN increased gradually in the murine developing tibial epiphysis, and the two mineral-associated proteins may occur at the same location during a particular period, but at different levels.

  6. Elastin (show ELN Antibodies) haploinsufficiency impedes the progression of arterial calcification in MGP-deficient mice.

  7. The arterial calcification, not MGP deficiency itself, causes the low bone mass phenotype in Mgp-/- mice.

  8. Two sides of MGP null arterial disease: chondrogenic lesions dependent on transglutaminase 2 (show TGM2 Antibodies) and elastin (show ELN Antibodies) fragmentation associated with induction of adipsin (show CFD Antibodies).

  9. MGP is a multi-functional inhibitor of normal and abnormal angiogenesis that may function by coordinating with both Notch and BMP signaling pathways

  10. Mgp gene deletion may have a role in arteriovenous malformations

Pig (Porcine) Matrix Gla Protein (MGP) interaction partners

  1. High DNA methylation (show HELLS Antibodies) resulting in the down regulation of matrix Gla protein is associated with osteochondrosis.

Cow (Bovine) Matrix Gla Protein (MGP) interaction partners

  1. Selective CaSR (show CASR Antibodies) activation, either by extracellular calcium or AMG (show AMELX Antibodies) 641, increased MGP expression in vivo in the arterial wall and in vitro in bovine vascular smooth muscle cells.

  2. the effect of MGP on calcification and osteogenic differentiation is determined by availability of BMP-2 (show BMP2 Antibodies)

  3. MGP plays a role in endothelial cell function, by increasing transforming growth factor-beta1 activity and stimulating VEGF expression

  4. MGP has a novel binding activity for vitronectin (show VTN Antibodies)

  5. Heat shock protein 70 (show HSP70 Antibodies) enhances vascular bone morphogenetic protein-4 (show BMP4 Antibodies) signaling by binding matrix Gla protein.

Matrix Gla Protein (MGP) Antigen Profile

Protein Summary

The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MGP

  • matrix Gla protein (mgp-A) antibody
  • matrix Gla protein (mgp) antibody
  • matrix Gla protein (MGP) antibody
  • matrix Gla protein (LOC100136171) antibody
  • matrix Gla protein (LOC100136434) antibody
  • Matrix Gla protein (mgp) antibody
  • matrix Gla protein (Mgp) antibody
  • matrix Gla protein-like (LOC100856382) antibody
  • LOC100136434 antibody
  • Mglap antibody
  • mgp antibody
  • mgp-A antibody
  • NTI antibody

Protein level used designations for MGP

matrix Gla protein , Matrix Gla protein , cell growth-inhibiting gene 36 protein , matrix gamma-carboxyglutamate (gla) protein

GENE ID SPECIES
373621 Xenopus laevis
402937 Danio rerio
465310 Pan troglodytes
574116 Macaca mulatta
611039 Canis lupus familiaris
100136171 Oncorhynchus mykiss
100136434 Salmo salar
100195997 Salmo salar
4256 Homo sapiens
17313 Mus musculus
25333 Rattus norvegicus
100008989 Oryctolagus cuniculus
100734539 Cavia porcellus
397206 Sus scrofa
282660 Bos taurus
395912 Gallus gallus
101106925 Ovis aries
100171893 Pongo abelii
102003225 Chinchilla lanigera
100856382 Canis lupus familiaris
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