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MGP Products

(Matrix Gla Protein (MGP))

Categories

The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Featured MGP Categories

MGP Antibodies

High quality antibodies with extensive validation data.

MGP ELISA Kits

Reliable ELISA kits for a wide range of species.

MGP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MGP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6143825
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7010638
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7159059
Quantity 100 μg
Datasheet Datasheet

Recommended MGP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN6957663
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957664
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6975472
Quantity 96 tests
Datasheet Datasheet

Recommended MGP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123851
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310886
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3133232
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MGP products

Wang, Lin, Hsu, Liu, Guo: "Altered Mineral Metabolism and Disequilibrium Between Calcification Promoters and Inhibitors in Chronic Hemodialysis Patients." in: Biological trace element research, Vol. 193, Issue 1, pp. 14-22, (2020) (PubMed).

Mizuiri, Nishizawa, Yamashita, Ono, Naito, Tanji, Usui, Doi, Masaki, Shigemoto: "Relationship of matrix Gla protein and vitamin K with vascular calcification in hemodialysis patients." in: Renal failure, Vol. 41, Issue 1, pp. 770-777, (2020) (PubMed).

Kuronuma, Yokoi, Fukuoka, Miyata, Maekawa, Tanaka, Matsubara, Goto, Matsuo, Han, Tsuruta, Murata, Okamoto, Hasegawa, Asano, Ito: "Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4." in: Heliyon, Vol. 6, Issue 4, pp. e03743, (2020) (PubMed).

Silaghi, Fodor, Gheorghe, Crăciun: "Serum total matrix Gla protein: Reference interval in healthy adults and variations in patients with vascular and osteoarticular diseases." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 490, pp. 128-134, (2019) (PubMed).

Feng, Liao, Huang, Lai, Luo, Du, Lin, Zhang, Qiu, Liu, Shen, Xiang, Zhang: "Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis." in: Cell death & disease, Vol. 9, Issue 6, pp. 691, (2018) (PubMed).

Kurnatowska, Grzelak, Masajtis-Zagajewska, Kaczmarska, Stefańczyk, Vermeer, Maresz, Nowicki: "Plasma Desphospho-Uncarboxylated Matrix Gla Protein as a Marker of Kidney Damage and Cardiovascular Risk in Advanced Stage of Chronic Kidney Disease." in: Kidney & blood pressure research, Vol. 41, Issue 3, pp. 231-9, (2016) (PubMed).

Doğan, Demir, Aksoy, Sağlam, Laloğlu, Yildirim: "Matrix-Gla Protein rs4236 [A/G] gene polymorphism and serum and GCF levels of MGP in patients with subgingival dental calculus." in: Archives of oral biology, Vol. 70, pp. 125-129, (2016) (PubMed).

Kurnatowska, Grzelak, Masajtis-Zagajewska, Kaczmarska, Stefa?czyk, Vermeer, Maresz, Nowicki: "Effect of vitamin K2 on progression of atherosclerosis and vascular calcification in nondialyzed patients with chronic kidney disease stages 3-5." in: Polskie Archiwum Medycyny Wewne?trznej, Vol. 125, Issue 9, pp. 631-40, (2015) (PubMed).

Najafi, Roustazadeh, Amirfarhangi, Kazemi: "Matrix Gla protein (MGP) promoter polymorphic variants and its serum level in stenosis of coronary artery." in: Molecular biology reports, Vol. 41, Issue 3, pp. 1779-86, (2014) (PubMed).

Lanham, Cagampang, Oreffo: "Maternal high-fat diet and offspring expression levels of vitamin k-dependent proteins." in: Endocrinology, Vol. 155, Issue 12, pp. 4749-61, (2014) (PubMed).

Synonyms and alternative names related to MGP

matrix Gla protein (MGP), matrix Gla protein (Mgp), matrix Gla protein L homeolog (mgp.L), matrix Gla protein (mgp), LOC100136434, MGLAP, Mglap, MGP, mgp, mgp-A, NTI

Protein level used designations for MGP

  • cell growth-inhibiting gene 36 protein
  • matrix gamma-carboxyglutamate (gla) protein
  • matrix Gla protein
  • Matrix Gla protein
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