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Matrix Metallopeptidase 24 (Membrane-inserted) Proteins (MMP24)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping Matrix Metallopeptidase 24 (Membrane-inserted) Antibodies (41) and Matrix Metallopeptidase 24 (Membrane-inserted) Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MMP24 17391 Q9R0S2
MMP24 83513 Q99PW6
MMP24 10893 Q9Y5R2
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Top Matrix Metallopeptidase 24 (Membrane-inserted) Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 5 to 6 Days
$440.82
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,523.67
Details
HOST_Escherichia coli (E. coli) Human His tag   200 μg Log in to see 5 to 6 Days
$6,446.82
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$999.22
Details

MMP24 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Rat (Rattus)

Human ,
, ,

More Proteins for Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) Interaction Partners

Xenopus laevis Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) interaction partners

  1. MT3-MMP expression is spatially and temporally restricted

  2. embryos injected with the soluble form of MT3-MMP exhibited decreased expression of these same marker genes

  3. metamorphic tail and intestine RNA levels of TIMP-2 (show TIMP2 Proteins), MT1-MMP (show MMP14 Proteins) and Gel-A, but not MT3-MMP or TIMP-3 (show TIMP3 Proteins), are elevated during periods of cell death and proliferation

Mouse (Murine) Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) interaction partners

  1. MT5-MMP emerges as a new pro-amyloidogenic regulator of APP (show APP Proteins) metabolism, whose deficiency alleviates amyloid pathology, neuroinflammation and cognitive decline.

  2. APP (show APP Proteins) carboxy-terminal fragment generation is mediated in part by membrane-bound matrix metalloproteinases such as MT5-MMP, referred to as eta-secretase activity

  3. identify MT5-MMP as a membrane-type metalloproteinase responsible for the shedding of the N-cadherin (show CDH2 Proteins) ectodomain in this niche

  4. MT5-MMP-deficient mice did not develop neuropathic pain with mechanical allodynia after sciatic nerve injury.

  5. MT5-MMP retrieval to the plasma membrane is regulated by Mint-3 (show APBA3 Proteins) by binding to its carboxyl end motif EWV

  6. These results suggest that ABP directs MT5-MMP proteolytic activity to growth cones and synaptic sites in neurons, where it may regulate axon pathfinding or synapse remodeling through proteolysis of cadherins or other ECM (show MMRN1 Proteins) or cell adhesion molecules.

  7. Findings demonstrate an essential role of MT5-MMP in the development of dermal neuro-immune synapses and suggest that this metalloproteinase may be a target for pain control.

Human Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) interaction partners

  1. Polymorphisms in MAP3K3 (show MAP3K3 Proteins), MMP24 and IGF1R (show IGF1R Proteins) are associated with greater height and act additively on height in children of an admixed population.

  2. In absolute mRNA levels, significant differences were found in expression of MMP2 (show MMP2 Proteins), MMP24, and MMP25 in gastric carcinoma compared with superficial gastritis.

  3. MMP-24 gene silencing by RNAi can suppress the invasiveness of ovarian cancer SKOV(3) cells in vitro.

  4. MT5-MMP retrieval to the plasma membrane is regulated by Mint-3 (show APBA3 Proteins) by binding to its carboxyl end motif EWV

  5. MT5-MMP is expressed in normal human endometrium and there is enhanced exprestion in endometrium from patients with entometriosis with strongest signal in epithelial cells.

  6. These results suggest more than one human MT5-MMP transcript may exist in the central nervous system.

Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24) Protein Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily\; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24.

Gene names and symbols associated with MMP24

  • matrix metallopeptidase 16 (membrane-inserted) (mmp16)
  • matrix metallopeptidase 24 (Mmp24)
  • matrix metallopeptidase 24 (mmp24)
  • matrix metallopeptidase 24 (membrane-inserted) (MMP24)
  • matrix metallopeptidase 24 (membrane-inserted) (Mmp24)
  • membrane-type 5 matrix metalloproteinase (LOC100101607)
  • AU040325 protein
  • MMP-24 protein
  • MMP24 protein
  • MMP25 protein
  • MT-MMP 5 protein
  • MT-MMP5 protein
  • mt3-mmp protein
  • Mt5-mmp protein
  • MT5MMP protein
  • MTMMP5 protein
  • si:ch211-239j9.5 protein

Protein level used designations for MMP24

Membrane-type 3 matrix metalloproteinase , MMP-21 , MMP-24 , MT-MMP 5 , matrix metalloproteinase 24 , matrix metalloproteinase-21 , matrix metalloproteinase-24 , membrane type 5-MMP , membrane-type matrix metalloproteinase 5 , membrane-type-5 matrix metalloproteinase , matrix metalloproteinase 24 (membrane-inserted) , membrane-type 5 matrix metalloproteinase , matrix metalloproteinase 24 preproprotein

GENE ID SPECIES
443562 Xenopus laevis
17391 Mus musculus
83513 Rattus norvegicus
571143 Danio rerio
10893 Homo sapiens
100328896 Oryctolagus cuniculus
100627204 Sus scrofa
100731826 Cavia porcellus
100101607 Oryctolagus cuniculus
419141 Gallus gallus
536622 Bos taurus
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