Matrix Metalloproteinase 20 Proteins (MMP20)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP20 Antibodies (74) and MMP20 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MMP20 9313 O60882
MMP20 240047 Q3U435
Rat MMP20 MMP20 300341  
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Top MMP20 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
Details
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days
$3,032.33
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,032.33
Details
HOST_Escherichia coli (E. coli) Mouse T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$736.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 7 to 9 Days
$791.18
Details

MMP20 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)
,

More Proteins for Matrix Metalloproteinase 20 (MMP20) Interaction Partners

Human Matrix Metalloproteinase 20 (MMP20) interaction partners

  1. DSPP (show DSPP Proteins)-MMP20 pair may play a role in the normal turnover of cell surface proteins and/or repair of pericellular matrix proteins of the basement membranes in the metabolically active duct epithelial system of the nephrons.

  2. Levels of matrix metalloproteinases MMP-19 (show MMP19 Proteins) and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC).

  3. The expression of MMP20 was lower in calcifying cystic odontogenic tumor when compared to all tumors and cysts.

  4. The growth of choroidal neovascularization in AMD (show AMD1 Proteins) would be affected by 2 genes: MMP20, a newly confirmed gene expressed in the retina, and ARMS2 (show ARMS2 Proteins)/HTRA1 (show HTRA1 Proteins), a well-known susceptibility gene for AMD (show AMD1 Proteins).

  5. Novel homozygous mutation MMP20 (c.1054G>A, p.Glu352Lys) genes were identified in amelogenesis imperfect consanguinity. Mutant MMP20 was expressed at a normal level but secreted only minimally with proteolytic function.

  6. expression of MMP-20 and co-expression and potential interaction with DSPP (show DSPP Proteins) in human major salivary gland tissues

  7. In absolute mRNA levels, significant differences were found in expression of MMP2 (show MMP2 Proteins), MMP24 (show MMP24 Proteins), and MMP25 (show MMP24 Proteins) in gastric carcinoma compared with superficial gastritis.

  8. The results identify MMP-20 as a broad activator of pro-KLKs, suggesting the potential for intersection of the KLK and MMP axes under pathological dysregulation of MMP-20 expression.

  9. Polymorphisms of MMP7 (show MMP7 Proteins) and MMP20 genes may be surrogate markers to predict long-term outcomes after kidney transplantation.

  10. IL-2 (show IL2 Proteins)-upregulated MT6 (show PRSS33 Proteins) cell-surface expression correlates with CD16 (show CD16 Proteins) downmodulation. MT6 (show PRSS33 Proteins), sequestered in intracellular compartments in unstimulated NK cells, translocates to the effector-target cell interface of CD16 (show CD16 Proteins)-mediated immunological synapses.

Xenopus laevis Matrix Metalloproteinase 20 (MMP20) interaction partners

  1. MMP20 in a common ancestor of tetrapods might have been recruited for the processing of AMEL (show AMELX Proteins) and conserved over 350 million years of evolution.

Mouse (Murine) Matrix Metalloproteinase 20 (MMP20) interaction partners

  1. MMP-20 action guides the growth morphology of the forming hydroxyapatite crystals and enhances their crystallinity.

  2. Matrix metalloproteinase-20 over-expression is detrimental to enamel development

  3. MMP20 cleaves extracellular domains of cadherin adherens junction proteins, both E- and N-cadherin (show CDH2 Proteins) transcripts are expressed at significantly higher levels in Mmp20 null mice; in Mmp20 ablated mice N-cadherin (show CDH2 Proteins) expression persists during maturation stage

  4. enamel of M180Tg/AmelxKO mice was thinner than WT, it had similar mechanical properties and decussating enamel prisms, which were abolished by the loss of MMP20 in the M180Tg/DKO mice.

  5. MMP20 may influence ameloblast developmental progression through hydrolysis of cadherin extracellular domains with associated release of transcription factor(s).

  6. Effect of kallikrein 4 (show KLK4 Proteins) loss on enamel mineralization: comparison with mice lacking matrix metalloproteinase 20.

  7. Runx2 (show RUNX2 Proteins) regulates the expression of ODAM (show ODAM Proteins) and nuclear ODAM (show ODAM Proteins) serves an important regulatory function in the mineralization of enamel through the regulation of MMP-20 apart from a different, currently unidentified, function of extracellular ODAM (show ODAM Proteins).

  8. expression of MMP-20 correlates with the stage-associated changes in the digestion of enamel proteins

  9. enamelysin activity is essential for proper enamel development in mice

  10. Enamelysin and collagen XVIII were co-localized in the developing enamel matrix and stratum intermedium and in the enamel-like tumor matrix of odontogenic tumors.

MMP20 Protein Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.

Gene names and symbols associated with MMP20

  • matrix metallopeptidase 20 (MMP20)
  • matrix metallopeptidase 25 (MMP25)
  • matrix metalloproteinase 20 (mmp20)
  • matrix metalloproteinase 20 (LOC100355428)
  • matrix metallopeptidase 25 (Mmp25)
  • matrix metallopeptidase 20 (enamelysin) (Mmp20)
  • matrix metallopeptidase 20 (Mmp20)
  • AI2A2 protein
  • F730048C11Rik protein
  • Leukolysin protein
  • MMP-20 protein
  • MMP-25 protein
  • mmp20 protein
  • MMP20A protein
  • MMP25 protein
  • MMPL1 protein
  • MT-MMP 6 protein
  • MT-MMP6 protein
  • MT6-MMP protein
  • MT6MMP protein
  • MTMMP6 protein

Protein level used designations for MMP20

enamel metalloproteinase , matrix metalloproteinase 20 (enamelysin) , matrix metalloproteinase-20 , leukolysin , matrix metallopeptidase-like 1 , matrix metalloproteinase 20 , matrix metalloproteinase 25 , matrix metalloproteinase-25 , matrix metalloproteinase-like 1 , membrane-type 6 matrix metalloproteinase , membrane-type matrix metalloproteinase 6 , membrane-type-6 matrix metalloproteinase , MMP-20 , enamelysin , matrix metallopeptidase 20 (enamelysin) , matrix metallopeptidase 25 , matrix metallopeptidase 20 , MMP-25 , matrix metalloproteinase

GENE ID SPECIES
9313 Homo sapiens
64386 Homo sapiens
281916 Bos taurus
740407 Pan troglodytes
100049153 Xenopus laevis
100355428 Oryctolagus cuniculus
240047 Mus musculus
396939 Sus scrofa
30800 Mus musculus
300341 Rattus norvegicus
611829 Canis lupus familiaris
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