anti-Meckel Syndrome, Type 1 (MKS1) Antibodies

The protein encoded by MKS1 localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Additionally we are shipping MKS1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MKS1 54903 Q9NXB0
MKS1 380718 Q5SW45
MKS1 287612 Q499Q5
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Top anti-MKS1 Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: MKS1 Antibody [NBP1-88691] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88691] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: MKS1 Antibody [NBP2-17303] - Sample (30 ug of whole cell lysate) A: JurKat 10% SDS PAGE gel, diluted at 1:2000. Immunohistochemistry-Paraffin: MKS1 Antibody [NBP2-17303] - Immunohistochemical analysis of paraffin-embedded A549 xenograft, using antibody at 1:100 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Cow Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: MKS1 Antibody [NLS6809] - Analysis of anti-DUSP22 antibody with human kidney. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: MKS1 Antibody [NBP1-88692] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of extract of various cells, using MKS1 antibody. 100 μL Log in to see 16 Days
$460.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IF, ELISA, WB   50 μL Log in to see 13 to 16 Days
$313.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 11 to 12 Days
$504.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 3 to 4 Days
$157.06
Details
Human Rabbit Un-conjugated IF, IP, ELISA, WB   200 μL Log in to see 12 to 14 Days
$588.50
Details

MKS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,


Mouse (Murine)


Rat (Rattus)


Top referenced anti-MKS1 Antibodies

  1. Human Polyclonal MKS1 Primary Antibody for IHC, IHC (p) - ABIN4334845 : Mahuzier, Gaudé, Grampa, Anselme, Silbermann, Leroux-Berger, Delacour, Ezan, Montcouquiol, Saunier, Schneider-Maunoury, Vesque: Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity. in The Journal of cell biology 2012 (PubMed)

More Antibodies against MKS1 Interaction Partners

Human Meckel Syndrome, Type 1 (MKS1) interaction partners

  1. Dnah11 (show DNAH11 Antibodies)(avc)(4) did not disrupt SHF (show SHF Antibodies) Hh signaling and caused Atrioventricular septal defects (AVSDs) only concurrently with heterotaxy, a left/right axis abnormality. In contrast, Mks1(avc)(6) disrupted SHF (show SHF Antibodies) Hh signaling and caused AVSDs without heterotaxy.We speculate that cilia gene mutations contribute to both syndromic and non-syndromic AVSDs in humans

  2. MKS1 functions in the transition zone at the base of the cilium to regulate ciliary INPP5E content.

  3. describe four patients with mild Joubert phenotypes who carry pathogenic mutations in either MKS1 or B9D1 (show B9D1 Antibodies), two genes previously implicated only in Meckel syndrome

  4. identification of a gene, MKS1,(Meckel syndrome) mutated in MKS families linked to 17q.

  5. The Meckel-Gruber Syndrome proteins MKS1 and meckelin (show TMEM67 Antibodies) interact and are required for primary cilium formation.

  6. Study concluded that MKS1 and MKS3 (show TMEM67 Antibodies) account for the majority of Meckel-Gruber syndrome; polydactyly is usually found in MKS1 but rare in MKS3 (show TMEM67 Antibodies); cases with no, or milder, CNS phenotypes were only found in MKS3 (show TMEM67 Antibodies).

  7. genotyping of MKS1 & MKS3 (show TMEM67 Antibodies) genes in a large, multiethnic cohort of 120 independent cases of Meckel syndrome; first results indicate that the MKS1 & MKS3 (show TMEM67 Antibodies) genes are each responsible for about 7% of MKS cases with various mutations in different populations

  8. Our results indicate that MKS1 mutations are not restricted to the Caucasian gene pool and suggest splicing defects are a crucial mutational mechanism in MKS1, and further genetic heterogeneity for MKS.

  9. Mutations in MKS1 is associated with Bardet-Biedl syndrome

  10. MKS-1 and MKS-1-related proteins 1 and 2 (MKSR-1 (show B9D1 Antibodies), MKSR-2 (show B9D2 Antibodies)), localize to transition zones/basal bodies of sensory cilia; subcellular localization is largely co-dependent, pointing to a functional relationship between the proteins

Mouse (Murine) Meckel Syndrome, Type 1 (MKS1) interaction partners

  1. demonstrated that the MKS (show MKKS Antibodies) transition zone complex cooperates with the BBSome to mediate trafficking of specific trans-membrane receptors to the cilium

  2. Dnah11 (show DNAH11 Antibodies)(avc)(4) did not disrupt SHF (show SHF Antibodies) Hh signaling and caused Atrioventricular septal defects (AVSDs) only concurrently with heterotaxy, a left/right axis abnormality. In contrast, Mks1(avc)(6) disrupted SHF (show SHF Antibodies) Hh signaling and caused AVSDs without heterotaxy.We speculate that cilia gene mutations contribute to both syndromic and non-syndromic AVSDs in humans

  3. Centriole localization of Mks1 is required for ciliogenesis of motile and non-motile cilia, but not for centriole assembly.

  4. Mks1 is required for ciliogenesis and shh (show SHH Antibodies) signaling in mouse model of human meckel syndrome.

  5. Mks1 expression in mouse embryos, as determined by in situ hybridization, agrees well with the tissue phenotype of MKS (show MKKS Antibodies).

MKS1 Antigen Profile

Protein Summary

The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MKS1

  • Meckel syndrome, type 1 (MKS1) antibody
  • Meckel syndrome, type 1 (Mks1) antibody
  • AK190930 antibody
  • B8d3 antibody
  • BBS13 antibody
  • MES antibody
  • MKS antibody
  • POC12 antibody

Protein level used designations for MKS1

FABB proteome-like protein , Meckel syndrome type 1 protein , POC12 centriolar protein homolog , Meckel syndrome type 1 protein homolog

GENE ID SPECIES
100056833 Equus caballus
54903 Homo sapiens
380718 Mus musculus
287612 Rattus norvegicus
491110 Canis lupus familiaris
100514538 Sus scrofa
530761 Bos taurus
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