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Mediator Complex Subunit 17 Proteins (MED17)

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. Additionally we are shipping MED17 Antibodies (71) and MED17 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MED17 9440 Q9NVC6
MED17 234959 Q8VCD5
Rat MED17 MED17 300367  
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Top MED17 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

MED17 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Mediator Complex Subunit 17 (MED17) Interaction Partners

Human Mediator Complex Subunit 17 (MED17) interaction partners

  1. TRAP80 is a selective regulator of hepatic lipogenesis and is required for LXR (show NR1H3 Proteins)-dependent SREBP-1c (show SREBF1 Proteins) activation.

  2. Studies indicate that the activation domain of p53 (show TP53 Proteins) (p53AD) binds directly to the MED17 subunit of Mediator, whereas the p53 (show TP53 Proteins) C-terminal domain (p53CTD) binds the MED1 (show MED1 Proteins) subunit.

  3. the p. L371P mutation in MED17 is a founder mutation in the Caucasus Jewish community and that homozygosity for this mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination.

MED17 Protein Profile

Protein Summary

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Gene names and symbols associated with MED17

  • mediator of RNA polymerase II transcription subunit 17 (AOR_1_2446154)
  • mediator of RNA polymerase II transcription subunit 17 (VDBG_01663)
  • Mediator of RNA polymerase II transcription subunit 17 (med17)
  • mediator complex subunit 17 (med17)
  • mediator complex subunit 17 (MED17)
  • mediator complex subunit 17 (Med17)
  • 77kDa protein
  • C330002H14Rik protein
  • Crsp6 protein
  • CRSP77 protein
  • DRIP80 protein
  • Trap80 protein

Protein level used designations for MED17

mediator of RNA polymerase II transcription subunit 17 , Mediator of RNA polymerase II transcription subunit 17 , CRSP complex subunit 6 , cofactor required for Sp1 transcriptional activation subunit 6 , cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa , ARC77 , activator-recruited cofactor 77 kDa component , thyroid hormone receptor-associated protein complex 80 kDa component , transcriptional coactivator CRSP77 , vitamin D3 receptor-interacting protein complex 80 kDa component , cofactor required for Sp1 transcriptional activation, subunit 6 (77kD) , cofactor required for Sp1 transcriptional activation, subunit 6

GENE ID SPECIES
5992434 Aspergillus oryzae RIB40
9533803 Verticillium alfalfae VaMs.102
100380574 Salmo salar
100101325 Xenopus laevis
419000 Gallus gallus
9440 Homo sapiens
476769 Canis lupus familiaris
541303 Bos taurus
234959 Mus musculus
300367 Rattus norvegicus
101106726 Ovis aries
Selected quality suppliers for MED17 Proteins (MED17)
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