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anti-Melanocortin 3 Receptor (MC3R) Antibodies

MC3R encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. Additionally we are shipping MC3R Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MC3R 17201 P33033
MC3R 4159 P41968
MC3R 29310 P32244
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Top anti-MC3R Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MC3R Antibody (Center) in K562 cell line lysa... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (fro), IP, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185386 (1µg/ml) staining of Human Brain lysate (35µg protein in RI... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Chimpanzee Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (fro), IP, WB   0.25 mg Log in to see 10 to 12 Days
$485.10
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of MC3R Antibody (Center) (ABIN652665) in K562 c... MC3R Antibody (Center) (ABIN652665) flow cytometric analysis of K562 c... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (fro), IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-MC3 Receptor antibody  ABIN1049045 IHC staining of human brain, c... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$369.79
Details

MC3R Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , ,

Human , , ,
, ,
Rat (Rattus) ,

Top referenced anti-MC3R Antibodies

  1. Human Polyclonal MC3R Primary Antibody for IHC (fro), IP - ABIN493099 : Wikberg, Muceniece, Mandrika, Prusis, Lindblom, Post, Skottner: New aspects on the melanocortins and their receptors. in Pharmacological research : the official journal of the Italian Pharmacological Society 2000 (PubMed)
    Show all 4 references for ABIN493099

  2. Human Polyclonal MC3R Primary Antibody for IHC (fro), IP - ABIN2712096 : Butler, Cone: Knockout studies defining different roles for melanocortin receptors in energy homeostasis. in Annals of the New York Academy of Sciences 2003 (PubMed)
    Show all 4 references for ABIN2712096

  3. Human Polyclonal MC3R Primary Antibody for IHC (fro), IP - ABIN493097 : Getting, Christian, Lam, Gavins, Flower, Schiöth, Perretti: Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 4 references for ABIN493097

  4. Human Polyclonal MC3R Primary Antibody for EIA, WB - ABIN453742 : Magenis, Smith, Nadeau, Johnson, Mountjoy, Cone: Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human. in Mammalian genome : official journal of the International Mammalian Genome Society 1994 (PubMed)
    Show all 2 references for ABIN453742

  5. Chimpanzee Polyclonal MC3R Primary Antibody for WB - ABIN374548 : Mühlhäusler, Adam, Marrocco, Findlay, Roberts, McFarlane, Kauter, McMillen et al.: Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late ... in The Journal of physiology 2005 (PubMed)

More Antibodies against MC3R Interaction Partners

Mouse (Murine) Melanocortin 3 Receptor (MC3R) interaction partners

  1. Replacing murine Mc3r with and double-mutant (C17A+G241A) human MC3R showed greater weight and fat mass, increased energy intake and feeding efficiency.

  2. MC1-mediated effects were reduced, and MC3 anti-inflammatory circuits predominated. Mice bearing a nonfunctional MC1 displayed a transient exacerbation of neutrophil recruitment after global I/R, which diminished by 2 hours.

  3. The minimum promoter region required for Mc3r expression has been identified, along with two binding sites for AP-1 (show JUN Antibodies) and ATF4 (show ATF4 Antibodies) and in the 5' upstream-flanking region of Mc3r that are essential for Mc3r expression.

  4. 3' RACE experiments using hypothalamic RNA indicated the 3' UT (show UTS2R Antibodies)R terminates approximately 1286 bases after the translational stop codon, with a previously unknown 787 base splice between consensus splice donor and acceptor sites.

  5. These data reveal novel protective properties of endogenous MC3 on periodontal status in health and disease

  6. Data suggest that Mc3r (not Mc4r (show MC4R Antibodies)) is expressed in 1/3 of dopaminergic neurons in ventral tegmental area (VTA); global deletion of Mc3r in knockout mice increases VTA dopamine by 42% and decreases sucrose intake/preference in female (not male) mice.

  7. Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin (show GHRL Antibodies) and melanocortin-3 receptors.

  8. data suggest that the melanocortin-3 receptor is involved in the control of energy balance and the expression of rhythms anticipating nutrient intake.

  9. MC(3) plays a subtle role in the regulation of food intake

  10. Compared with WT, MC4R (show MC4R Antibodies)-/- showed no activation in area postrema but showed normal activation in paraventricular hypothalamus, whereas MC3R-/- showed reduced activation in PVN but not in AP.

Human Melanocortin 3 Receptor (MC3R) interaction partners

  1. melanocortin receptors MC2R (show MC2R Antibodies), MC3R and MC5R (show MC5R Antibodies) are most abundantly expressed in glandular epithelium of the endometrium

  2. Replacing murine Mc3r with and double-mutant (C17A+G241A) human MC3R showed greater weight and fat mass, increased energy intake and feeding efficiency.

  3. the DPLIY motif and helix 8 was important for MC3R activation and signal transduction. The data led to a better understanding of the structure-function relationship of MC3R.

  4. novel data about the structure-function relationship of MC3R, identifying residues important for receptor function; some studied mutations exhibited biased signaling, preferentially activating one intracellular signaling pathway.

  5. propose three potential human candidate genes for voluntary physical exercise levels (MC3R, CYP24A1 (show CYP24A1 Antibodies), and GRM8 (show GRM8 Antibodies)).

  6. The cytoplasmic end of transmembrane domain 3 and the intracellular loop 2 were critical for MC3R function.

  7. MC3R polymorphism is marginally associated in the development of pulmonary tuberculosis in Korean population.

  8. MC3R is a 2-exon gene that requires a 5' UTR for translation, localization, and potential interaction with MRAP2

  9. 3' RACE experiments using MC3R transcript indicated the 3' UTR (show UTS2R Antibodies) terminates approximately 115-160 bases after the translational stop codon.

  10. observed that a missense variant (rs3827103)in MC3R and the haplotype that it forms with an upstream (rs3746619) variant are associated with systolic blood pressure (SBP (show SHBG Antibodies)); individuals who with these variants exhibit downregulation of MC3R expression and a positive correlation between leptin (show LEP Antibodies) levels and SBP (show SHBG Antibodies)

MC3R Antigen Profile

Protein Summary

This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.

Gene names and symbols associated with MC3R

  • melanocortin 3 receptor (mc3r) antibody
  • melanocortin 3 receptor (MC3R) antibody
  • melanocortin 3 receptor (Mc3r) antibody
  • BMIQ9 antibody
  • MC3 antibody
  • MC3-R antibody
  • OB20 antibody
  • OQTL antibody
  • zgc:194235 antibody

Protein level used designations for MC3R

melanocortin receptor 3 , melanocortin-3 receptor , obesity quantitative trait locus , MC3-R

GENE ID SPECIES
353153 Danio rerio
485938 Canis lupus familiaris
100054477 Equus caballus
100141404 Sus scrofa
17201 Mus musculus
4159 Homo sapiens
469978 Pan troglodytes
29310 Rattus norvegicus
Selected quality suppliers for anti-MC3R (MC3R) Antibodies
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